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Mesolimbic novelty processing in older adults. [PDF]
Normal aging is associated with neuronal loss in the dopaminergic midbrain (substantia nigra/ventral tegmental area, SN/VTA), a region that has recently been implicated in processing novel stimuli as part of a mesolimbic network including the hippocampus.
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Insulin and endocannabinoids in the mesolimbic system
Journal of Neuroendocrinology, 2021Abstract Easy access to palatable food and an abundance of food‐related cues exacerbate non‐homeostatic feeding. The metabolic and economical sequelae of non‐homeostatic feeding outweigh those of homeostatic feeding and contribute significantly to the global obesity pandemic.
Nada A. Sallam, Stephanie L. Borgland
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The aim of the present study was to determine whether a dopaminergic mesolimbic pathway, as found in the brain of amniotes, also exists in anuran amphibians.
Oscar Marin +2 more
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Mesolimbic dopaminergic pathways in fear conditioning
Progress in Neurobiology, 2004One of the most common paradigms used to study the biological basis of emotion, as well as of learning and memory, is Pavlovian fear conditioning. In the acquisition phase of a fear conditioning experiment, an emotionally neutral conditioned stimulus (CS)--which can either be a discrete stimulus, such as a tone, or a contextual stimulus, such as a ...
Pezze MA, Feldon J
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LSD as an agonist at mesolimbic dopamine receptors
Psychopharmacologia, 1975The dopamine agonist apomorphine (1.0 mg/kg i.p.) produced an enhanced stimulation of locomotor activity compared to control animals in rats injected bilaterally 14 days previously with 6-hydroxydopamine (6OHDA) into the nucleus accumbens. (+)-Lysergic acid diethylamide (LSD) also produced a marked stimulation of locomotor activity in the 6OHDA treated
P H, Kelly, L L, Iversen
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