Results 61 to 70 of about 113,853 (284)
Summary: Liver sinusoidal endothelial cells (LSECs) form the predominant microvasculature in the liver where they carry out many functions including the secretion of coagulation factor VIII (FVIII).
Blair K. Gage+4 more
doaj
Evolutionary conservation of early mesoderm specification by mechanotransduction in Bilateria
The modulation of developmental biochemical pathways by mechanical cues is an emerging feature of animal development, but its evolutionary origins have not been explored.
T. Brunet+16 more
semanticscholar +1 more source
The bone morphogenetic protein (BMP) signaling pathway is highly conserved across many species, and its importance for the patterning of the skeletal system has been demonstrated.
Guiqian Chen+7 more
doaj +1 more source
Tukushi modulates Xnr2, FGF, and and BMP signalling: Regulation of Xenopus Germ Layer Formation [PDF]
BACKGROUND: Cell-cell communication is essential in tissue patterning. In early amphibian development, mesoderm is formed in the blastula-stage embryo through inductive interactions in which vegetal cells act on overlying equatorial cells. Members of the
Almeida, AD+4 more
core
Paradigm Shifts In Neural Induction [PDF]
The molecularization of developmental biology was originally seen as a challenge to the integrity of that discipline. However, important new insights from the analysis of gene expression soon transformed the field from one of experimental anatomy to one ...
Gilbert, Scott F.
core +2 more sources
Embryological Consideration of Dural AVFs in Relation to the Neural Crest and the Mesoderm [PDF]
Intracranial and spinal dural arteriovenous fistulas (DAVFs) are vascular pathologies of the dural membrane with arteriovenous shunts. They are abnormal communications between arteries and veins or dural venous sinuses that sit between the two sheets of ...
Michihiro Tanaka
doaj +1 more source
Characterizing the zebrafish organizer: microsurgical analysis at the early-shield stage [PDF]
The appearance of the embryonic shield, a slight thickening at the leading edge of the blastoderm during the formation of the germ ring, is one of the first signs of dorsoventral polarity in the zebrafish embryo.
Fraser, Scott E., Shih, John
core
The early stages of heart development: insights from chicken embryos [PDF]
The heart is the first functioning organ in the developing embryo and the detailed understanding of the molecular and cellular mechanisms involved in its formation provides insights into congenital malformations affecting its function and therefore the ...
Alsan+19 more
core +2 more sources
Directed transdifferentiation of mouse mesoderm to heart tissue by defined factors
Heart disease is the leading cause of mortality and morbidity in the western world. The heart has little regenerative capacity after damage, leading to much interest in understanding the factors required to produce new cardiac myocytes.
J. Takeuchi, B. Bruneau
semanticscholar +1 more source
Inhibition of mesoderm formation by follistatin [PDF]
Mesoderm induction requires interaction between cells of the animal and vegetal hemispheres of the embryo. Several molecules have been proposed as candidates for mesoderm-inducing signals, with activin a particularly strong candidate. However, it has not been possible to inhibit mesoderm formation in vivo by specifically blocking activin action ...
Marchant, Lorena+2 more
openaire +3 more sources