Results 51 to 60 of about 931,154 (348)
Molecular Oncology, EarlyView.mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo +8 more
wiley +1 more source
Addressing the evidence to practice gap for complex interventions in primary care : a systematic review of reviews protocol [PDF]
, 2014 Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.Peer reviewedPublisher ...
Addington +17 more
core +3 more sources
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
Re-expressing coefficients from regression models for inclusion in a meta-analysis
BMC Medical Research MethodologyMeta-analysis poses a challenge when original study results have been expressed in a non-uniform manner, such as when regression results from some original studies were based on a log-transformed key independent variable while in others no transformation
Matthew W. Linakis +3 more
doaj +1 more source
International Brazilian Journal of Urology, 2012 Objective To perform a systematic review and meta-analysis of all randomized controlled trials comparing the efficacy of Sipuleucel-T versus placebo for asymptomatic or minimally symptomatic metastatic castration-refractory prostate cancer (mCRPC).
Tobias Engel Ayer Botrel +6 more
doaj +1 more source
Topical anti-inflammatory treatments for eczema: network meta-analysis
Cochrane Database of Systematic ReviewsEczema (atopic dermatitis) is the most burdensome skin condition worldwide and cannot currently be prevented or cured. Topical anti-inflammatory treatments are used to control eczema symptoms, but there is uncertainty about the relative effectiveness and safety of different topical anti-inflammatory treatments.To compare and rank the efficacy and ...
Lax, SJ +16 more
openaire +3 more sources
Topography of Generically Folded Spacecapes: Towards a Cognitive Metatheory in Architectural Design [PDF]
, 2017 If we visualize philosophy as a science of the sciences (in the tradition of Hans Heinz Holz), then theories within the philosophical framework are always meta-theories of the respective field of interest in question with which philosophy is actually ...
Koutsandrea, Kanelia +1 more
core +1 more source
, 2018 CDNs have reshaped the Internet architecture at large. They operate (globally) distributed networks of servers to reduce latencies as well as to increase availability for content and to handle large traffic bursts.
Hohlfeld, Oliver +3 more
core +1 more source
A Topic Recommender for Journalists [PDF]
, 2018 The way in which people acquire information on events and form their own opinion on them has changed dramatically with the advent of social media. For many readers, the news gathered from online sources become an opportunity to share points of view ...
Cucchiarelli, Alessandro +3 more
core +1 more source
Molecular Oncology, EarlyView.RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha +10 more
wiley +1 more source