Results 11 to 20 of about 911,565 (297)

Integrated Solid-Phase Extraction, Ultra-High-Performance Liquid Chromatography–Quadrupole-Orbitrap High-Resolution Mass Spectrometry, and Multidimensional Data-Mining Techniques to Unravel the Metabolic Network of Dehydrocostus Lactone in Rats

open access: yesMolecules, 2022
Dehydrocostus lactone (DL) is among the representative ingredients of traditional Chinese medicine (TCM), with excellent anticancer, antibacterial, and anti-inflammatory activities.
Yingying Tian   +10 more
doaj   +1 more source

Attractor Metabolic Networks

open access: yesPLoS ONE, 2013
The experimental observations and numerical studies with dissipative metabolic networks have shown that cellular enzymatic activity self-organizes spontaneously leading to the emergence of a Systemic Metabolic Structure in the cell, characterized by a set of different enzymatic reactions always locked into active states (metabolic core) while the rest ...
Fuente, Ildefonso M. de la   +3 more
openaire   +6 more sources

Why Optimal States Recruit Fewer Reactions in Metabolic Networks [PDF]

open access: yes, 2012
The metabolic network of a living cell involves several hundreds or thousands of interconnected biochemical reactions. Previous research has shown that under realistic conditions only a fraction of these reactions is concurrently active in any given cell.
Lee, Joo Sang   +2 more
core   +1 more source

Hybrid Metabolic Network Completion [PDF]

open access: yesTheory and Practice of Logic Programming, 2017
AbstractMetabolic networks play a crucial role in biology since they capture all chemical reactions in an organism. While there are networks of high quality for many model organisms, networks for less studied organisms are often of poor quality and suffer from incompleteness.
Frioux, Clémence   +4 more
openaire   +4 more sources

Metabolic syndrome in healthcare personnel at the University of Antioquia-Colombia: LATINMETS study

open access: yesNutrición Hospitalaria, 2013
Introduction: Hypertension (HTN), atherogenic dyslipidemia, an increased glycemia in a fasting state, and abdominal obesity (AO), constitute a cluster of risk factors for cardiovascular disease named metabolic syndrome (MS).
Laura I. González-Zapata   +5 more
doaj   +1 more source

Network motif frequency vectors reveal evolving metabolic network organisation [PDF]

open access: yes, 2014
At the systems level many organisms of interest may be described by their patterns of interaction, and as such, are perhaps best characterised via network or graph models.
Chuzhanova, N, Crofts, JJ, Pearcy, N
core   +1 more source

Transcriptome Analysis Reveals the Flexibility of Cordycepin Network in Cordyceps militaris Activated by L-Alanine Addition

open access: yesFrontiers in Microbiology, 2020
Cordycepin, isolated from the traditional medicinal fungus Cordyceps militaris, has gained much attention due to its various clinical functions. Previous reports of L-alanine addition could significantly improve cordycepin production, but the molecular ...
Bai-Xiong Chen   +18 more
doaj   +1 more source

Integrated Regulatory and Metabolic Networks of the Marine Diatom Phaeodactylum tricornutum Predict the Response to Rising CO2 Levels. [PDF]

open access: yes, 2017
Diatoms are eukaryotic microalgae that are responsible for up to 40% of the ocean's primary productivity. How diatoms respond to environmental perturbations such as elevated carbon concentrations in the atmosphere is currently poorly understood.
Andrew E. Allen   +5 more
core   +3 more sources

Exploring the metabolic network of the epidemic pathogen Burkholderia cenocepacia J2315 via genome-scale reconstruction [PDF]

open access: yes, 2011
BACKGROUND: Burkholderia cenocepacia is a threatening nosocomial epidemic pathogen in patients with cystic fibrosis (CF) or a compromised immune system. Its high level of antibiotic resistance is an increasing concern in treatments against its infection.
Fang, K.   +9 more
core   +2 more sources

Consumption of low doses of fat prevents the postprandial rise in chylomicron particle concentration and remnant accumulation in healthy normolipidaemic males

open access: yesJournal of Nutritional Science, 2012
Chylomicron particles are continually synthesised and secreted from the intestine even in the absence of ingested fat. It is possible that following consumption of low doses of fat the basal level of chylomicron secretion and subsequent metabolism are ...
Anthony P. James, John C. Mamo
doaj   +1 more source

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