Results 161 to 170 of about 1,151,626 (269)

The relationship between appetite hormones and body mass index in children with intoxication type metabolic diseases. [PDF]

Orphanet J Rare Dis
Koç N, Konyalıgil DB, Özen Yeşil B, Kaldırım B, Tel Adıgüzel K, Kıreker Köylü O, Kasapkara ÇS, Fırat Oğuz E, Eren F, Esgi M, Ünal Uzun Ö, Gündüz M.   +11 more
europepmc   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Nanomedicines Against Mitochondrial Dysfunction-Induced Metabolic Diseases. [PDF]

Adv Sci (Weinh)
Xu K, Wang L, Lv T, Jin C, Wu Q, Zhou Y, Xu G, Duan Z, Luo K, Yang J.   +9 more
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Editorial: Natural medicines for metabolic diseases - computational and pharmacological approaches, Volume II. [PDF]

Front Pharmacol
Stalin A, Sunil C, Hesham AE, Ignacimuthu S, Zou Q, Wang Y.   +5 more
europepmc   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Mitigation of Metabolic Diseases Through Personalized Nutrition: A Critical In-Depth Review. [PDF]

Food Sci Nutr
Arshad MT, Ali MKM, Awlqadr FH, Maqsood S, Ikram A, Hossain MS, Abdullahi MA, Rashed MM.   +7 more
europepmc   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Microbiota-Gut-Brain Axis Disruption, Neuroinflammation, and Potential Antioxidant-Based Treatments in Metabolic Diseases. [PDF]

Antioxidants (Basel)
Carro-Rodríguez J, Ibáñez-Cervantes G, Cárdenas-Rodríguez N, Ignacio-Mejía I, Albores-Méndez EM, Pardo-Pacheco BR, Fernández-Sánchez V, Balboa-Verduzco AM, Adame C, Lara-Padilla E, Mancilla-Ramírez J, Medina-Santillán R, Montoya-Olvera M, Cortes-Algara AL, Gómez-Manzo S, Hernández-Ochoa B, Moya-Amaya H, Bandala C.   +17 more
europepmc   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source