Results 101 to 110 of about 94,714 (283)

Are physiological oscillations physiological?

open access: yesThe Journal of Physiology, EarlyView., 2023
Abstract figure legend Mechanisms and functions of physiological oscillations. Abstract Despite widespread and striking examples of physiological oscillations, their functional role is often unclear. Even glycolysis, the paradigm example of oscillatory biochemistry, has seen questions about its oscillatory function.
Lingyun (Ivy) Xiong, Alan Garfinkel
wiley   +1 more source

A comprehensive embryonic staging series of the turtle Trachemys scripta

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Turtles hold a unique place in vertebrate evolutionary history, making them critical assets in embryology research. Yet, they remain understudied as potential model organisms in the field. Here, to support experimental manipulations with turtle embryos, we have created a complete normal table of development for comprehensive ...
Christina M. Noravian   +6 more
wiley   +1 more source

An unexpected role of IL10 in mesoderm induction and differentiation from pluripotent stem cells: Implications in zebrafish angiogenic sprouting, vascular organoid development, and therapeutic angiogenesis

open access: yesEuropean Journal of Cell Biology
Mesoderm induction is a crucial step for vascular cell specification, vascular development and vasculogenesis. However, the cellular and molecular mechanisms underlying mesoderm induction remain elusive.
Kaiyuan Niu   +10 more
doaj   +1 more source

Evaluation of commonly used ectoderm markers in iPSC trilineage differentiation. [PDF]

open access: yes, 2019
Patient-derived induced pluripotent stem cells (iPSCs) have become a promising resource for exploring genetics of complex diseases, discovering new drugs, and advancing regenerative medicine.
Iacovino, Michelina   +11 more
core  

Rodent monocyte‐derived macrophages do not express CD163: Comparative analysis using macrophages from living boreoeutherians

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background CD163 is a scavenger receptor predominantly expressed on the surfaces of macrophages in various mammalian species and is a marker of anti‐inflammatory (M2‐like) macrophages. High density of CD163‐positive tumor‐associated macrophages (TAMs) is associated with worse prognosis in various patient tumors.
Yoichi Saito   +9 more
wiley   +1 more source

Crumbs2 gets mesoderm moving [PDF]

open access: yesScience, 2017
Development![Figure][1] The protein Crumbs2 is essential for gastrulation. PHOTO: RAMKUMAR ET AL., NATURE CELL BIOLOGY 18 (21 NOVEMBER 2016) © NATURE The epithelial-to-mesenchymal transition (EMT) is the process by which cells move out of a structured, epithelial tissue and become motile.
openaire   +2 more sources

Differential sensitivity of midline development to mitosis during and after primitive streak extension

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Midline establishment is a fundamental process during early embryogenesis for Bilaterians. Midline morphogenesis in non‐amniotes can occur without mitosis, through Planar Cell Polarity (PCP) signaling. By contrast, amniotes utilize both cellular processes for developing the early midline landmark, the primitive streak (PS).
Zhiling Zhao, Rieko Asai, Takashi Mikawa
wiley   +1 more source

Developmental Mechanism of Limb Field Specification along the Anterior–Posterior Axis during Vertebrate Evolution

open access: yesJournal of Developmental Biology, 2016
In gnathostomes, limb buds arise from the lateral plate mesoderm at discrete positions along the body axis. Specification of these limb-forming fields can be subdivided into several steps.
Mikiko Tanaka
doaj   +1 more source

Expression of mutant TIE2 p.L914F during mouse development causes embryonic lethality and defects in vascular remodeling

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Sporadic venous malformation (VM) is associated with the hyperactivating p.L914F mutation in TIE2, a receptor tyrosine kinase essential for vascular development. This mutation is not found in hereditary VM, suggesting incompatibility with life when expressed during early vascular development.
Lindsay J. Bischoff   +6 more
wiley   +1 more source

Loss of Atoh8 Affects Neurocranial and Axial Skeleton Development in Zebrafish

open access: yesFrontiers in Bioscience-Landmark
Background: The basic helix-loop-helix (bHLH) transcription factor atonal homologue 8 (Atoh8) has been implicated in various developmental and physiological processes by means of transient knockdown and conditional knockout approaches ...
Ninfa Fragale   +3 more
doaj   +1 more source

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