Results 61 to 70 of about 10,961 (170)
Experimental Physiology, Volume 111, Issue 6, Page 2918-2944, 1 June 2026.Abstract The present review aimed to investigate the effectiveness of aerobic exercise (AE) compared to other interventions in decreasing pain intensity and reducing disability in individuals with neck pain. A systematic review (SR) of randomized controlled trials was conducted. This SR was registered in PROSPERO (CRD42021231231).
Ana lzabela Sobral de Oliveira‐Souza +9 more
wiley +1 more source
The effect of Met-enkephalin on mice liver lysosomes
Biomedicine & Pharmacotherapy, 1993 The unsedimentable activities of acid phosphatase (AP) and beta-glucosidase (BG), from mice liver lysosomes significantly increased 6 h after a single i/p injection of Met-enkephalin (MENK). The activity of AP in the serum at the same time remained unchanged.
Šverko, Višnja +4 more
openaire +4 more sources
Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
Annals of Clinical and Translational Neurology, Volume 13, Issue 5, Page 911-923, May 2026.ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Innate Lymphoid Cells in Tissue Homeostasis and Diseases
MedComm, Volume 7, Issue 5, May 2026.Innate lymphoid cells (ILCs) are a heterogeneous group of immune cells with phenotypic and functional plasticity. ILCs dynamically regulate various immune cell types and play a crucial role in the pathophysiological processes of specific organs during sepsis. Targeting ILCs is a promising strategy for treating sepsis.
Zhenzhen Zhan +7 more
wiley +1 more source
In Vivo Regulation of the μ Opioid Receptor: Role of the Endogenous Opioid Agents
Molecular Medicine, 2013 It is well known that genotypic differences can account for the subject-specific responses to opiate administration. In this regard, the basal activity of the endogenous system (either at the receptor or ligand level) can modulate the effects of ...
Veronica Gonzalez-Nunez +3 more
doaj +1 more source
Molecular Pain, 2008 Background Mice lacking the preproenkephalin (ppENK) gene are hyperalgesic and show more anxiety and aggression than wild-type (WT) mice. The marked behavioral changes in ppENK knock-out (KO) mice appeared to occur in supraspinal response to painful ...
Sun Wei-Zen +3 more
doaj +1 more source
Study of Immunotherapy with Endogenous Opiod (Met-Enkephalin) Activated TILs in Fibrosarcoma Induced Balb/C Mice [PDF]
Cell Journal, 2010 Objective: In this study the effects of met-enkephalin on tumor infiltrating lymphocytesfor cancer treatment in fibrosarcoma bearing mice was evaluated.Materials and Methods: Initially, to obtain the most effective dose and treating time forthe ...
Abbas Ali Amini +6 more
doaj
Met-enkephalins in patients with inflammatory bowel diseases
Advances in Medical Sciences, 2011 Opioid peptides provide a link between the neuroendocrine and immune systems. They modify the inflammatory process through their effect on the synthesis and secretion of cytokines and on the proliferation of leukocytes to the inflammatory lesion. The evaluation analyzed changes in free met-enkephalin concentration values in the serum and colon mucosal ...
Owczarek, Danuta +6 more
openaire +3 more sources
针刺研究, 1995 The study was carried out on the animal model of traumatic shock which induced by ligating bilateral hind legs. The contents of enkephalins in-hippocampus, striatum, hypothalarnus. diencephalonand brain stem were determined with radioimmunoassay.
马春红 +3 more
doaj
Clinical Endocrinology, 1981 SUMMARYThirteen patients with either Addison's disease, or Cushing's disease treated by bilateral adrenalectomy, were infused with the long‐acting met‐enkephalin analogue DAMME. In patients with Addison's disease significant and pronounced falls in ACTH and N‐ and C‐terminal β‐LPH were seen; chromatography suggested that β‐endorphin fell concomitantly.
Gaillard, R +4 more
openaire +2 more sources