Results 31 to 40 of about 898,161 (347)

Metabolic network modularity arising from simple growth processes

, 2012
Metabolic networks consist of linked functional components, or modules. The mechanism underlying metabolic network modularity is of great interest not only to researchers of basic science but also to those in fields of engineering.
Takemoto, Kazuhiro
core   +1 more source

Branching process approach for Boolean bipartite networks of metabolic reactions

, 2012
The branching process (BP) approach has been successful in explaining the avalanche dynamics in complex networks. However, its applications are mainly focused on unipartite networks, in which all nodes are of the same type.
B. Kahng, Deokjae Lee, K.-I. Goh, T. E. Harris   +3 more
core   +1 more source

Genome-Scale Metabolic Reconstruction and in Silico Perturbation Analysis of the Polar Diatom Fragilariopsis cylindrus Predicts High Metabolic Robustness

Biology, 2020
Diatoms are major primary producers in polar environments where they can actively grow under extremely variable conditions. Integrative modeling using a genome-scale model (GSM) is a powerful approach to decipher the complex interactions between ...
Michel Lavoie, Blanche Saint-Béat, Jan Strauss, Sébastien Guérin, Antoine Allard, Simon V. Hardy, Angela Falciatore, Johann Lavaud   +7 more
doaj   +1 more source

Stage-dependent differential influence of metabolic and structural networks on memory across Alzheimer’s disease continuum

eLife, 2022
Background: Large-scale neuronal network breakdown underlies memory impairment in Alzheimer’s disease (AD). However, the differential trajectories of the relationships between network organisation and memory across pathology and cognitive stages in AD ...
Kok Pin Ng, Xing Qian, Kwun Kei Ng, Fang Ji, Pedro Rosa-Neto, Serge Gauthier, Nagaendran Kandiah, Juan Helen Zhou, Alzheimer's Disease Neuroimaging Initiative   +8 more
doaj   +1 more source

Remnants of an ancient metabolism without phosphate [PDF]

, 2017
Phosphate is essential for all living systems, serving as a building block of genetic and metabolic machinery. However, it is unclear how phosphate could have assumed these central roles on primordial Earth, given its poor geochemical accessibility.
Goldford, Joshua E., Hartman, Hyman, Segrè, Daniel, Smith, Temple F.   +3 more
core   +1 more source

Heterosis Is a Systemic Property Emerging From Non-linear Genotype-Phenotype Relationships: Evidence From in Vitro Genetics and Computer Simulations

Frontiers in Genetics, 2018
Heterosis, the superiority of hybrids over their parents for quantitative traits, represents a crucial issue in plant and animal breeding as well as evolutionary biology.
Julie B. Fiévet, Thibault Nidelet, Christine Dillmann, Dominique de Vienne   +3 more
doaj   +1 more source

Reconstruction and analyses of genome-scale halomonas metabolic network yield a highly efficient PHA production. [PDF]

Metab Eng Commun
Zhang L, Sun X, Ye J, Yuan Q, Zhang X, Sun F, An Y, Chen Y, Qian Y, Yang D, Wang Q, Gao M, Chen T, Ma H, Chen G, Xie Z.   +15 more
europepmc   +2 more sources

Network motif frequency vectors reveal evolving metabolic network organisation [PDF]

, 2014
At the systems level many organisms of interest may be described by their patterns of interaction, and as such, are perhaps best characterised via network or graph models.
Chuzhanova, N, Crofts, JJ, Pearcy, N
core   +1 more source

A Metabolic Network Mediating the Cycling of Succinate, a Product of ROS Detoxification into α-Ketoglutarate, an Antioxidant

Antioxidants, 2022
Sulfur is an essential element for life. However, the soil microbe Pseudomonas (P.) fluorescens can survive in a low sulfur environment. When cultured in a sulfur-deficient medium, the bacterium reprograms its metabolic pathways to produce α ...
Félix Legendre, Alex MacLean, Sujeenthar Tharmalingam, Vasu D. Appanna   +3 more
doaj   +1 more source

Integrated Regulatory and Metabolic Networks of the Marine Diatom Phaeodactylum tricornutum Predict the Response to Rising CO2 Levels. [PDF]

, 2017
Diatoms are eukaryotic microalgae that are responsible for up to 40% of the ocean's primary productivity. How diatoms respond to environmental perturbations such as elevated carbon concentrations in the atmosphere is currently poorly understood.
Andrew E. Allen, Bernhard O. Palsson, Christopher L. Dupont, Jennifer Levering, Karsten Zengler, Xiaoxia Lin   +5 more
core   +3 more sources