Results 91 to 100 of about 972,456 (315)
MoleculesCancer remains a significant global public health concern. Numerous challenges still remain in its treatment. Recently, a novel two-dimensional material—violet phosphorene nanosheets (VPNS)—has shown considerable application potential in the biomedical ...
Xinyi Zhao +7 more
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Structure and flux analysis of metabolic networks
, 2009 Conceptual understanding of complex cellular organization can be facilitated through a perspective based on the central dogma of biology1 (Figure 17.1). Accordingly, information coded in a genome is translated into proteins via mRNA.
Patil, K. R., +2 more
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Comparative Genome Analysis of Piscine Vibrio vulnificus: Virulence-Associated Metabolic Pathways
MicroorganismsVibriosis caused by Vibrio vulnificus is a major problem in aquatic animals, particularly brown marble groupers (Epinephelus fuscoguttatus). V. vulnificus biotype I has recently been isolated and classified into subgroups SUKU_G1, SUKU_G2, and SUKU_G3 ...
Thararat Phurahong +6 more
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Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Characteristic metabolite profile of 10 colorectal cancer-related bacteria
Frontiers in OncologyBackgroundTumor metabolomics of colorectal cancer (CRC) is significantly different from normal tissues, due to nutrient deprivation, metabolite accumulation, acidity and hypoxia. Besides, gut microbiota has been confirmed to affect the progression of CRC.
Yongqiang Liu +6 more
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Metabolic Pathway of Cardiac Troponins and Its Diagnostic Value
Vascular Health and Risk Management, 2022 Aleksey Chaulin1,2 1Department of Cardiology and Cardiovascular Surgery, Samara State Medical University, Samara, 443099, Russia; 2Department of Histology and Embryology, Samara State Medical University, Samara, 443099, RussiaCorrespondence: Aleksey ...
Chaulin A
doaj
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Animal NutriomicsLycium barbarum by-products (LBPs), including residual branches, leaves and fruits generated during processing, are rich in bioactive compounds exhibiting antioxidant, anti-inflammatory and immunomodulatory properties.
Jie Liu +5 more
doaj +1 more source
Sensitivity analysis and experimental design of a stiff signal transduction pathway model
, 2007 Sensitivity analysis is normally used to analyze how sensitive a system is with respect to the change of parameters or initial conditions and is perhaps best known in systems biology via the formalism of metabolic control analysis [1, 2].
Yue, H. +4 more
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