Results 11 to 20 of about 123,701 (265)
Metabolic reprogramming in the arsenic carcinogenesis
Ecotoxicology and Environmental Safety, 2022 Chronic exposure to arsenic has been associated with a variety of cancers with the mechanisms undefined. Arsenic exposure causes alterations in metabolites in bio-samples.
Yihui Ruan +10 more
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Metabolic reprogramming in cholangiocarcinoma [PDF]
Journal of Hepatology, 2022 Metabolic reprogramming is a hallmark of cancer and allows tumour cells to meet the increased energy demands required for rapid proliferation, invasion, and metastasis. Indeed, many tumour cells acquire distinctive metabolic and bioenergetic features that enable them to survive in resource-limited conditions, mainly by harnessing alternative nutrients.
Chiara Raggi +4 more
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Metabolic Reprogramming of Liver Fibrosis [PDF]
Cells, 2021 Liver fibrosis is an excessive and imbalanced deposition of fibrous extracellular matrix (ECM) that is associated with the hepatic wound-healing response. It is also the common mechanism that contributes to the impairment of the liver function that is observed in many chronic liver diseases (CLD).
M. Eugenia Delgado +3 more
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Metabolic reprogramming in osteosarcoma
Pediatric Discovery, 2023 AbstractTumor cells undergo metabolic reprogramming to meet their energy and anabolic demands to maintain their malignant phenotype. Activation of oncogenes and deletion of tumor suppressors promotes metabolic reprogramming in cancer by directly or indirectly regulating enzymatic activities associated with metabolic pathways. Metabolic reprogramming in
Yulu Shi, Xiaohan Yue, Qing Luo
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Metabolic Reprogramming in COVID-19 [PDF]
International Journal of Molecular Sciences, 2021 Plenty of research has revealed virus induced alternations in metabolic pathways, which is known as metabolic reprogramming. Studies focusing on COVID-19 have uncovered significant changes in metabolism, resulting in the perspective that COVID-19 is a metabolic disease.
Shen, Tao, Wang, Tingting
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Metabolic reprogramming of the tumor [PDF]
Oncogene, 2012 Cancer is classically considered as a genetic and, more recently, epigenetic multistep disease. Despite seminal studies in the 1920s by Warburg showing a characteristic metabolic pattern for tumors, cancer bioenergetics has often been relegated to the backwaters of cancer biology.
Ferreira, LM +2 more
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Metabolic reprogramming in prostate cancer [PDF]
British Journal of Cancer, 2021 AbstractAlthough low risk localised prostate cancer has an excellent prognosis owing to effective treatments, such as surgery, radiation, cryosurgery and hormone therapy, metastatic prostate cancer remains incurable. Existing therapeutic regimens prolong life; however, they are beset by problems of resistance, resulting in poor outcomes.
Fahim Ahmad +2 more
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Metabolic Reprogramming in Glioma [PDF]
Frontiers in Cell and Developmental Biology, 2017 Many cancers have long been thought to primarily metabolize glucose for energy production-a phenomenon known as the Warburg Effect, after the classic studies of Otto Warburg in the early twentieth century. Yet cancer cells also utilize other substrates, such as amino acids and fatty acids, to produce raw materials for cellular maintenance and energetic
Strickland, Marie, Stoll, Elizabeth A.
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Metabolic reprogramming in macrophage responses [PDF]
Biomarker Research, 2021 AbstractMacrophages are critical mediators of tissue homeostasis, with the function of tissue development and repair, but also in defense against pathogens. Tumor-associated macrophages (TAMs) are considered as the main component in the tumor microenvironment and play an important role in tumor initiation, growth, invasion, and metastasis.
Yang Liu +9 more
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Immune cell metabolism and metabolic reprogramming
Molecular Biology Reports, 2022 Energy metabolism maintains the activation of intracellular and intercellular signal transduction, and plays a crucial role in immune response. Under environmental stimulation, immune cells change from resting to activation and trigger metabolic reprogramming. The immune system cells exhibit different metabolic characteristics when performing functions.
Chenchen Hu +5 more
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