Results 11 to 20 of about 898,161 (347)

Integrated Solid-Phase Extraction, Ultra-High-Performance Liquid Chromatography–Quadrupole-Orbitrap High-Resolution Mass Spectrometry, and Multidimensional Data-Mining Techniques to Unravel the Metabolic Network of Dehydrocostus Lactone in Rats

Molecules, 2022
Dehydrocostus lactone (DL) is among the representative ingredients of traditional Chinese medicine (TCM), with excellent anticancer, antibacterial, and anti-inflammatory activities.
Yingying Tian, Beibei Ma, Chuang Liu, Xinyue Zhao, Shangyue Yu, Yilin Li, Shiqiu Tian, Hailuan Pei, Zijian Wang, Zeping Zuo, Zhibin Wang   +10 more
doaj   +1 more source

Attractor Metabolic Networks

PLoS ONE, 2013
The experimental observations and numerical studies with dissipative metabolic networks have shown that cellular enzymatic activity self-organizes spontaneously leading to the emergence of a Systemic Metabolic Structure in the cell, characterized by a set of different enzymatic reactions always locked into active states (metabolic core) while the rest ...
Fuente, Ildefonso M. de la, Cortés, Jesús M., Pelta Mochcovsky, David Alejandro, Veguillas, Juan   +3 more
openaire   +6 more sources

Hybrid Metabolic Network Completion [PDF]

Theory and Practice of Logic Programming, 2017
AbstractMetabolic networks play a crucial role in biology since they capture all chemical reactions in an organism. While there are networks of high quality for many model organisms, networks for less studied organisms are often of poor quality and suffer from incompleteness.
Frioux, Clémence, Schaub, Torsten, Schellhorn, Sebastian, Siegel, Anne, Wanko, Philipp   +4 more
openaire   +4 more sources

Metabolic syndrome in healthcare personnel at the University of Antioquia-Colombia: LATINMETS study

Nutrición Hospitalaria, 2013
Introduction: Hypertension (HTN), atherogenic dyslipidemia, an increased glycemia in a fasting state, and abdominal obesity (AO), constitute a cluster of risk factors for cardiovascular disease named metabolic syndrome (MS).
Laura I. González-Zapata, Gloria Cecilia Deossa, Julia Monsalve-Álvarez, Juliana Díaz-García, Nancy Babio, Jordi Salas-Salvado   +5 more
doaj   +1 more source

MultiMetEval: comparative and multi-objective analysis of genome-scale metabolic models [PDF]

, 2012
Comparative metabolic modelling is emerging as a novel field, supported by the development of reliable and standardized approaches for constructing genome-scale metabolic models in high throughput.
A Freitag, A Gevorgyan, A Mithani, Albert Gevorgyan, AM Feist, AM Feist, AM Feist, Andrzej M. Kierzek, AP Burgard, BA Pfeifer, CS Henry, D Nagrath, DC Alexander, DC Stevens, EM Paradise, Eriko Takano, FC Lee, H Ikeda, I Thiele, J Gonzalez-Lergier, J Romero, J Schellenberger, JD Orth, JL Adrio, JP Brooks, JS Edwards, K Nieselt, K Yanai, LM Blank, M DeJongh, M Durot, M Kanehisa, M Latendresse, MA Fischbach, MA Oberhardt, MA Oberhardt, MA Oberhardt, Marnix H. Medema, MH Medema, MH Medema, MH Medema, MH Medema, MT Alam, MT Alam, MW Covert, N Scherr, ND Price, ND Price, NE Lewis, Piotr Zakrzewski, PR Ives, R Breitling, R Schuetz, Rainer Breitling, SA Becker, SD Bentley, Stephen S. Fong, TD Vo, TY Kim, XQ Zhao   +59 more
core   +6 more sources

Transcriptome Analysis Reveals the Flexibility of Cordycepin Network in Cordyceps militaris Activated by L-Alanine Addition

Frontiers in Microbiology, 2020
Cordycepin, isolated from the traditional medicinal fungus Cordyceps militaris, has gained much attention due to its various clinical functions. Previous reports of L-alanine addition could significantly improve cordycepin production, but the molecular ...
Bai-Xiong Chen, Bai-Xiong Chen, Tao Wei, Tao Wei, Ling-Na Xue, Ling-Na Xue, Qian-Wang Zheng, Qian-Wang Zheng, Zhi-Wei Ye, Zhi-Wei Ye, Yuan Zou, Yuan Zou, Yi Yang, Yi Yang, Fan Yun, Li-Qiong Guo, Li-Qiong Guo, Jun-Fang Lin, Jun-Fang Lin   +18 more
doaj   +1 more source

Consumption of low doses of fat prevents the postprandial rise in chylomicron particle concentration and remnant accumulation in healthy normolipidaemic males

Journal of Nutritional Science, 2012
Chylomicron particles are continually synthesised and secreted from the intestine even in the absence of ingested fat. It is possible that following consumption of low doses of fat the basal level of chylomicron secretion and subsequent metabolism are ...
Anthony P. James, John C. Mamo
doaj   +1 more source

MetExploreViz: web component for interactive metabolic network visualization [PDF]

, 2017
Summary: MetExploreViz is an open source web component that can be easily embedded in any web site. It provides features dedicated to the visualization of metabolic networks and pathways and thus offers a flexible solution to analyse omics data in a ...
Chazalviel, Maxime, Cottret, Ludovic, Frainay, Clément, Gloaguen, Yoann, Jourdan, Fabien, Merlet, Benjamin, Poupin, Nathalie, Vinson, Florence   +7 more
core   +4 more sources

Flux networks in metabolic graphs [PDF]

, 2009
A metabolic model can be represented as bipartite graph comprising linked reaction and metabolite nodes. Here it is shown how a network of conserved fluxes can be assigned to the edges of such a graph by combining the reaction fluxes with a conserved ...
Dantzig G B, J L Jones, Jerrold J H, P B Warren, Palsson B Ø, Press W H, Reed J L, S M Duarte Queiros, Smith E B, Temkin O N   +9 more
core   +1 more source

Estimating the size of the solution space of metabolic networks [PDF]

, 2007
In this work we propose a novel algorithmic strategy that allows for an efficient characterization of the whole set of stable fluxes compatible with the metabolic constraints.
Braunstein, Alfredo, Mulet, Roberto, Pagnani, Andrea   +2 more
core   +4 more sources