Results 31 to 40 of about 172,525 (164)

Apolipoprotein E content of VLDL limits LPL-mediated triglyceride hydrolysis

open access: yesJournal of Lipid Research, 2022
High levels of circulating triglycerides (TGs), or hypertriglyceridemia, are key components of metabolic diseases, such as type 2 diabetes, metabolic syndrome, and CVD.
Brynne E. Whitacre   +5 more
doaj   +1 more source

Concentrically Encapsulated Dual-Enzyme Capsules for Synergistic Metabolic Disorder Redressing and Cytotoxic Intermediates Scavenging

open access: yesNanomaterials, 2022
Enzyme therapy has important implications for the treatment of metabolic disorders and biological detoxification. It remains challenging to prepare enzymatic nanoreactors with high therapeutic efficiency and low emission of cytotoxic reaction ...
Chao Deng   +3 more
doaj   +1 more source

Plasma kinetics of an LDL-like nanoemulsion and lipid transfer to HDL in subjects with glucose intolerance

open access: yesClinics, 2012
OBJECTIVE: Glucose intolerance is frequently associated with an altered plasma lipid profile and increased cardiovascular disease risk. Nonetheless, lipid metabolism is scarcely studied in normolipidemic glucose-intolerant patients. The aim of this study
Marina P Bertato   +4 more
doaj   +1 more source

Pharmacokinetic study on the interaction between succinic acid and irbesartan in rats and its potential mechanism

open access: yesPharmaceutical Biology, 2021
Context Succinic acid and irbesartan are commonly used drugs in cardiovascular disease treatment. The interaction might occur during their co-administration, which was still unclear.
Yongpeng Wang   +3 more
doaj   +1 more source

A study of estrogen metabolic clearance rates and transfer factors [PDF]

open access: yesJournal of Clinical Investigation, 1969
We have attempted to measure the metabolic clearance rates (MCR) and the transfer factors of estradiol (E(2)) and estrone (E(1)) during 2-hr and 12-hr infusions. When estradiol-(3)H was infused for 2 hr, apparent equilibrium was reached at 70 min; the 12-hr infusions showed that plasma estradiol-(3)H levels increased slowly throughout the infusion ...
W C, Hembree, C W, Bardin, M B, Lipsett
openaire   +2 more sources

Brain Fluid Clearance After Traumatic Brain Injury Measured Using Dynamic Positron Emission Tomography

open access: yesNeurotrauma Reports
Brain fluid clearance by pathways including the recently described paravascular glymphatic system is a critical homeostatic mechanism by which metabolic products, toxins, and other wastes are removed from the brain.
Tracy Butler   +17 more
doaj   +3 more sources

The role of brown adipose tissue in branched-chain amino acid clearance in people

open access: yesiScience
Summary: Brown adipose tissue (BAT) in rodents appears to be an important tissue for the clearance of plasma branched-chain amino acids (BCAAs) contributing to improved metabolic health.
Yasser G. Abdelhafez   +11 more
doaj   +1 more source

Flexibility of Physiological Traits Underlying Inter-Individual Growth Differences in Intertidal and Subtidal Mussels Mytilusgalloprovincialis. [PDF]

open access: yesPLoS ONE, 2016
Mussel seed (Mytilusgalloprovincialis) gathered from the intertidal and subtidal environments of a Galician embayment (NW, Spain) were maintained in the laboratory during five months to select fast (F) and slow (S) growing mussels.
María José Fernández-Reiriz   +2 more
doaj   +1 more source

Choroid plexus-mediated CSF secretion remains stable in aging rats via high and age-resistant metabolic activity

open access: yesNature Communications
Our brain is bathed in cerebrospinal fluid (CSF) that is produced by the choroid plexus. CSF serves as a dispersion route for hormones and nutrients, and a conduit for waste clearance.
Sara D. Lolansen   +14 more
doaj   +1 more source

Lactate clearance predicts outcome after major trauma

open access: yesAfrican Journal of Emergency Medicine, 2014
To determine a correlation between lactate clearance within 48 h and survival in trauma patients at a Level I trauma centre in a developing country and compare to previous international lactate clearance studies.
Essi Heinonen   +3 more
doaj   +1 more source

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