Results 41 to 50 of about 3,357 (158)

Linfangiogénese no tecido adiposo em ratinhos e sua relação com a obesidade: Avaliação histoquímica e metabolómica (lipidómica) mediante UPLC-MS/MS [PDF]

, 2011
Introdução: O tecido adiposo é um órgão endócrino dinâmico, secretando factores importantes na regulação do metabolismo lipídico, do fluxo vascular sanguíneo e linfático e função imunológica, entre outros.
Almeida, Joana, Fernandes, Rúben, Macedo, Bárbara, Prudêncio, Cristina, Ramalho, Renata, Soares, Raquel   +5 more
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Endogenous rhythmic growth and ectomycorrhizal fungi modulate priming of antiherbivore defences in subsequently formed new leaves of oak trees

Journal of Ecology, Volume 113, Issue 6, Page 1382-1396, June 2025.
A first herbivore attack primes direct and indirect defences of newly formed oak leaves and, the specific display of defence priming is regulated by rhythmic growth, and modulated by the interaction with the ectomycorrhizal fungus Piloderma croceum. Therefore, the priming memory in oaks can be transmitted to the next growth cycle. GC, growth cycle; SF,
I. Fernández, M. L. Bouffaud, A. Martínez‐Medina, M. Schädler, M. T. Tarkka, A. Weinhold, N. M. van Dam, S. Herrmann, F. Buscot   +8 more
wiley   +1 more source

Medicina de precisión y medicina basada en la evidencia

Revista Cubana de Medicina Militar, 2019
El médico en la práctica clínica, asiste con frustración a la ausencia de una metodología uniforme y estandarizada, para procesar la gran avalancha de datos clínicos. Se ve envuelto en un proceso de toma de decisiones en condiciones de incertidumbre.
José Miguel Rodríguez Perón
doaj  

Prognostic biomarkers of Parkinson’s disease in the Spanish EPIC cohort: a multiplatform metabolomics approach

npj Parkinson's Disease, 2021
The lack of knowledge about the onset and progression of Parkinson’s disease (PD) hampers its early diagnosis and treatment. Metabolomics might shed light on the PD imprint seeking a broader view of the biochemical remodeling induced by this disease in ...
Carolina Gonzalez-Riano, Jorge Saiz, Coral Barbas, Alberto Bergareche, José Mª Huerta, Eva Ardanaz, Marcela Konjevod, Elisabet Mondragon, M. E. Erro, M. Dolores Chirlaque, Eunate Abilleira, Fernando Goñi-Irigoyen, Pilar Amiano   +12 more
doaj   +1 more source

Los telómeros y el origen de la enfermedad [PDF]

, 2016
Este artículo recoge la presentación que la autora llevó a cabo de su carrera científica en el Foro de Encuentros, en Madrid, en Febrero de 2016En el presente texto se recoge la descripción de la trayectoria científica de María A.
Blasco, María A.
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Breaking into nature's secret medicine cabinet: lichens – a biochemical goldmine ready for discovery

New Phytologist, Volume 246, Issue 2, Page 437-449, April 2025.
Summary Secondary metabolites are a crucial source of bioactive compounds playing a key role in the development of new pharmaceuticals. Recently, biosynthetic research has benefited significantly from progress on various fronts, including reduced sequencing costs, improved genome/metabolome mining strategies, and expanding tools/databases to compare ...
Garima Singh, Francesco Dal Grande, Francis M. Martin, Marnix H. Medema   +3 more
wiley   +1 more source

The reaction mechanism of metallo-beta-lactamases is tuned by the conformation of an active site mobile loop [PDF]

, 2018
Carbapenems are "last resort" β-lactam antibiotics used to treat serious and life-threatening health care-associated infections caused by multidrug-resistant Gram-negative bacteria.
Alzari, Pedro M., Bethel, Christopher R., Bonomo, Robert A., Giannini, Estefanía, Klinke, Sebastian, Llarrull, Leticia Irene, Mojica, María F., Otero, Lisandro Horacio, Palacios, Antonela Rocio, Taracila, Magdalena A., Vila, Alejandro Jose   +10 more
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Anticancer and Antioxidant Activities of Rhizospheric Soil Bacteria of Lophocereus marginatus

International Journal of Microbiology, Volume 2025, Issue 1, 2025.
Identification of new sources of compounds with anticancer and antioxidant potential is essential for cancer treatment. Rhizospheric bacteria have emerged as a promising source of these agents. This study is aimed at investigating the anticancer and antioxidant properties of bacteria isolated from the rhizosphere of Lophocereus marginatus.
Jesica María Ramírez-Villalobos, César Iván Romo-Sáenz, Ramiro Quintanilla-Licea, Patricia Tamez-Guerra, Orquídea Pérez-González, José Roberto Estupiñan-Jiménez, Ángel David Torres-Hernández, Nancy Edith Rodríguez-Garza, Cristina Rodríguez-Padilla, Ricardo Gomez-Flores, Ram Prasad   +10 more
wiley   +1 more source

Differential abundance of lipids and metabolites related to SARS-CoV-2 infection and susceptibility

Scientific Reports, 2023
The mechanisms driving SARS-CoV-2 susceptibility remain poorly understood, especially the factors determining why unvaccinated individuals remain uninfected despite high-risk exposures.
Oihane E. Albóniga, Elena Moreno, Javier Martínez-Sanz, Pilar Vizcarra, Raquel Ron, Jorge Díaz-Álvarez, Marta Rosas Cancio-Suarez, Matilde Sánchez-Conde, Juan Carlos Galán, Santiago Angulo, Santiago Moreno, Coral Barbas, Sergio Serrano-Villar   +12 more
doaj   +1 more source

Validación de los datos obtenidos en un análisis genómico y metabolómico de un modelo animal de sobreexpresión de la COX-2 en hígado [PDF]

, 2013
Trabajo final de Master: "Aproximaciones Moleculares en ciencias de la salud": 42 p. figuras y tablas[EN] Expression of cyclooxygenase 2 (COX-2) in hepatocytes is limited to those situations where occurs dedifferentiation or proliferation as regeneration
Ovejero Martínez, Tamara
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