Results 71 to 80 of about 335,580 (367)
Exploring metabolic pathway disruption in the subchronic phencyclidine model of schizophrenia with the generalized singular value decomposition [PDF]
, 2011 The quantification of experimentally-induced alterations in biological pathways remains a major challenge in systems biology. One example of this is the quantitative characterization of alterations in defined, established metabolic pathways from complex ...
Dawson, Neil +6 more
core +4 more sources
Reconstruction of Tissue-Specific Metabolic Networks Using CORDA
PLoS Comput. Biol., 2016 Human metabolism involves thousands of reactions and metabolites. To interpret this complexity, computational modeling becomes an essential experimental tool.
A. Schultz, A. Qutub
semanticscholar +1 more source
On functional module detection in metabolic networks [PDF]
, 2013 Functional modules of metabolic networks are essential for understanding the metabolism of an organism as a whole. With the vast amount of experimental data and the construction of complex and large-scale, often genome-wide, models, the computer-aided ...
Adleman +29 more
core +2 more sources
Predicting networking couples for metabolic pathways of Arabidopsis [PDF]
, 2006 EXCLI Journal ; Vol.
Cai, Yu-Dong +2 more
openaire +2 more sources
Biochemistry, 2019 The assignment of functions to uncharacterized proteins discovered in genome projects requires easily accessible tools and computational resources for large-scale, user-friendly leveraging of the protein, genome, and metagenome databases by ...
Rémi Zallot, Nils Oberg, J. Gerlt
semanticscholar +1 more source
Scientific Reports, 2017 Powdered activated carbon (AC) is commonly used as an effective additive to enhance anaerobic digestion (AD), but little is known about how the metabolic pathways resulting from adding AC change the microbial association network and enhance food waste ...
Jingxin Zhang +5 more
semanticscholar +1 more source
Good Learning and Implicit Model Enumeration [PDF]
, 2005 MathSBML is an open-source, freely-downloadable Mathematica package that facilitates working with Systems Biology Markup Language (SBML) models. SBML is a toolneutral,computer-readable format for representing models of biochemical reaction networks ...
A. Finney +12 more
core +5 more sources
Discriminating response groups in metabolic and regulatory pathway networks [PDF]
Bioinformatics, 2012 Abstract Motivation: Analysis of omics experiments generates lists of entities (genes, metabolites, etc.) selected based on specific behavior, such as changes in response to stress or other signals. Functional interpretation of these lists often uses category enrichment tests using functional annotations like Gene Ontology terms and ...
John L. Van Hemert, Julie A. Dickerson
openaire +3 more sources
The global integrative network: integration of signaling and metabolic pathways
aBIOTECH, 2022 Abstract The crosstalk between signaling and metabolic pathways has been known to play key roles in human diseases and plant biological processes. The integration of signaling and metabolic pathways can provide an essential reference framework for crosstalk analysis.
Yuying Lin +4 more
openaire +2 more sources
Cancer metabolism: a modeling perspective
Frontiers in Physiology, 2015 Tumor cells alter their metabolism to maintain unregulated cellular proliferation and survival, but this transformation leaves them reliant on constant supply of nutrients and energy.
Pouyan eGhaffari Nouran +5 more
doaj +1 more source