Quercetin alleviates inflammation induced by porcine reproductive and respiratory syndrome virus in MARC-145 cells through the regulation of arachidonic acid and glutamine metabolism. [PDF]
Vet Med SciPRRSV stimulation resulted in hydrolysis of glycerophospholipids to release linoleic acid and arachidonic acid, activating the NF‐κB pathway and inducing inflammation. After intervention with quercetin, it reduced the production of linoleic acid and arachidonic acid, increased glutamine content, blocked NF‐κB pathway activation, and reduced the levels ...
Guang Q +6 more
europepmc +2 more sources
Molecules, 2019 Microwave-assisted syntheses of novel ring d-condensed 2-pyrazolines in the estrone series were efficiently carried out from steroidal α,β-enones and hydrazine derivatives. The ring-closure reaction of 16-benzylidene estrone 3-methyl ether with
Gergő Mótyán +3 more
doaj +1 more source
Rational drug repurposing for alzheimer’s treatment using in-silico ligand and structure-based approaches [PDF]
Brazilian Journal of Pharmaceutical SciencesAlzheimer’s disease is a devastating neurodegenerative disorder characterized by memory loss and cognitive decline. New AD treatments are essential, and drug repositioning is a promising approach.
Karishma Rathi +4 more
doaj +1 more source
The influence of norethindrone and mestranol on pituitary–adrenal function
, 1968 Female Wistar rats were force-fed either Ortho-Novum (66 μg norethindrone and 1 μg mestranol), norethindrone (66 μg), mestranol (1 μg), or water daily for 1 month.
David R. Usher
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EFICIÊNCIA DO TRATAMENTO ANAERÓBIO NA REMOÇÃO DE HORMÔNIOS VETERINÁRIOS DO DEJETO LÍQUIDO SUÍNO
Evidência, 2016 A contribuição de hormônios ao meio ambiente está ligada diretamente à eficiência da remoção de tais moléculas nas plantas de tratamento de águas residuárias. A remoção depende das características do efluente e dos processos adotados.
Rafael Gotardo +2 more
doaj +1 more source
Body fluid volumes in rats with mestranol-induced hypertension
, 1986 Because estrogens have been reported to produce sodium retention, this study investigated the possibility that hypertension in rats resulting from the ingestion of an estrogen used as an oral contraceptive could be due to increases in body fluid volumes.
D. W. Zeigler +5 more
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Contraceptive steroids increase hepatic uptake of chylomicron remnants in healthy young women.
Journal of Lipid Research, 1988 In an investigation of alterations in cholesterol metabolism during contraceptive steroid use, we studied plasma clearance of chylomicron remnants. Six healthy women were studied on and off contraceptive steroid therapy.
F Berr, R H Eckel, F Kern, Jr
doaj +1 more source
Influence of natural and synthetic estrogens on the course of autoimmune disease in the nzb/nzw mouse [PDF]
, 1973 Antinuclear antibodies were found in 64% of serum samples obtained from male NZB/NZW mice after 6 weeks of treatment with mestranol. Both female and male mice responded to this synthetic female hormone with marked elevations of serum Α 2 - and Β ...
Bole, Giles G., Walker, Sara Ellen
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Alzheimer's &Dementia, Volume 21, Issue 11, November 2025.Abstract Female sex is associated with higher incidence and risk of dementia. Estrogen may represent one important mechanism contributing to the increase in incidence rates. In this review, we synthesize narratively the evidence for associations between estrogen—across the life course from menarche to menopause, estrogen‐containing hormonal ...
Sarah Gregory +19 more
wiley +1 more source
Effect of Tetracycline on Norethynodrel- and Mestranol-Induced Dental Caries in Rats
, 1974 Weanling female rats were given subcutaneous injections of contraceptive steroids (norethynodrel and mestranol), tetracycline supplements in drinking water, or both, for seven weeks.
F.T.Y. Liu, T.H. Alms, H.S. Lin
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