Results 31 to 40 of about 27,540 (239)
The mesolimbic dopamine activity signatures of relapse to alcohol-seeking [PDF]
, 2020 The mesolimbic dopamine system comprises distinct compartments supporting different functions in learning and motivation. Less well understood is how complex addiction-related behaviours emerge from activity patterns across these compartments.
Liu, Yu
core +1 more source
NeuroImage, 2020 Chronic low back pain (cLBP) is a prevalent disorder. A growing body of evidence linking the pathology of the reward network to chronic pain suggests that pain sensitization may contribute to cLBP chronification via disruptions of mesocortical and ...
Siyi Yu +17 more
doaj +1 more source
Modulation of the mesolimbic dopamine system by leptin [PDF]
Brain Research, 2010 Nutritional status modulates many forms of reward-seeking behavior, with caloric restriction increasing the drive for drugs of abuse as well as for food. Understanding the interactions between the mesolimbic dopamine (DA) system (which mediates the incentive salience of natural and artificial rewards) and the neural and hormonal systems that sense and ...
Darren M, Opland +2 more
openaire +2 more sources
Cocaine Inhibition of Nicotinic Acetylcholine ReceptorsInfluences Dopamine Release
Frontiers in Synaptic Neuroscience, 2014 Nicotinic acetylcholine receptors (nAChRs) potently regulate dopamine (DA) release in the striatum and alter cocaine’s ability to reinforce behaviors.
Alexandra eAcevedo-Rodriguez +7 more
doaj +1 more source
Continuous Subcutaneous Apomorphine as a Temporary Bridging Therapy for Dopamine Dysregulation Syndrome in Patients with Deep Brain Stimulation [PDF]
Mov Disord Clin PractAbstract Background Dopamine dysregulation syndrome (DDS) is a challenging complication of dopaminergic therapy in Parkinson's disease and can persist despite subthalamic deep brain stimulation (STN‐DBS). We evaluated a temporary bridging concept in which oral dopaminergic medication was replaced by continuous subcutaneous apomorphine infusion while ...
Binder T +8 more
europepmc +2 more sources
Frontiers in Behavioral Neuroscience, 2023 Alcohol use remains a major public health concern and is especially prevalent during adolescence. Adolescent alcohol use has been linked to several behavioral abnormalities in later life, including increased risk taking and impulsivity. Accordingly, when
Ari M. Asarch +15 more
doaj +1 more source
Humor Modulates the Mesolimbic Reward Centers [PDF]
Neuron, 2003 Humor plays an essential role in many facets of human life including psychological, social, and somatic functioning. Recently, neuroimaging has been applied to this critical human attribute, shedding light on the affective, cognitive, and motor networks involved in humor processing.
Mobbs, Dean +4 more
openaire +3 more sources
Acute high fat diet consumption activates the mesolimbic circuit and requires orexin signaling in a mouse model. [PDF]
PLoS ONE, 2014 Overconsumption of palatable energy-dense foods has negative health implications and it is associated with obesity and several eating disorders. Currently, little is known about the neuronal circuitries activated by the acute ingestion of a rewarding ...
Spring Valdivia +3 more
doaj +1 more source
, 1980 Previous work has shown that 6–12 months continuous trifluoperazine (TFP) administration to rats causes striatal dopamine receptor supersensitivity. We have now replicated our original findings in the striatum and report concurrent changes in mesolimbic ...
Marsden, C.D. +3 more
core +1 more source
The central GLP-1: implications for food and drug reward
Frontiers in Neuroscience, 2013 Glucagon-like-peptide-1 (GLP-1) and its long acting analogues comprise a novel class of type 2 diabetes (T2D) treatment. What makes them unique among other T2D drugs is their concurrent ability to reduce food intake, a great benefit considering the ...
Karolina Patrycja Skibicka
doaj +1 more source