Journal of Biological Chemistry, 2012 Background: HS has been implicated in regulating ESC differentiation. Results: Mouse ESCs lacking EXT1 fail to differentiate into mesoderm. Restoration of the FGF and BMP signaling each partially rescued the mesoderm differentiation defect.
D. Kraushaar +8 more
semanticscholar +1 more source
Journal of Developmental Biology, 2016 In gnathostomes, limb buds arise from the lateral plate mesoderm at discrete positions along the body axis. Specification of these limb-forming fields can be subdivided into several steps.
Mikiko Tanaka
doaj +1 more source
Xwnt-5A: a maternal Wnt that affects morphogenetic movements after overexpression in embryos of Xenopus laevis [PDF]
, 1993 To contribute to an understanding of the roles and mechanisms of action of Wnts in early vertebrate development, we have characterized the normal expression of Xenopus laevis Wnt-5A, and investigated the consequences of misexpression of this putative ...
Campbell, Robert M. +5 more
core
T (Brachyury) is a direct target of Wnt3a during paraxial mesoderm specification.
Genes & Development, 1999 Wnt3a encodes a signal that is expressed in the primitive streak of the gastrulating mouse embryo and is required for paraxial mesoderm development. In its absence cells adopt ectopic neural fates.
T. Yamaguchi +4 more
semanticscholar +1 more source
A comparative molecular approach to mesodermal patterning in basal deuterostomes: the expression pattern of Brachyury in the enteropneust hemichordate Ptychodera flava [PDF]
, 1999 This work concerns the formation of mesoderm in the development of an enteropneust hemichordate, Ptychodera flava, and the expression of the Brachyury gene during this process. Brachyury expression occurs in two distinct phases.
Cameron, R. Andrew +4 more
core
In vitro Characteristics of Heterogeneous Equine Hoof Progenitor Cell Isolates
Frontiers in Bioengineering and Biotechnology, 2019 Damage to an ectodermal-mesodermal interface like that in the equine hoof and human finger nail bed can permanently alter tissue structure and associated function.
Qingqiu Yang +6 more
doaj +1 more source
On the development of the mesoderm of Crustacea, and on that of the organs derived from it [PDF]
, 1891 M. Louis Roule
openalex +1 more source
Inductive Capacities for the Dorsal Mesoderm of the Dorsal Marginal Zone and Pharyngeal Endoderm in the Very Early Gastrula of the Newt, and Presumptive Pharyngeal Endoderm as an Initiator of the Organization Center* [PDF]
, 1985 Tadao Hama +4 more
openalex +1 more source
Inverse agonism of retinoic acid receptors directs epiblast cells into the paraxial mesoderm lineage
Stem Cell Research, 2018 We have investigated the differentiation of paraxial mesoderm from mouse embryonic stem cells utilizing a Tbx6-EYFP/Brachyury (T)-Cherry dual reporter system.
Ryan P. Russell +3 more
doaj