Results 81 to 90 of about 974,024 (326)
FEBS Open Bio, EarlyView.The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman +4 more
wiley +1 more source
CALIDAD DE VIDA RELACIONADA CON LA SALUD EN TUBERCULOSIS: REVISIÓN SISTEMÁTICA Y METANÁLISIS
Infectio, 2018 Objective: To perform a metanalysis on the effect of the tuberculosis on the dimensions of the SF-36. Methods: Systematic review and meta-analysis, following the PRISMA guide.
Natalia Giraldo
doaj +1 more source
Journal of Clinical MedicineBackground: Periodontitis and diabetes mellitus (DM) exhibit a bidirectional relationship and are globally significant systemic chronic conditions. The utilization of antibiotics alongside non-surgical periodontal treatment (NSPT) has been a subject of investigation in numerous clinical studies involving human subjects.
Rafael Scaf de Molon +5 more
openaire +2 more sources
Can meta-analysis be trusted? [PDF]
, 2003 Until around 25 years ago the only way to assimilate and evaluate research evidence was through discursive literature reviews, in which someone with an interest in a given research topic would accumulate and subjectively evaluate the importance of ...
Field, Andy P
core +1 more source
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
How reliable are systematic reviews in empirical software engineering? [PDF]
, 2010 BACKGROUND – the systematic review is becoming a more commonly employed research instrument in empirical software engineering. Before undue reliance is placed on the outcomes of such reviews it would seem useful to consider the robustness of the ...
Kitchenham, BA +3 more
core +2 more sources
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Archives of Academic Emergency Medicine, 2019 Introduction: Hospitals are the most important infrastructures of any society. The hospital emergency department is one of the most important wards of hospitals in response to disasters.
Mosayeb Kazemzadeh +4 more
doaj +1 more source
Linking families with pre-school children from healthcare services to community resources: a systematic review protocol [PDF]
, 2017 Background: Poor health and health inequalities persist despite increasing investment in health improvement programmes across high-income countries. Evidence suggests that to reduce health inequalities, a range of activities targeted at different ...
Burns, Jacky +3 more
core +6 more sources