Results 51 to 60 of about 946,904 (210)
Met Office NWP global model revision history
This page lists the full operational history of the Met Office deterministic global model since the introduction of the UM in 1991. Whilst other sources will contain more detailed information, this page highlights the most significant changes.Previously ...
Unknown
core +1 more source
The gut of silver eels (Anguilla anguilla L.) was investigated in order to describe both the cholinergic and adrenergic intramural innervations, and the localization of possible accessory neuromediators.
C Domeneghini +4 more
doaj +3 more sources
Mycobacteria attenuate nociceptive responses by formyl peptide receptor triggered opioid peptide release from neutrophils. [PDF]
In inflammation, pain is regulated by a balance of pro- and analgesic mediators. Analgesic mediators include opioid peptides which are secreted by neutrophils at the site of inflammation, leading to activation of opioid receptors on peripheral sensory ...
Heike L Rittner +9 more
doaj +1 more source
Innate Lymphoid Cells in Tissue Homeostasis and Diseases
Innate lymphoid cells (ILCs) are a heterogeneous group of immune cells with phenotypic and functional plasticity. ILCs dynamically regulate various immune cell types and play a crucial role in the pathophysiological processes of specific organs during sepsis. Targeting ILCs is a promising strategy for treating sepsis.
Zhenzhen Zhan +7 more
wiley +1 more source
Immunohistochemical methods have been used to investigate the distribution of various opioid peptides derived from mammalian proenkephalin in the central nervous system of Scyliorhinus canicula.
H. Vaudry +7 more
core +1 more source
The control of chronic pain through transplantation of chromaffin cells has been reported over the past few years. Analgesic effects are principally due to the production of opioid peptides and catecholamines by chromaffin cells.
Jean C. Bés +7 more
doaj +1 more source
Chronic Pain: Epidemiology, Pathophysiology, and Clinical Management
The multidimensional nature of chronic pain is illustrated through four interconnected domains. (Left) Epidemiology and Global Burden: Chronic pain affects approximately one in five individuals globally, contributing to a rising trend in disability‐adjusted life years (YLDs) and a significant socioeconomic impact.
Zhihao Shang +12 more
wiley +1 more source
δ-Opioid receptor antagonist inhibits immunomodulation by met-enkephalin analogs
The methionine-enkephalin (Met-enkephalin, Tyr-Gly- Gly-Phe-Met) analogs Tyr-D-Ala-Gly-MePhe-Met NHC3H7- iso (1) and Tyr-D-Ala-Gly-MePhe-Gly-NHC3H7-iso (2) have been shown to enhance human T cell proliferation in in vitro treatment.
Dhawan, Vikas C. +7 more
core +1 more source
The met-enkephalin analogue, D-Ala2-MePhe4-met-enkephalin-(C)-ol (DAMME), was given i.v. to 6 normal subjects. Elevations in plasma prolactin and growth hormone (GH) occurred in association with significant falls in plasma epinephrine and norepinephrine.
Grossman, Ashley +5 more
core +1 more source
Opioids in breast cancer: Between analgesia and modulation of tumour progression
Preclinical investigations consistently demonstrate that activation of μ‐opioid receptors and δ‐opioid receptors promote proliferation, migration, angiogenesis, epithelial‐mesenchymal transition, acquisition of cancer stem cell phenotypes, and chemoresistance.
Marianna Ciwun +2 more
wiley +1 more source

