Results 11 to 20 of about 1,437,206 (304)
Metabolic Plasticity in Chemotherapy Resistance [PDF]
Frontiers in Oncology, 2020 Resistance of cancer cells to chemotherapy is the first cause of cancer-associated death. Thus, new strategies to deal with the evasion of drug response and to improve clinical outcomes are needed.
Maria Andrea Desbats +5 more
doaj +3 more sources
Metabolic checkpoint of ferroptosis resistance [PDF]
Molecular & Cellular Oncology, 2021 The metabolic checkpoint of ferroptosis remains obscure. We find that glucose favors system xc− inhibitor-induced ferroptosis by activating pyruvate oxidation, thereby promoting fatty acid synthesis and subsequent lipid peroxidation.
Jiao Liu, Rui Kang, Daolin Tang
doaj +3 more sources
Metabolic mechanisms of immunotherapy resistance [PDF]
Exploration of Targeted Anti-tumor TherapyImmunotherapy has revolutionized cancer treatment, yet its efficacy is frequently compromised by metabolic mechanisms that drive resistance. Understanding how tumor metabolism shapes the immune microenvironment is essential for developing effective ...
Luis Cabezón-Gutiérrez +4 more
doaj +3 more sources
Metabolic Resistance in Bed Bugs [PDF]
Insects, 2011 Blood-feeding insects have evolved resistance to various insecticides (organochlorines, pyrethroids, carbamates, etc.) through gene mutations and increased metabolism. Bed bugs (Cimex lectularius) are hematophagous ectoparasites that are poised to become
Omprakash Mittapalli +2 more
doaj +3 more sources
Pyrethroid Resistance Aggravation in Ugandan Malaria Vectors Is Reducing Bednet Efficacy
Pathogens, 2021 Monitoring cases of insecticide resistance aggravation and the effect on the efficacy of control tools is crucial for successful malaria control. In this study, the resistance intensity of major malaria vectors from Uganda was characterised and its ...
Magellan Tchouakui +7 more
doaj +1 more source
Biology, 2023 Large crabgrass (Digitaria sanguinalis (L.) Scop.) is one of the major malignant grass weeds in Chinese maize (Zea mays L.) fields, and it has recently developed resistance to the acetolactate synthase (ALS)-inhibiting herbicide nicosulfuron.
Xumiao Wang +6 more
doaj +1 more source
Metabolic regulation of antibiotic resistance [PDF]
FEMS Microbiology Reviews, 2011 It is generally assumed that antibiotics and resistance determinants are the task forces of a biological warfare in which each resistance determinant counteracts the activity of a specific antibiotic. According to this view, antibiotic resistance might be considered as a specific response to an injury, not necessarily linked to bacterial metabolism ...
Martínez, José L., Rojo, Fernando
openaire +2 more sources
Insects, 2021 Cacopsylla pyri (L.) (Hemiptera: Psyllidae) is a key pest of pear orchards in Spain. The large number of insecticide treatments necessary for control may be an important contributor to the emergence of resistance.
Dolors Bosch-Serra +4 more
doaj +1 more source
Divergences in insulin resistance between the different phenotypes of the polycystic ovary syndrome [PDF]
, 2013 Context/Objective: Current diagnostic criteria for polycystic ovary syndrome (PCOS) have generated distinct PCOS phenotypes, based on the different combinations of diagnostic features found in each patient.
Bonin, Cecilia +12 more
core +1 more source
Antiangiogenic resistance via metabolic symbiosis [PDF]
Molecular & Cellular Oncology, 2016 Several types of tumor are currently treated with antiangiogenic drugs. Unfortunately, most of these patients develop therapy resistance and succumb to the disease. Recently, a novel mechanism of resistance to antiangiogenics involving metabolic symbiosis of tumor cells has been described.
Gabriela Jiménez-Valerio +1 more
openaire +2 more sources