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Genome-Scale Metabolic Networks
2019This chapter discusses the benefits of interpreting metabolomics data in the context of genome-scale metabolic networks. These networks gather all the metabolic reactions occuring in an organism, a tissue or a cell, thus providing a biological background to decipher the role of metabolites of interest.
Frainay, Clément, Jourdan, Fabien
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Qualitative Modelling of Metabolic Networks
2013Abstract Global and untargeted approaches such as metabolomics require analysis of experimental data with no assumption regarding the organism’s functions affected by any environmental or genetic stress. From a metabolism perspective, it means that the metabolic shift induced by the studied perturbation may span several pathways.
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Evolution of biomolecular networks — lessons from metabolic and protein interactions
Nature Reviews Molecular Cell Biology, 2009Takuji Yamada +2 more
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Critical assessment of genome-scale metabolic networks: the need for a unified standard
Briefings in Bioinformatics, 2015Aarthi Ravikrishnan +2 more
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