Results 141 to 150 of about 1,386,772 (353)

Widely Targeted Metabolomics Analysis Revealed the Component Differences of Hemerocallis citrina Borani in Different Production Areas of Datong

open access: yesFoods
Hemerocallis citrina Borani (H. citrina) has garnered significant attention due to its abundant nutritional quality. Datong, located in Shanxi Province, is recognized as one of the four major production regions for high-quality H. citrina.
Yongxia Fu   +6 more
doaj   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

The Application of Metabolomics in Hyperlipidemia: Insights into Biomarker Discovery and Treatment Efficacy Assessment

open access: yesMetabolites
Hyperlipidemia is a lipid metabolism disorder that refers to increased levels of total triglycerides (TGs), cholesterol (TC), and low-density lipoprotein-cholesterol (LDL-C) and decreased levels of high-density lipoprotein-cholesterol (HDL-C).
Mohammad Alwahsh   +4 more
doaj   +1 more source

METABOLIC PATHWAYS OF HOMOSERINE IN THE MAMMAL

open access: hybrid, 1956
Y. Matsuo   +2 more
openalex   +1 more source

A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla   +15 more
wiley   +1 more source

Metabolic Engineering for the Biosynthesis of Pentalenene in the Rapidly Growing Bacterium Vibrio natriegens

open access: yesFermentation
Vibrio natriegens (V. natriegens) is an emerging synthetic biology chassis characterized by rapid growth, and its potential for the synthesis of sesquiterpenes (such as pentalenene) has not been developed.
Lujun Hu   +10 more
doaj   +1 more source

METABOLIC PATHWAYS OF GLYCEROL DISSIMILATION A

open access: bronze, 1953
Boris Magasanik   +2 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Metabolomic analysis of Grifola frondosa mycelium in different culture periods

open access: yesGuangxi Zhiwu
To gain a comprehensive understanding of the metabolite differences and metabolic pathways involved in the mycelium of Grifola frondosa during various culture periods, this study employed HPLC-MS/MS analysis to thoroughly investigate the mycelium ...
LIU Jinrong1,2, ZHANG Yancheng2, LIU Yan2, ZHANG Qiang3, LV Huqiang3,4, MOU Guangfu2*
doaj   +1 more source

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