Results 31 to 40 of about 473 (109)

Troubleshooting in Large-Scale LC-ToF-MS Metabolomics Analysis: Solving Complex Issues in Big Cohorts

open access: yesMetabolites, 2019
Metabolomics, understood as the science that manages the study of compounds from the metabolism, is an essential tool for deciphering metabolic changes in disease.
Juan Rodríguez-Coira   +9 more
doaj   +1 more source

Antimicrobial activity and phenolic composition of varieties of Hibiscus sabdariffa L. with red and white calyces

open access: yesCyTA - Journal of Food, 2023
The antibacterial activities (ABAC) of white calyces varieties (WCV) of Hibiscus sabdariffa L has not been explored in depth. The aims of the study were to determine the ABAC of WCV and the relationship of phenolic composition with ABAC.
Yolanda Salinas-Moreno   +5 more
doaj   +1 more source

Molecular Signatures and Functional Pathways of Human Monocytes and Macrophages in Allergy: An EAACI AllergoOncology Scoping Review

open access: yesAllergy, Volume 80, Issue 10, Page 2710-2725, October 2025.
ABSTRACT AllergoOncology explores the intersection of allergic diseases and cancer, focusing on shared immune mechanisms. While monocytes and macrophages are extensively studied in cancer, their roles in allergic diseases remain underexplored. To address this gap, we conducted a scoping review to systematically characterize the molecular landscape and ...
Rodolfo Bianchini   +30 more
wiley   +1 more source

Medicina de precisión y medicina basada en la evidencia

open access: yesRevista Cubana de Medicina Militar, 2019
El médico en la práctica clínica, asiste con frustración a la ausencia de una metodología uniforme y estandarizada, para procesar la gran avalancha de datos clínicos. Se ve envuelto en un proceso de toma de decisiones en condiciones de incertidumbre.
José Miguel Rodríguez Perón
doaj  

METABOLÔMICA MICROBIANA: INOVAÇÕES E APLICAÇÕES

open access: yesQuímica Nova
Over the past few years, metabolomics has been employed in a broad range of applications in different research fields. Microbial metabolomics has been applied in several microbiological areas, such as identification of microorganisms, cell mutations ...
João Raul Belinato   +4 more
doaj   +1 more source

Prognostic biomarkers of Parkinson’s disease in the Spanish EPIC cohort: a multiplatform metabolomics approach

open access: yesnpj Parkinson's Disease, 2021
The lack of knowledge about the onset and progression of Parkinson’s disease (PD) hampers its early diagnosis and treatment. Metabolomics might shed light on the PD imprint seeking a broader view of the biochemical remodeling induced by this disease in ...
Carolina Gonzalez-Riano   +12 more
doaj   +1 more source

Identifying subgroups of childhood obesity by using multiplatform metabotyping

open access: yesFrontiers in Molecular Biosciences, 2023
Introduction: Obesity results from an interplay between genetic predisposition and environmental factors such as diet, physical activity, culture, and socioeconomic status.
David Chamoso-Sanchez   +8 more
doaj   +1 more source

Differential abundance of lipids and metabolites related to SARS-CoV-2 infection and susceptibility

open access: yesScientific Reports, 2023
The mechanisms driving SARS-CoV-2 susceptibility remain poorly understood, especially the factors determining why unvaccinated individuals remain uninfected despite high-risk exposures.
Oihane E. Albóniga   +12 more
doaj   +1 more source

Endogenous rhythmic growth and ectomycorrhizal fungi modulate priming of antiherbivore defences in subsequently formed new leaves of oak trees

open access: yesJournal of Ecology, Volume 113, Issue 6, Page 1382-1396, June 2025.
A first herbivore attack primes direct and indirect defences of newly formed oak leaves and, the specific display of defence priming is regulated by rhythmic growth, and modulated by the interaction with the ectomycorrhizal fungus Piloderma croceum. Therefore, the priming memory in oaks can be transmitted to the next growth cycle. GC, growth cycle; SF,
I. Fernández   +8 more
wiley   +1 more source

Breaking into nature's secret medicine cabinet: lichens – a biochemical goldmine ready for discovery

open access: yesNew Phytologist, Volume 246, Issue 2, Page 437-449, April 2025.
Summary Secondary metabolites are a crucial source of bioactive compounds playing a key role in the development of new pharmaceuticals. Recently, biosynthetic research has benefited significantly from progress on various fronts, including reduced sequencing costs, improved genome/metabolome mining strategies, and expanding tools/databases to compare ...
Garima Singh   +3 more
wiley   +1 more source

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