Results 71 to 80 of about 374,876 (335)
Law of localization in chemical reaction networks
, 2016 In living cells, chemical reactions are connected by sharing their products and substrates, and form complex networks, e.g. metabolic pathways. Here we developed a theory to predict the sensitivity, i.e.
Mochizuki, Atsushi, Okada, Takashi
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Synthetic biology—putting engineering into biology [PDF]
, 2006 Synthetic biology is interpreted as the engineering-driven building of increasingly complex biological entities for novel applications. Encouraged by progress in the design of artificial gene networks, de novo DNA synthesis and protein engineering, we ...
Heinemann, Matthias,, Panke, Sven,
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Modular decomposition of metabolic reaction networks based on flux analysis and pathway projection [PDF]
Bioinformatics, 2007 AbstractMotivation: The rational decomposition of biochemical networks into sub-structures has emerged as a useful approach to study the design of these complex systems. A biochemical network is characterized by an inhomogeneous connectivity distribution, which gives rise to several organizational features, including modularity.
Jeongah, Yoon +3 more
openaire +2 more sources
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Multinuclear NMR spectroscopy and isotopomer distribution analysis applied to metabolic phenotype characterization of complex systems [PDF]
, 2014 In the present work, the complex metabolic effects of a rag8 genetic mutation performed on Kluyveromyces lactis yeast cells is investigated with a specific, ‘information-rich’ analytical approach: differential NMR metabolomics. The use of such NMR-based
GORIETTI, DANIELA
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Edge vulnerability in neural and metabolic networks
, 2004 Biological networks, such as cellular metabolic pathways or networks of corticocortical connections in the brain, are intricately organized, yet remarkably robust toward structural damage.
Hilgetag, Claus C., Kaiser, Marcus
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Different adaptation strategies of two citrus scion/rootstock combinations in response to drought stress [PDF]
, 2017 Scion/rootstock interaction is important for plant development and for breeding programs. In this context, polyploid rootstocks presented several advantages, mainly in relation to biotic and abiotic stresses.
Bonatto, Diego +6 more
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Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Analysis on relationship between extreme pathways and correlated reaction sets
BMC Bioinformatics, 2009 Background Constraint-based modeling of reconstructed genome-scale metabolic networks has been successfully applied on several microorganisms. In constraint-based modeling, in order to characterize all allowable phenotypes, network-based pathways, such ...
Wang Weirong +4 more
doaj +1 more source
Design and Development of Software Tools for Bio-PEPA [PDF]
, 2009 This paper surveys the design of software tools for the Bio-PEPA process algebra. Bio-PEPA is a high-level language for modelling biological systems such as metabolic pathways and other biochemical reaction networks.
Duguid, Adam +4 more
core +3 more sources