Results 71 to 80 of about 946,904 (210)
ChemSusChem, Volume 19, Issue 7, 14 April 2026.A rigid, non‐swelling polyacrylate resin enables greener solid‐phase peptide synthesis by allowing various green solvents during the peptide synthesis and significantly reduced process mass intensity without compromising peptide synthesis efficiency/purity.
Sikabwe Noki +9 more
wiley +1 more source
, 1981 Studies were performed to define the responses of plasma met-enkephalin to various endocrine and pathological stimuli and to determine the relationship 0,14656 between plasma β-endorphin and met-enkephalin.
Gaillard, R. +18 more
core +1 more source
Cyclodextrin‐Amino Acid Conjugates: Synthesis and Pharmaceutical Applications
ChemistryEurope, Volume 4, Issue 4, April 2026.Cyclodextrins (CDs) can be combined with amino acids via host‐guest complexation or by covalent conjugation through various synthetic routes. The chemical modifications introduce structural versatility, multifunctionality, and biocompatibility, which are essential characteristics for designing effective, next‐generation pharmaceutical formulations ...
Andrea Cesari +2 more
wiley +1 more source
Failure of Met-Enkephalin to Enhance Natural Killer Cell Activity
, 1991 Several papers have reported the enhancing effects of opiate peptides, like Met-enkephalin, on natural killer (NK) cell activity. We examined the actions of Met-enkephalin on NK activity in blood obtained from 18 different donors, of different ages, many
David S. Chi +7 more
core +1 more source
Comprehensive Physiology, Volume 16, Issue 2, April 2026.Vagus nerve stimulation (VNS) effects span central and peripheral organ systems through diverse mechanistic pathways. This comprehensive review provides a unified synthesis of these mechanisms across neurological, cardiovascular, immunological, metabolic, and gastrointestinal domains, filling a critical gap and serving as a foundational resource for ...
Yifeng Bu +11 more
wiley +1 more source
Unraveling Chronic Pain: From Mechanisms and Risks to Diagnosis and Treatment
MedComm, Volume 7, Issue 4, April 2026.Chronic pain arises through distinct molecular pathways categorized into nociceptive, neuropathic, and nociplastic types. Nociceptive pain begins with TRP channel activation in peripheral nociceptors, signaling via Aδ‐ and C‐fibers through the spinal dorsal horn and spinothalamic tracts to the brain, regulated by descending inhibition and involving ...
Xiaofeng Dai +3 more
wiley +1 more source
Plasma Met-enkephalin and catecholamine responses to intense exercise in humans
, 1992 Native and cryptic Met-enkephalin and catecholamines are coreleased in response to stress. However, it is not known whether Met-enkephalin and catecholamines exhibit concurrent temporal relationships in response to exercise.
K. Pierzchala +4 more
core +1 more source
In Vivo Regulation of the μ Opioid Receptor: Role of the Endogenous Opioid Agents
Molecular Medicine, 2013 It is well known that genotypic differences can account for the subject-specific responses to opiate administration. In this regard, the basal activity of the endogenous system (either at the receptor or ligand level) can modulate the effects of ...
Veronica Gonzalez-Nunez +3 more
doaj +1 more source
Molecular Pain, 2008 Background Mice lacking the preproenkephalin (ppENK) gene are hyperalgesic and show more anxiety and aggression than wild-type (WT) mice. The marked behavioral changes in ppENK knock-out (KO) mice appeared to occur in supraspinal response to painful ...
Sun Wei-Zen +3 more
doaj +1 more source
Study of Immunotherapy with Endogenous Opiod (Met-Enkephalin) Activated TILs in Fibrosarcoma Induced Balb/C Mice [PDF]
Cell Journal, 2010 Objective: In this study the effects of met-enkephalin on tumor infiltrating lymphocytesfor cancer treatment in fibrosarcoma bearing mice was evaluated.Materials and Methods: Initially, to obtain the most effective dose and treating time forthe ...
Abbas Ali Amini +6 more
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