Results 131 to 140 of about 282,038 (168)
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Microbial regulatory and metabolic networks
Current Opinion in Biotechnology, 2007Reconstruction of transcriptional regulatory and metabolic networks is the foundation of large-scale microbial systems and synthetic biology. An enormous amount of information including the annotated genomic sequences and the genomic locations of DNA-binding regulatory proteins can be used to define metabolic and regulatory networks in cells.
Cho, BK Cho, Byung-Kwan +3 more
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VRML metabolic network visualizer
Computers in Biology and Medicine, 2003A successful date collection visualization should satisfy a set of many requirements: unification of diverse data formats, support for serendipity research, support of hierarchical structures, algorithmizability, vast information density, Internet-readiness, and other.
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Flux modules in metabolic networks
Journal of Mathematical Biology, 2013The huge number of elementary flux modes in genome-scale metabolic networks makes analysis based on elementary flux modes intrinsically difficult. However, it has been shown that the elementary flux modes with optimal yield often contain highly redundant information. The set of optimal-yield elementary flux modes can be compressed using modules.
Müller, Arne C., Bockmayr, Alexander
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Network Analysis of Metabolic Networks
2013Στη παρούσα διπλωματική εργασία επιχειρούμε μια εξονυχιστική εξέταση των μεταβολικών δικτύων και εξετάζουμε τη στατιστική τους συμπεριφορά. Κύριο εργαλείο σε αυτή μας την έρευνα είναι η θεωρία δικτύων. Έτσι, ξεκινάμε με μια όσο το δυνατό πιο πλήρη αναφορά στην παραπάνω θεωρία και τις ιδιότητες που την διακατέχουν. Έννοιες όπως μικρόκοσμος, κατανομή των
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A source of stability in metabolic networks
Journal of Theoretical Biology, 1972Abstract The generally observed monotonic dependence of enzyme activity on substrate concentration is utilized to give a plausible account of some aspects of the behavior of complex biochemical networks on the “metabolic” time scale. The adduced dynamical equations are shown to prescribe a “canalized” metabolic behavior, in which flow lines in state ...
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Genome-Scale Metabolic Networks
2019This chapter discusses the benefits of interpreting metabolomics data in the context of genome-scale metabolic networks. These networks gather all the metabolic reactions occuring in an organism, a tissue or a cell, thus providing a biological background to decipher the role of metabolites of interest.
Frainay, Clément, Jourdan, Fabien
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Qualitative Modelling of Metabolic Networks
2013Abstract Global and untargeted approaches such as metabolomics require analysis of experimental data with no assumption regarding the organism’s functions affected by any environmental or genetic stress. From a metabolism perspective, it means that the metabolic shift induced by the studied perturbation may span several pathways.
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Systematic Identification of MACC1-Driven Metabolic Networks in Colorectal Cancer
Cancers, 2021Ulrike Stein +2 more
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Evolution of biomolecular networks — lessons from metabolic and protein interactions
Nature Reviews Molecular Cell Biology, 2009Peer Börk, Takuji Yamada, Börk Peer
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