Results 201 to 210 of about 993,269 (287)

Large language models for risk-of-bias assessment in randomised clinical trials-a comparative validation study. [PDF]

open access: yesEBioMedicine
Nyrhi L   +7 more
europepmc   +1 more source

Eye-tracking as a lens into meta-reasoning

open access: yesThinking & Reasoning
Snehal Dhengre   +2 more
openaire   +1 more source

To What Extent Do Australian Government Metrics Align With Indigenous and Non‐Indigenous Conceptualisations of Wellbeing? A Scoping Review of Wellbeing Frameworks

open access: yesAustralian Journal of Social Issues, EarlyView.
ABSTRACT Indigenous wellbeing theories offer potential to better measure social and cultural determinants. This scoping review aimed to identify the types of metrics used by the Australian government to assess wellbeing and evaluate the alignment of current frameworks against Indigenous and non‐Indigenous conceptualisations of wellbeing.
Sophie Wright‐Pedersen   +5 more
wiley   +1 more source

A Crystalline and Thermally Stable Selenocysteine Selenenic Acid

open access: yesAngewandte Chemie, EarlyView.
The long‐sought catalytic intermediate of selenoproteins, selenocysteine selenenic acid (Sec–SeOH), is isolated for the first time at ambient temperature. A bioinspired selenopeptide sequence encapsulated within a protective molecular cradle and an oxidant‐free route from selenenyl iodide (Sec–SeI) enable the isolation of Sec–SeOH. Contrary to the long‐
Ryosuke Masuda, Satoru Kuwano, Kei Goto
wiley   +2 more sources

Animal models in molecular biology research: Challenges, ethical imperatives, and the path to human‐relevant translation

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The graphical abstract shows how molecular biology research has shifted from using traditional animal models toward using methods that are more relevant to humans. It points out the main problems, differences between species, difficulty in reproducing results, moral issues, and lack of infrastructure that make translational accuracy harder to achieve ...
Md. Shajid Hossain Rafi   +6 more
wiley   +1 more source

1,7‐Digallatetracarborane: Between Nucleophilic closo‐Cluster and “Inverse Sandwich” Digallylene

open access: yesAngewandte Chemie, EarlyView.
A dianionic π‐ligand is used to make a Janus‐type twofold complex with low‐valent gallium Ga(+I). The resulting compound can be seen as and reveals the reactivity of both: a Wade‐type closo‐carborane cluster with nucleophilic Ga‐sites, as well as π‐ligand stabilized Ga(I) atoms in an inverse sandwich compound.
Julijan Sarcevic   +4 more
wiley   +2 more sources

An Enantioselective Alkene Aminoarylation to Form Chiral Indolines via Electrostatically‐Directed Palladium Catalysis

open access: yesAngewandte Chemie, EarlyView.
Enantioselective aminoarylation of ortho‐allyl anilines is achieved under mild conditions. Key to success is the electrostatically‐directed nature of the key aminopalladation step, achieved by using the sulfonated chiral ligand sSPhos on palladium. A detailed study of electronic trends allows tuning of the sulfonamide protecting group to enable good ...
Max Kadarauch   +4 more
wiley   +2 more sources

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