Results 61 to 70 of about 335,580 (367)
Understanding the evolution of functional redundancy in metabolic networks
Bioinform., 2018 Motivation Metabolic networks have evolved to reduce the disruption of key metabolic pathways by the establishment of redundant genes/reactions. Synthetic lethals in metabolic networks provide a window to study these functional redundancies.
Gayathri Sambamoorthy, Karthik Raman
semanticscholar +1 more source
MetExploreViz: web component for interactive metabolic network visualization [PDF]
, 2017 Summary: MetExploreViz is an open source web component that can be easily embedded in any web site. It provides features dedicated to the visualization of metabolic networks and pathways and thus offers a flexible solution to analyse omics data in a ...
Chazalviel, Maxime +7 more
core +3 more sources
The Streptomyces coelicolor small ORF trpM stimulates growth and morphological development and exerts opposite effects on actinorhodin and calcium-dependent antibiotic production [PDF]
, 2020 In actinomycetes, antibiotic production is often associated with a morpho-physiological differentiation program that is regulated by complex molecular and metabolic networks. Many aspects of these regulatory circuits have been already elucidated and many
Alberto Vassallo +7 more
core +2 more sources
VitisCyc: A metabolic pathway knowledgebase for grapevine (Vitis vinifera)
Frontiers in Plant Science, 2014 We have developed VitisCyc, a grapevine-specific metabolic pathway database that allows researchers to i) search and browse the database for its various components such as metabolic pathways, reactions, compounds, genes and proteins, ii) compare ...
Sushma eNaithani +6 more
doaj +1 more source
Journal of Veterinary Medical Science, 2019 High-producing dairy cows are easily affected by left displacement of the abomasum (LDA) within 4 weeks postpartum. Although LDA is highly associated with metabolic disturbances, the related information on comprehensive metabolic changes, with the ...
Y. Guo, J. Tao, Li Hua Xu, F. Wei, S. He
semanticscholar +1 more source
Pathway identification by network pruning in the metabolic network of Escherichia coli [PDF]
Bioinformatics, 2009 Abstract Motivation: All metabolic networks contain metabolites, such as ATP and NAD, known as currency metabolites, which take part in many reactions. These are often removed in the study of these networks, but no consensus exists on what actually constitutes a currency metabolite, and it is also unclear how these highly connected nodes
Gerlee, Philip David Marcus +2 more
openaire +3 more sources
MetaboCraft: building a Minecraft plugin for metabolomics [PDF]
, 2018 Motivation: The rapid advances in metabolomics pose a significant challenge in presentation and interpretation of results. Development of new, engaging visual aids is crucial to advancing our understanding of new findings. Results: We have developed
Burgess, Karl +2 more
core +1 more source
Reconciled rat and human metabolic networks for comparative toxicogenomics and biomarker predictions
Nature Communications, 2017 The laboratory rat has been used as a surrogate to study human biology for more than a century. Here we present the first genome-scale network reconstruction of Rattus norvegicus metabolism, iRno, and a significantly improved reconstruction of human ...
E. Blais +7 more
semanticscholar +1 more source
Phylophenetic properties of metabolic pathway topologies as revealed by global analysis
BMC Bioinformatics, 2006 Background As phenotypic features derived from heritable characters, the topologies of metabolic pathways contain both phylogenetic and phenetic components.
Sun Shiwei +9 more
doaj +1 more source
BMC Urology, 2019 Background Human sperm cryopreservation is a simple and effective approach for male fertility preservation. Methods To identify potential proteomic changes in this process, data-independent acquisition (DIA), a technology with high quantitative accuracy ...
Longlong Fu +11 more
doaj +1 more source