Results 11 to 20 of about 1,077,952 (298)
Metabolic reprogramming in osteosarcoma
Pediatric Discovery, 2023 Tumor cells undergo metabolic reprogramming to meet their energy and anabolic demands to maintain their malignant phenotype. Activation of oncogenes and deletion of tumor suppressors promotes metabolic reprogramming in cancer by directly or indirectly ...
Yulu Shi, Xiaohan Yue, Qing Luo
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Metabolic Reprogramming in COVID-19 [PDF]
International Journal of Molecular Sciences, 2021 Plenty of research has revealed virus induced alternations in metabolic pathways, which is known as metabolic reprogramming. Studies focusing on COVID-19 have uncovered significant changes in metabolism, resulting in the perspective that COVID-19 is a ...
Tingting Wang, Tao Shen
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Metabolic reprogramming in efferocytosis [PDF]
Frontiers in Cell and Developmental BiologyEfferocytosis refers to the process by which phagocytes specifically identify and eliminate apoptotic cells. This process is essential for both maintaining tissue homeostasis and suppressing inflammatory responses, as well as facilitating tissue repair ...
Yingying Xi +6 more
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Metabolic Reprogramming of Cancer Cells during Tumor Progression and Metastasis
Metabolites, 2021 Cancer cells face various metabolic challenges during tumor progression, including growth in the nutrient-altered and oxygen-deficient microenvironment of the primary site, intravasation into vessels where anchorage-independent growth is required, and ...
Kenji Ohshima, Eiichi Morii
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MYCN and Metabolic Reprogramming in Neuroblastoma
Cancers, 2022 Neuroblastoma is a pediatric cancer responsible for approximately 15% of all childhood cancer deaths. Aberrant MYCN activation, as a result of genomic MYCN amplification, is a major driver of high-risk neuroblastoma, which has an overall survival rate of
Han-Fei Ding +5 more
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Nrf2-Mediated Metabolic Reprogramming in Cancer [PDF]
Oxidative Medicine and Cellular Longevity, 2018 Metabolic reprogramming is one of the hallmarks of cancer. Nrf2 pathway is one of the critical signaling cascades involved in cell defense and survival against oxidative stress. The significance of Nrf2 in cancer metabolism begins to be recognized.
Juan Chen +4 more
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The role of metabolic reprogramming in kidney cancer [PDF]
Frontiers in OncologyMetabolic reprogramming is a cellular process in which cells modify their metabolic patterns to meet energy requirements, promote proliferation, and enhance resistance to external stressors.
Ziyi Chen +3 more
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Mitochondrial metabolic reprogramming in diabetic kidney disease
Cell Death and DiseaseDiabetic kidney disease, known as a glomerular disease, arises from a metabolic disorder impairing renal cell function. Mitochondria, crucial organelles, play a key role in substance metabolism via oxidative phosphorylation to generate ATP. Cells undergo
Xiaoting Fan +8 more
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Metabolic reprogramming in the arsenic carcinogenesis
Ecotoxicology and Environmental Safety, 2022 Chronic exposure to arsenic has been associated with a variety of cancers with the mechanisms undefined. Arsenic exposure causes alterations in metabolites in bio-samples.
Yihui Ruan +10 more
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Metabolic reprogramming in cholangiocarcinoma [PDF]
Journal of Hepatology, 2022 Metabolic reprogramming is a hallmark of cancer and allows tumour cells to meet the increased energy demands required for rapid proliferation, invasion, and metastasis. Indeed, many tumour cells acquire distinctive metabolic and bioenergetic features that enable them to survive in resource-limited conditions, mainly by harnessing alternative nutrients.
Chiara Raggi +4 more
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