Mechanism of Resistance to Pyroxsulam in Multiple-Resistant Alopecurus myosuroides from China
Black grass (Alopecurus myosuroides Huds.) is a highly competitive weed in winter wheat fields of China. Due to repeated use of acetolactate synthase (ALS) inhibitors, many A.
Yuning Lan +7 more
doaj +1 more source
Early postnatal caloric restriction protects adult male intrauterine growth-restricted offspring from obesity. [PDF]
Postnatal ad libitum caloric intake superimposed on intrauterine growth restriction (IUGR) is associated with adult-onset obesity, insulin resistance, and type 2 diabetes mellitus (T2DM).
Dai, Yun +6 more
core +1 more source
The use of chemical insecticides continues to play a major role in the control of disease vector populations, which is leading to the global dissemination of insecticide resistance.
Isabela Reis Montella +2 more
doaj +1 more source
Ironing out the details: Untangling dietary iron and genetic background in diabetes [PDF]
The search for genetic risk factors in type-II diabetes has been hindered by a failure to consider dietary variables. Dietary nutrients impact metabolic disease risk and severity and are essential to maintaining metabolic health.
Lawson, Heather A, Miranda, Mario A
core +2 more sources
Cancer Metabolism and Drug Resistance [PDF]
Metabolic alterations, driven by genetic and epigenetic factors, have long been known to be associated with the etiology of cancer. Furthermore, accumulating evidence suggest that cancer metabolism is intimately linked to drug resistance, which is currently one of the most important challenges in cancer treatment. Altered metabolic pathways help cancer
Mahbuba Rahman, Mohammad Rubayet Hasan
openaire +3 more sources
T regulatory lymphocytes and endothelial function in pediatric obstructive sleep apnea. [PDF]
BackgroundObstructive sleep apnea (OSA) is a low-grade inflammatory disease affecting the cardiovascular and metabolic systems. Increasing OSA severity reduces T-regulatory lymphocytes (Tregs) in OSA children. Since Tregs modulate endothelial activation,
Bandla, Hari PR +8 more
core +6 more sources
Model for metabolic resistance against ALS inhibitors
Due to herbicide selection pressure metabolic resistance has evolved in many weed species. In this paper we analyse the interaction between the branched chain amino acid (BBC) pathway and detoxifying pathways for herbicide breakdown.
Richter, Otto +2 more
doaj +1 more source
Class III PI3K regulates organismal glucose homeostasis by providing negative feedback on hepatic insulin signalling. [PDF]
Defective hepatic insulin receptor (IR) signalling is a pathogenic manifestation of metabolic disorders including obesity and diabetes. The endo/lysosomal trafficking system may coordinate insulin action and nutrient homeostasis by endocytosis of IR and ...
Burnol, Anne-Françoise +7 more
core +1 more source
Resistance risk assessment of the novel complex II inhibitor pyflubumide in the polyphagous pest Tetranychus urticae [PDF]
Pyflubumide is a novel selective carboxanilide acaricide that inhibits mitochondrial complex II of spider mite species such as Tetranychus urticae. We explored the baseline toxicity and potential cross-resistance risk of pyflubumide in a reference panel ...
Fotoukkiaii, Seyedeh Masoumeh +3 more
core +1 more source
Metabolic flexibility and insulin resistance
Metabolic flexibility is the capacity for the organism to adapt fuel oxidation to fuel availability. The inability to modify fuel oxidation in response to changes in nutrient availability has been implicated in the accumulation of intramyocellular lipid and insulin resistance.
Galgani Fuentes, José +2 more
openaire +4 more sources

