Results 161 to 170 of about 14,708 (190)

Met-enkephalin induced alterations of macrophage functions

Molecular Immunology, 1984
Met-enkephalin /Met-enk/ was found to stimulate IgG2a-mediated antibody dependent cytotoxicity /ADCC/ of thioglycollate elicited rat peritoneal macrophages /PM/ through naloxone-sensitive opiate receptors in concentrations ranging from 10(-9) - 14(-7) M.
G, Fóris, G A, Medgyesi, E, Gyimesi, M, Hauck   +3 more
openaire   +2 more sources

Met-enkephalin induced escape from dexamethasone immunosuppression

Neuropeptides, 1993
The present study was undertaken to examine whether and what type of interaction occurs between a synthetic glucocorticoid, dexamethasone (DEX) and an opioid peptide, met-enkephalin (MENK) upon superoxide anion (O2-) release from human polymorphonuclear cells (PMN).
Haberstock-Debić, Helena, Marotti, Tatjana   +1 more
openaire   +4 more sources

Intracerebroventricular met-enkephalin administration modulates adjuvant arthritis

Brain Research, 2000
The purpose of this study was to investigate the anti-inflammatory properties of intracerebroventricular met-enkephalin (met-enk) administration in an animal model of arthritis. Adjuvant arthritis was induced in rats by intradermal inoculation of mycobacterium butyricum and the effects of intraventricular met-enk+thiorphan (enkephalinase inhibitor ...
A M, Elhassan, N, Papadogiannakis, A, Adem, I, Suliman, A, Gad, J U, Lindgren   +5 more
openaire   +2 more sources

Interaction of Met‐Enkephalin with Human Granulocytes

Annals of the New York Academy of Sciences, 1987
Met-enkephalin has been found to have an effect on cell shape and motility of human polymorphonuclear leukocytes (PMNs). Specific binding of tritium-labeled Met-enkephalin to the cells could not be demonstrated. There was a rapid proteolytic degradation of the peptide in the medium, followed by uptake of the labeled tyrosine.
E G, Fischer, N E, Falke
openaire   +2 more sources

Met-enkephalin-like immunoreactivity in Merkel cells

Cell and Tissue Research, 1979
The Merkel cells from sinus hair follicles of rats were investigated by immunohistochemistry using different antisera against neuropeptides and gastroenteropancreatic (GEP)-hormones. For the first time it has been demonstrated that Merkel cells exhibit an immunoreactivity towards metenkephalin (methionine-enkephalin).
W, Hartschuh, E, Weihe, M, Büchler, V, Helmstaedter, G E, Feurle, W G, Forssmann   +5 more
openaire   +2 more sources

Interaction of met-enkephalin and corticosteroids in immunomodulation

International Journal of Immunopharmacology, 1992
The effect of Met-enkephalin (MENK) on several immune functions, corticosterone (CS) and adrenocorticotropin (ACTH) levels in the plasma was studied in adrenalectomized (ADX) and sham-adrenalectomized (SADX) mice. Multiple Met-enkephalin injections (10 mg/kg per day in two injections 12 h apart, for 4 days) increased the plaque-forming cell response to
Gabrilovac, Jelka, Ročić, Boris, Marotti, Tatjana, Haberstock-Debić, Helena   +3 more
openaire   +3 more sources

Existence of Met-enkephalin-Arg6-Gly7-Leu8 with Met-enkephalin, Leu-enkephalin and Met-enkephalin-Arg6-Phe7 in the brain of guinea pig, rat and golden hamster

Biochemical and Biophysical Research Communications, 1982
Abstract High performance liquid chromatography (HPLC) coupled with specific radioimmunoassays for methionine-enkephalin-Arg6-Gly7-Leu8 (Met-E-Arg6-Gly7-Leu8), methionine-enkephalin (Met-E), leucine-enkephalin (Leu-E) and methionine-enkephalin-Arg6-Phe7 (Met-E-Arg6-Phe7) has demonstrated that Met-E-Arg6-Gly7-Leu8 exists together with Met-E, Leu-E and
Y, Ikeda, K, Nakao, T, Yoshimasa, N, Yanaihara, S, Numa, H, Imura   +5 more
openaire   +2 more sources

Enzymatic synthesis of Leu- and Met-enkephalin

Biochemical and Biophysical Research Communications, 1979
Abstract The protease-catalyzed synthesis of Leu- and Met-enkephalin is reported. Each peptide bond of the endogeneous opiate-pentapeptides was formed either by papain or α-chymotrypsin catalysis. N-acyl amino acids and peptides or their ester derivatives served as substrates whereas amino acid and peptide phenylhydrazides were used as nucleophiles ...
openaire   +2 more sources

Immunomodulation by two potent analogs of met-enkephalin

Immunopharmacology, 1997
Met-enkephalin (Tyr-Gly-Gly-Phe-Met) and its more stable analogs, Tyr-D-Ala-Gly-MePhe-Met-NHC3H gamma-iso (1) and Tyr-D-Ala-Gly-MePhe-Gly-NHC3H gamma-iso (2) significantly enhanced human T-cell proliferation in vitro after 5 days of incubation in the absence of mitogen. The activity was completely inhibited by naloxone, an opioid antagonist.
K, Bajpai, V K, Singh, V C, Dhawan, W, Haq, K B, Mathur, S S, Agarwal   +5 more
openaire   +2 more sources

Met-enkephalin effects on associations formed in utero

Peptides, 1982
Rat fetuses exposed to an odor stimulus and an aversive stimulus in utero showed an aversion to the odor when tested 16 days postnatally. Fetuses that also received 80 micrograms/kg Met-enkephalin showed a greater aversion to the odor stimulus than those subjects that did not receive the peptide.
G, Stickrod, D P, Kimble, W P, Smotherman   +2 more
openaire   +2 more sources