Results 81 to 90 of about 14,564 (138)
Recent Developments in Capillary and Microchip Electroseparations of Peptides (2023–mid 2025)
ELECTROPHORESIS, Volume 47, Issue 1, Page 106-136, January 2026.ABSTRACT This review presents a comprehensive overview of the developments and applications of high‐performance capillary and microchip electromigration methods (zone electrophoresis in a free solution or in sieving media, isotachophoresis, isoelectric focusing, affinity electrophoresis, electrokinetic chromatography, and electrochromatography) for ...
Václav Kašička
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Movement Disorders, Volume 41, Issue 1, Page 95-106, January 2026.Abstract Background Huntington's disease (HD) is characterized by early, selective, progressive vulnerability of striatal medium spiny neurons (MSNs). Proenkephalin (PENK), a precursor of opioid peptides abundantly expressed in MSNs, is a promising biomarker of striatal integrity, but region‐specific associations and its potential for early‐stage ...
Mena Farag +14 more
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Nitrous Oxide: Mechanism of Its Antinociceptive Action [PDF]
, 1995 Nitrous oxide (N2O) is an anesthetic gas known to produce an analgesic effect at sub-anesthetic concentrations. This analgesic property of N2O can be clinically exploited in a broad range of conditions where pain relief is indicated.
Quock, Raymond M., Vaughn, Linda K.
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Pain Research and Management, Volume 2026, Issue 1, 2026.Advanced cancer continues to pose a substantial global challenge, with complex symptom burdens and limited therapeutic options. Traditional Chinese Medicine (TCM), grounded in holistic theory and the principles of syndrome differentiation, employs interventions such as herbal medicine, acupuncture, moxibustion, and acupoint‐based therapies to address ...
Chunmeng Jiao +6 more
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Pain Research and Management, Volume 2026, Issue 1, 2026.Objective To examine the effects of music therapy, inhalation aromatherapy, and their combination on pain intensity, anxiety, and fear in patients undergoing coronary angiography. Methods This randomized controlled trial included 128 patients assigned to four groups: control, music therapy, aromatherapy, and combined music + aromatherapy. Interventions
Fatma Gür +2 more
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Molecular Pain, 2008 Background Mice lacking the preproenkephalin (ppENK) gene are hyperalgesic and show more anxiety and aggression than wild-type (WT) mice. The marked behavioral changes in ppENK knock-out (KO) mice appeared to occur in supraspinal response to painful ...
Sun Wei-Zen +3 more
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In Vivo Regulation of the μ Opioid Receptor: Role of the Endogenous Opioid Agents
Molecular Medicine, 2013 It is well known that genotypic differences can account for the subject-specific responses to opiate administration. In this regard, the basal activity of the endogenous system (either at the receptor or ligand level) can modulate the effects of ...
Veronica Gonzalez-Nunez +3 more
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Study of Immunotherapy with Endogenous Opiod (Met-Enkephalin) Activated TILs in Fibrosarcoma Induced Balb/C Mice [PDF]
Cell Journal, 2010 Objective: In this study the effects of met-enkephalin on tumor infiltrating lymphocytesfor cancer treatment in fibrosarcoma bearing mice was evaluated.Materials and Methods: Initially, to obtain the most effective dose and treating time forthe ...
Abbas Ali Amini +6 more
doaj
Monte Carlo Protein Folding: Simulations of Met-Enkephalin with Solvent-Accessible Area Parameterizations [PDF]
, 2003 Treating realistically the ambient water is one of the main difficulties in applying Monte Carlo methods to protein folding. The solvent-accessible area method, a popular method for treating water implicitly, is investigated by means of Metropolis ...
Berg, Bernd A. +2 more
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Unfolding Hidden Barriers by Active Enhanced Sampling
, 2017 Collective variable (CV) or order parameter based enhanced sampling algorithms have achieved great success due to their ability to efficiently explore the rough potential energy landscapes of complex systems.
Chen, Ming, Zhang, Jing
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