Results 211 to 220 of about 1,774 (249)

Risk of cardiovascular disease and mortality among women with endometriosis: Genetic insights

open access: yes
Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 3, Page 553-554, March 2026.
Maria I. Zervou   +3 more
wiley   +1 more source

Deregulated megakaryocytic maturation, mitochondrial function and inflammatory signalling in CYCS(c.292T>C)‐related thrombocytopenia

open access: yes
British Journal of Haematology, Volume 208, Issue 3, Page 1153-1157, March 2026.
Konstantina Giavi   +10 more
wiley   +1 more source

Computational Inference of Metabolic Programs: A Case Study Analyzing the Effect of BRCA1 Loss

open access: yes
Masid M   +12 more
europepmc   +1 more source
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Deregulated transcription factors in cancer cell metabolisms and reprogramming

Seminars in Cancer Biology, 2022
Metabolic reprogramming is an important cancer hallmark that plays a key role in cancer malignancies and therapy resistance. Cancer cells reprogram the metabolic pathways to generate not only energy and building blocks but also produce numerous key signaling metabolites to impact signaling and epigenetic/transcriptional regulation for cancer cell ...
Rajni, Kant   +7 more
openaire   +2 more sources

Deregulation of Collagen Metabolism in Human Stomach Cancer

Pathobiology, 2004
<i>Objective:</i> The defects of collagen metabolism are responsible for the disorganization of extracellular matrix in stomach cancer. Collagen through interaction with integrin receptors regulates the cellular growth, differentiation, gene expression, prolidase and gelatinase activity and plays an important role in tumorigenesis and ...
Tomasz, Guszczyn, Krzysztof, Sobolewski
openaire   +3 more sources

Deregulated Tyrosine–Phenylalanine Metabolism in Pulmonary Tuberculosis Patients

Journal of Proteome Research, 2015
Metabolic profiling of biofluids from tuberculosis (TB) patients would help us in understanding the disease pathophysiology and may also be useful for the development of novel diagnostics and host-directed therapy. In this pilot study we have compared the urine metabolic profiles of two groups of subjects having similar TB symptoms and categorized as ...
Mrinal Kumar, Das   +7 more
openaire   +2 more sources

Deregulated Sphingolipid Metabolism and Membrane Organization in Neurodegenerative Disorders

Molecular Neurobiology, 2010
Sphingolipids are polar membrane lipids present as minor components in eukaryotic cell membranes. Sphingolipids are highly enriched in nervous cells, where they exert important biological functions. They deeply affect the structural and geometrical properties and the lateral order of cellular membranes, modulate the function of several membrane ...
PICCININI, Marco   +12 more
openaire   +4 more sources

Purine metabolism gene deregulation in Parkinson's disease

Neuropathology and Applied Neurobiology, 2015
AimsTo explore alterations in the expression of genes encoding enzymes involved in purine metabolism in Parkinson's disease (PD) brains as purines are the core of the DNA, RNA, nucleosides and nucleotides which participate in a wide variety of crucial metabolic pathways.MethodsAnalysis of mRNA using real‐time quantitative PCR of 22 genes involved in ...
Paula, Garcia-Esparcia   +4 more
openaire   +2 more sources

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