Results 81 to 90 of about 1,366,906 (203)

Studies on circulating met-enkephalin and beta-endorphin: normal subjects and patients with renal and adrenal disease.

open access: yes, 1981
Studies were performed to define the responses of plasma met-enkephalin to various endocrine and pathological stimuli and to determine the relationship 0,14656 between plasma β-endorphin and met-enkephalin.
Gaillard, R.   +18 more
core   +1 more source

Antinociceptive effects of acetyl met-enkephalin derivatives following intrathecal administration in rat [PDF]

open access: yes, 2018
Introduction: Intrathecal infusion of some enkephalin derivatives has been shown to restore analgesia in morphine tolerant patients with less adverse effects such as respiratory depression and constipation compared to morphine.
Rezaiee, Elham   +4 more
core   +1 more source

Failure of Met-Enkephalin to Enhance Natural Killer Cell Activity

open access: yes, 1991
Several papers have reported the enhancing effects of opiate peptides, like Met-enkephalin, on natural killer (NK) cell activity. We examined the actions of Met-enkephalin on NK activity in blood obtained from 18 different donors, of different ages, many
David S. Chi   +7 more
core   +1 more source

Study of Immunotherapy with Endogenous Opiod (Met-Enkephalin) Activated TILs in Fibrosarcoma Induced Balb/C Mice [PDF]

open access: yesCell Journal, 2010
Objective: In this study the effects of met-enkephalin on tumor infiltrating lymphocytesfor cancer treatment in fibrosarcoma bearing mice was evaluated.Materials and Methods: Initially, to obtain the most effective dose and treating time forthe ...
Abbas Ali Amini   +6 more
doaj  

In Vivo Regulation of the μ Opioid Receptor: Role of the Endogenous Opioid Agents

open access: yesMolecular Medicine, 2013
It is well known that genotypic differences can account for the subject-specific responses to opiate administration. In this regard, the basal activity of the endogenous system (either at the receptor or ligand level) can modulate the effects of ...
Veronica Gonzalez-Nunez   +3 more
doaj   +1 more source

Plasma Met-enkephalin and catecholamine responses to intense exercise in humans

open access: yes, 1992
Native and cryptic Met-enkephalin and catecholamines are coreleased in response to stress. However, it is not known whether Met-enkephalin and catecholamines exhibit concurrent temporal relationships in response to exercise.
K. Pierzchala   +4 more
core   +1 more source

Differential regulation of morphine antinociceptive effects by endogenous enkephalinergic system in the forebrain of mice

open access: yesMolecular Pain, 2008
Background Mice lacking the preproenkephalin (ppENK) gene are hyperalgesic and show more anxiety and aggression than wild-type (WT) mice. The marked behavioral changes in ppENK knock-out (KO) mice appeared to occur in supraspinal response to painful ...
Sun Wei-Zen   +3 more
doaj   +1 more source

Plasma met-enkephalin, beta-endorphin and leu-enkephalin levels in human hepatic encephalopathy

open access: yes, 2007
257-265To address the role of the opioid system in the pathogenesis of hepatic encephalopathy [HE] we measured plasma met- enkephalin, beta -endorphin and leu- enkephalin in patients with different grades of HE compared to control subjects and patients ...
El Khayat, H.   +4 more
core  

Met-enkephalins in patients with inflammatory bowel diseases

open access: yesAdvances in Medical Sciences, 2011
Opioid peptides provide a link between the neuroendocrine and immune systems. They modify the inflammatory process through their effect on the synthesis and secretion of cytokines and on the proliferation of leukocytes to the inflammatory lesion. The evaluation analyzed changes in free met-enkephalin concentration values in the serum and colon mucosal ...
Owczarek, Danuta   +6 more
openaire   +3 more sources

The lipolytic activity of met-enkephalin, leu-enkephalin, morphine, methadone and naloxone in human adipose tissue

open access: yes, 1981
Met-enkephalin and Leu-enkephalin lipolytic activity in human omental adipose tissue is compared with that of morphine, methadone and naloxone. Met- and leu-enkephalin exhibited lipolytic action similar to that of morphine but unlike that of methadone ...
NENCINI, Paolo, PAROLI, Eugenio
core  

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