Results 81 to 90 of about 946,904 (210)
Similarity of Ca2+-bound conformations of morphine and Met-enkephalin: A computational study
The conformations of the free and Ca2+-bound forms of morphine and Met-enkephalin were compared based on an earlier proposal that extracellular Ca2+ may dictate the bioactive conformations of peptide hormones and drugs.
Ananthanarayanan, Vettai S. +1 more
core +1 more source
Met-enkephalins in patients with inflammatory bowel diseases
Opioid peptides provide a link between the neuroendocrine and immune systems. They modify the inflammatory process through their effect on the synthesis and secretion of cytokines and on the proliferation of leukocytes to the inflammatory lesion. The evaluation analyzed changes in free met-enkephalin concentration values in the serum and colon mucosal ...
Owczarek, Danuta +6 more
openaire +3 more sources
Met-enkephalin and Leu-enkephalin lipolytic activity in human omental adipose tissue is compared with that of morphine, methadone and naloxone. Met- and leu-enkephalin exhibited lipolytic action similar to that of morphine but unlike that of methadone ...
NENCINI, Paolo, PAROLI, Eugenio
core
The study was carried out on the animal model of traumatic shock which induced by ligating bilateral hind legs. The contents of enkephalins in-hippocampus, striatum, hypothalarnus. diencephalonand brain stem were determined with radioimmunoassay.
马春红 +3 more
doaj
Cytogenetic Effects of Met-enkephalin (Peptid-M) on Human Lymphocytes
The structure, complementary structure and cytogenetic/proliferative effects of the Met-enkephalin on human peripheral blood lymphocytes were analyzed. Met-enkephalin, i.e.
Branka Marušić-Della Marina +41 more
core
The effect of Met-enkephalin on mice liver lysosomes
The unsedimentable activities of acid phosphatase (AP) and beta-glucosidase (BG), from mice liver lysosomes significantly increased 6 h after a single i/p injection of Met-enkephalin (MENK). The activity of AP in the serum at the same time remained unchanged.
Šverko, Višnja +4 more
openaire +4 more sources
Protective Effects of Met-enkephalin on Alcohol Induced Gastric Lesions
The model of ethanol induced gastric lesions is useful in the evaluation of gastric cytoprotection. We used it to measure cytoprotective effects of two neuropeptides, Met-enkephalin (Peptid-M, LUPEX®) and α-melanocyte stimulating hormone (&alpha ...
Štambuk, Nikola +17 more
core
У щурів в динаміці експеріментального діабету імунофлюоресцентним методом в суб’ядрах паравентрикулярного ядра вивчено розподіл нейронів, що синтезують мет-енкефалін.
Абрамов, А.В. +1 more
core +2 more sources
SUMMARYThirteen patients with either Addison's disease, or Cushing's disease treated by bilateral adrenalectomy, were infused with the long‐acting met‐enkephalin analogue DAMME. In patients with Addison's disease significant and pronounced falls in ACTH and N‐ and C‐terminal β‐LPH were seen; chromatography suggested that β‐endorphin fell concomitantly.
Gaillard, R +4 more
openaire +2 more sources
Introduction: Intrathecal infusion of some enkephalin derivatives has been shown to restore analgesia in morphine tolerant patients with less adverse effects such as respiratory depression and constipation compared to morphine.
Rezaiee, Elham +4 more
core +1 more source

