Results 31 to 40 of about 382,700 (243)
The expression of renin-angiotensin system components in human carotid plaque [PDF]
Vojnosanitetski PregledBackground/Aim. The renin-angiotensin system (RAS) is linked to the development of atherosclerosis (As), including its initiation and progression. Besides the well-known angio-tensin-converting enzyme (ACE), two newer RAS family members are related to ...
Kolaković Ana +5 more
doaj +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Skills for business and management
Journal of Learning Development in Higher Education, 2021 A book review of Sedgley, M. (2020) Skills for business and management.
Hazel Messenger
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Metabolic Messengers: glucagon
Nature Metabolism, 2023 Plasma glucose is tightly regulated via the secretion of the two glucose-regulating hormones insulin and glucagon. Situated next to the insulin-secreting β-cells, the α-cells produce and secrete glucagon-one of the body's few blood glucose-increasing hormones.
Patrick E. MacDonald, Patrik Rorsman
openaire +2 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Innovation and SustainabilityThe article analyzes social networks and their role in the modern world as a key tool for uniting social groups of builders of various specialties. It has been found that social networks provide convenient and fast communication between specialists ...
S. Murha
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Metabolic Messengers: endocannabinoids
Nature Metabolism, 2022 We also thank all the members of A.B.-G.’s, J.P.B.’s and G.M.’s labs for useful discussions and for their invaluable support. The work of A.B.-G. is supported by: Agencia Estatal de Investigación-FEDER (RTI2018-093667-A-100); the ERC starting Grant (HighMemory, #948217); the IBRO Return Home Fellowships 2019 and the Ramon y Cajal programme (RYC-2017 ...
Arnau Busquets-García +2 more
openaire +4 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Индустрии впечатлений: Технологии социокультурных исследованийThe object of the study is an electronic nomad who creates and posts elements of their own existential spectacle on messenger channels and social media pages.
Elena Iakovleva / Елена Людвиговна Яковлева
doaj +1 more source