ABSTRACT Most cancer cells rely on aerobic glycolysis to support uncontrolled proliferation and evade apoptosis and switch to glutamine metabolism to survive under hypoxic conditions. In hepatocellular carcinoma (HCC), the Wnt/β‐catenin pathway acts as a critical driver of metabolic reprogramming and stemness, primarily by enhancing aerobic glycolysis ...
Sanjit K. Roy +5 more
wiley +1 more source
Metabolomic Insights into the Phytochemical Profiles and Seasonal Shifts of <i>Fucus serratus</i> and <i>F. vesiculosus</i> Harvested in Danish Coastal Waters (Aarhus Bay)-An Untargeted High-Resolution Mass-Spectrometry Approach. [PDF]
Curtasu MV +4 more
europepmc +1 more source
In vitro, low‐density lipoprotein cholesterol (LDL cholesterol) promotes the accumulation of lipid derivatives in astrocytes. Additionally, LDL cholesterol exposure causes a decrease in the expression of low‐density lipoprotein receptor (LDLr), 3‐hydroxy‐3‐methylglutaryl‐CoA reductase (HMGCR), and sterol regulatory element‐binding transcription factor ...
Gabriela Joras Baumart +15 more
wiley +1 more source
Cytoskeleton Remodeling-Related Proteins Represent a Specific Salivary Signature in PSC Patients. [PDF]
Ceccherini E +7 more
europepmc +1 more source
ABSTRACT Background The packaging and marketing of electronic cigarettes (e‐cigs) often target younger demographics. This study aimed to evaluate gene expression in e‐cig users through exfoliative cytology. Methods Samples were collected from 17 e‐cig users and 10 nonsmokers as controls.
Alba Pérez‐Jardón +10 more
wiley +1 more source
Clustering-based identification of immune-related gene signatures in hepatocellular carcinoma. [PDF]
Brahmaiah J +3 more
europepmc +1 more source
The power of ionic movements in plants
Summary The movement of ion‐driven electrogenic events known as plant action potentials in the Venus flytrap Dionaea muscipula has first been recognized in Darwin's time. Besides electrophysiological techniques making use of current‐ and voltage‐recording electrodes, today an ever‐growing spectrum of tools has become available, that report online ...
Rainer Hedrich, Ines Kreuzer
wiley +1 more source
From Metabolic to Epigenetic Memory: The Impact of Hyperglycemia-Induced Epigenetic Signature on Kidney Disease Progression and Complications. [PDF]
Cannito S +6 more
europepmc +1 more source
Molecular interplay of ASNS and the PI3K-AKT-mTOR pathway in CMV and HIV co-infections: Therapeutic implications. [PDF]
Zhang H +9 more
europepmc +1 more source
Unraveling the pharmacological and therapeutic potential of Ranolazine beyond antianginal drug use: a new insight. [PDF]
Singh D +2 more
europepmc +1 more source

