Results 51 to 60 of about 1,386,772 (353)
Genomic reconstruction of short-chain fatty acid production by the human gut microbiota
Frontiers in Molecular Biosciences, 2022 Short-chain fatty acids (SCFAs) including acetate, formate, propionate, and butyrate are the end products of dietary fiber and host glycan fermentation by the human gut microbiota (HGM).
Maria S. Frolova +4 more
doaj +1 more source
Augmenting Biogas Process Modeling by Resolving Intracellular Metabolic Activity [PDF]
, 2019 The process of anaerobic digestion in which waste biomass is transformed to methane by complex microbial communities has been modeled for more than 16 years by parametric gray box approaches that simplify process biology and do not resolve intracellular ...
Denny Popp +7 more
core +1 more source
The large-scale organization of metabolic networks [PDF]
, 2000 In a cell or microorganism the processes that generate mass, energy, information transfer, and cell fate specification are seamlessly integrated through a complex network of various cellular constituents and reactions. However, despite the key role these
Albert, R. +4 more
core +3 more sources
Review of Machine Learning Methods for the Prediction and Reconstruction of Metabolic Pathways
Frontiers in Molecular Biosciences, 2021 Prediction and reconstruction of metabolic pathways play significant roles in many fields such as genetic engineering, metabolic engineering, drug discovery, and are becoming the most active research topics in synthetic biology.
Hayat Ali Shah +3 more
doaj +1 more source
Fructose metabolism in Chromohalobacter salexigens: interplay between the Embden–Meyerhof–Parnas and Entner–Doudoroff pathways [PDF]
, 2019 Background The halophilic bacterium Chromohalobacter salexigens metabolizes glucose exclusively through the Entner–Doudoroff (ED) pathway, an adaptation which results in inefficient growth, with significant carbon overflow, especially at low salinity ...
Argandoña Bertrán, Montserrat +12 more
core +1 more source
Circulating histones as clinical biomarkers in critically ill conditions
FEBS Letters, EarlyView.Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez +17 more
wiley +1 more source
The protein cost of metabolic fluxes: prediction from enzymatic rate laws and cost minimization
, 2016 Bacterial growth depends crucially on metabolic fluxes, which are limited by the cell's capacity to maintain metabolic enzymes. The necessary enzyme amount per unit flux is a major determinant of metabolic strategies both in evolution and bioengineering.
Bar-Even, Arren +5 more
core +6 more sources
Frontiers in Molecular Biosciences, 2021 Lumbar disc herniation (LDH) possesses complex pathogenesis, which has not been well elucidated yet. To date, specific or early diagnosis of LDH remains unavailable, resulting in missed opportunity for effective treatment.
Letian Shan +7 more
doaj +1 more source
Asparagine Metabolic Pathways in Arabidopsis [PDF]
Plant and Cell Physiology, 2015 Inorganic nitrogen in the form of ammonium is assimilated into asparagine via multiple steps involving glutamine synthetase (GS), glutamate synthase (GOGAT), aspartate aminotransferase (AspAT) and asparagine synthetase (AS) in Arabidopsis. The asparagine amide group is liberated by the reaction catalyzed by asparaginase (ASPG) and also the amino group ...
Gaufichon, Laure +2 more
openaire +4 more sources
Structural Kinetic Modeling of Metabolic Networks [PDF]
, 2006 To develop and investigate detailed mathematical models of cellular metabolic processes is one of the primary challenges in systems biology. However, despite considerable advance in the topological analysis of metabolic networks, explicit kinetic ...
B. Blasius +19 more
core +2 more sources