Results 81 to 90 of about 14,708 (190)
Macromolecular Rapid Communications, Volume 46, Issue 23, December 5, 2025.Lyotropic Ion‐Specific Effects Drive the Synthesis of Ultra‐Small Protein Nanoparticles via Electrohydrodynamic Jetting. ABSTRACT Protein‐based nanoparticles offer tailored bioactivity and biodegradability that are distinct from their synthetic polymeric counterparts.
Muhammad Haseeb Iqbal +4 more
wiley +1 more source
Toward Structure Prediction for Short Peptides Using the Improved SAAP Force Field Parameters
Journal of Chemistry, 2013 Based on the observation that Ramachandran-type potential energy surfaces of single amino acid units in water are in good agreement with statistical structures of the corresponding amino acid residues in proteins, we recently developed a new all-atom ...
Kenichi Dedachi +3 more
doaj +1 more source
Periaqueductal grey and spinal cord pathology contribute to pain in Parkinson’s disease
npj Parkinson's Disease, 2023 Pain is a key non-motor feature of Parkinson’s disease (PD) that significantly impacts on life quality. The mechanisms underlying chronic pain in PD are poorly understood, hence the lack of effective treatments.
Yazead Buhidma +3 more
doaj +1 more source
Neuropsychopharmacology Reports, Volume 45, Issue 4, December 2025.Delta opioid receptor agonists improved social avoidance, depression, and anxiety‐like symptoms induced by chronic social defeat stress within 14 days of chronic administration. Furthermore, the therapeutic effects were observed earlier than with the existing antidepressant paroxetine (28 days).
Akihisa Tokuda +8 more
wiley +1 more source
Quality Control Strategies for Differentiation of Kalanchoe Species
Phytochemical Analysis, Volume 36, Issue 8, Page 2385-2400, December 2025.ABSTRACT Kalanchoe species products are commercially available in local markets and by internationally accessible online retailers and may exhibit quality issues because of misidentification from similar common names and anatomical similarities among related species used as feedstock. This study proposes an approach using UPLC‐MS/MSE and HPTLC, coupled
Evelyn A. de Andrade +8 more
wiley +1 more source
Monte Carlo Protein Folding: Simulations of Met-Enkephalin with Solvent-Accessible Area Parameterizations [PDF]
, 2003 Treating realistically the ambient water is one of the main difficulties in applying Monte Carlo methods to protein folding. The solvent-accessible area method, a popular method for treating water implicitly, is investigated by means of Metropolis ...
Berg, Bernd A. +2 more
core +2 more sources
The Concise Guide to PHARMACOLOGY 2025/26: G protein‐coupled receptors
British Journal of Pharmacology, Volume 182, Issue S1, Page S24-S151, December 2025.The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +206 more
wiley +1 more source
Molecular Pain, 2008 Background Mice lacking the preproenkephalin (ppENK) gene are hyperalgesic and show more anxiety and aggression than wild-type (WT) mice. The marked behavioral changes in ppENK knock-out (KO) mice appeared to occur in supraspinal response to painful ...
Sun Wei-Zen +3 more
doaj +1 more source
A simple ansatz to describe thermodynamic quantities of peptides and proteins at low temperatures
, 1997 We describe a simple ansatz to approximate the low temperature behavior of proteins and peptides by a mean-field-like model which is analytically solvable.
Philippe de Forcrand +2 more
core +1 more source
Electroacupuncture as a treatment for suspected trigeminal nerve‐mediated head‐shaking in 42 horses
Equine Veterinary Education, Volume 37, Issue 12, Page 647-653, December 2025.Summary Background Electroacupuncture (EA) has been used successfully as a treatment for trigeminal nerve‐mediated head‐shaking (TMHS) in a small case series, but results from a larger number of cases are lacking. Objectives To retrospectively investigate the effectiveness of EA as a treatment for horses with TMHS.
B. Dunkel +5 more
wiley +1 more source