Results 141 to 150 of about 1,774 (249)

Proteomic Analysis Reveals Accompanying Anion‐Dependent Changes of Cadmium Toxicity During Arabidopsis thaliana Development

open access: yesPlant, Cell &Environment, Volume 49, Issue 4, Page 2069-2079, April 2026.
ABSTRACT Cadmium (Cd) is a significant environmental pollutant with widespread detrimental effects on living organisms, making it a frequent subject of laboratory studies. However, different types of Cd salts are used to spike media, often without considering the possibility that accompanying anions may influence the effects of metal cations. Using two
Martin Lyčka   +6 more
wiley   +1 more source

Psoriasis, stem cells, and obesity: metabolic exploration for therapeutics. [PDF]

open access: yesJ Med Life
Constantin C   +6 more
europepmc   +1 more source

Methylglyoxal Affects Dopamine Homeostasis in SH‐SY5Y Cells Through the Modulation of miR‐190a and miR‐214

open access: yesThe FASEB Journal, Volume 40, Issue 5, 15 March 2026.
In SH‐SY5Y cells, Methylglyoxal (MGO) reduces the intracellular dopamine content, up‐regulating the expression of proteins that modulate dopamine amount (MAO‐B, COMT, and α‐Syn). The MGO‐induced increase of COMT and α‐Syn expression is mediated by the reduction of miR‐214 and miR‐190a levels.
Alessandra Croce   +9 more
wiley   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

open access: yesAging and Cancer, Volume 7, Issue 1, Page 21-31, March 2026.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

PCSK7 levels in women with and without PCOS. [PDF]

open access: yesJ Clin Transl Endocrinol
Atkin SL   +3 more
europepmc   +1 more source

Dysfunctional TRIM31 of POMC Neurons Provokes Hypothalamic Injury and Peripheral Metabolic Disorder under Long‐Term Fine Particulate Matter Exposure

open access: yesAdvanced Science, Volume 13, Issue 14, 9 March 2026.
Particulate matter ≤2.5 µm (PM2.5) elevates risks of neurological and chronic metabolic diseases, but the underlying mechanisms linking PM2.5‐induced central nervous system (CNS) injury to metabolic dysfunction remain unclear. Hypothalamic pro‐opiomelanocortin‐expressing (POMC+) neurons regulate systemic metabolic homeostasis, and tripartite motif ...
Chenxu Ge   +21 more
wiley   +1 more source

The Circadian Modulators as Molecular Targets in Cancer-A Review. [PDF]

open access: yesInt J Mol Sci
Wolniakowska A   +3 more
europepmc   +1 more source

Mitophagy and Ubiquitination Coordinate Context‐Specific Mitochondrial Quality Control and EMT/MET Plasticity to Drive Cancer Cell Invasion

open access: yesAdvanced Science, Volume 13, Issue 16, 18 March 2026.
Metastatic invasion emerges when tumor‐intrinsic programs and microenvironmental forces converge on mitochondrial quality control. A context‐stratified framework links mtROS, mtDNA integrity, mechanics and nutrient/oxygen cues to fission–fusion remodeling, mtUPR and mitophagy.
Bin‐Hsu Mao   +3 more
wiley   +1 more source

Single-cell genomics highlight MYC-associated metabolic activation and altered cell interactions in T-prolymphocytic leukemia progression. [PDF]

open access: yesNat Commun
Wahnschaffe L   +25 more
europepmc   +1 more source

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