Results 261 to 270 of about 297,984 (312)

Understanding and computational design of genetic circuits of metabolic networks. [PDF]

Essays Biochem
Berkvens A, Salinas L, Remeijer M, Planqué R, Teusink B, Bruggeman FJ.   +5 more
europepmc   +1 more source

<i>Meta</i>Biome: a multiscale model integrating agent-based and metabolic networks to reveal spatial regulation in gut mucosal microbial communities. [PDF]

mSystems
Aminian-Dehkordi J, Dickson A, Valiei A, Mofrad MRK.   +3 more
europepmc   +1 more source

QSAR-Based Drug Repurposing and RNA-Seq Metabolic Networks Highlight Treatment Opportunities for Hepatocellular Carcinoma Through Pyrimidine Starvation. [PDF]

Cancers (Basel)
Talubo NDD, Dela Cruz EWB, Fowler PMPT, Tsai PW, Tayo LL.   +4 more
europepmc   +1 more source

fluxTrAM: Integration of tracer-based metabolomics data into atomically resolved genome-scale metabolic networks for metabolic flux analysis

Huang L, Preciat G, Alarcon-Gil J, Moreno EL, Wegrzyn A, Thiele I, Schymanski EL, Harms A, Fleming RM, Hankemeier T.   +9 more
europepmc   +1 more source

Microbial regulatory and metabolic networks [PDF]

Current Opinion in Biotechnology, 2007
Reconstruction of transcriptional regulatory and metabolic networks is the foundation of large-scale microbial systems and synthetic biology. An enormous amount of information including the annotated genomic sequences and the genomic locations of DNA-binding regulatory proteins can be used to define metabolic and regulatory networks in cells.
Cho, BK Cho, Byung-Kwan, Charusanti, P Charusanti, Pep, Herrgard, MJ Herrgard, Markus J., Palsson, BO Palsson, Bernhard O.   +3 more
openaire   +4 more sources

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Deciphering metabolic networks

European Journal of Biochemistry, 2003
All higher organisms divide major biochemical steps into different cellular compartments and often use tissue‐specific division of metabolism for the same purpose. Such spatial resolution is accompanied with temporal changes of metabolite synthesis in response to environmental stimuli or developmental needs.
Fiehn, O., Weckwerth, W.
openaire   +3 more sources

Metabolic Network of Nucleosides in the Brain

Current Topics in Medicinal Chemistry, 2011
Brain relies on circulating nucleosides, mainly synthesised de novo in the liver, for the synthesis of nucleotides, RNA, nuclear and mitochondrial DNA, coenzymes, and pyrimidine sugar- and lipid-conjugates. Essentially, the paths of nucleoside salvage in the brain include a two step conversion of inosine and guanosine to IMP and GMP, respectively, and ...
Ipata PL, CAMICI, MARCELLA, Micheli V, TOZZI, MARIA GRAZIA   +3 more
openaire   +3 more sources

Modelling Metabolic Networks—The Theories of Metabolism

2013
Abstract There are several theoretical approaches to metabolism. Some of them give a greater place to the structure of the metabolic network symbolized by its stoichiometry matrix. The constraints in a metabolic network are very strong so that a lot of information can be derived from the stoichiometry matrix without any knowledge of the kinetic ...
Mazat, Jean-Pierre, Beauvoit, Bertrand
openaire   +2 more sources

Metabolic Networks

2009
World Scientific Lecture Notes in Complex ...
Maria Concetta Palumbo, Lorenzo Farina, Alfredo Colosimo, Alessandro Giuliani   +3 more
openaire   +3 more sources

Metabolic Networking

Science, 2012
A key design principle of bacterial metabolic networks is optimal performance, but not at the expense of adaptability.
openaire   +2 more sources