Results 51 to 60 of about 4,435,982 (345)

Pediatric metabolic syndrome

The Nurse Practitioner, 2019
Abstract: Although the prevalence of obesity and its related complications are increasing among pediatric patients, appropriate management can prevent chronic disease. This article will present an overview of metabolic syndrome, pediatric metabolic syndrome guidelines, pathophysiology, associated risk factors, and clinical practice ...
Abigail, Felix, Rita Marie, John
openaire   +3 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Fabrication and application of cisplatin-loaded mesoporous magnetic nanobiocomposite: a novel approach to smart cervical cancer chemotherapy

Cancer Nanotechnology, 2022
There are significant challenges in developing drug carriers for therapeutic perspective. We have investigated a novel nanocarrier system, based on combining functionalized magnetic nanocomposite with Metal–Organic Frameworks (MOFs).
Mahdieh Darroudi, Seyedeh Elnaz Nazari, Fereshteh Asgharzadeh, Nima Khalili-Tanha, Ghazaleh Khalili-Tanha, Toktam Dehghani, Maryam Karimzadeh, Mina Maftooh, Gordon A. Fern, Amir Avan, Majid Rezayi, Majid Khazaei   +11 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

The relationship between daytime napping and obesity: a systematic review and meta-analysis

Scientific Reports, 2023
Daytime napping, a habit widely adopted globally, has an unclear association with obesity. In this study, we executed a meta-analysis to explore the relationship between daytime napping and obesity.
Zixin Cai, Yan Yang, Jingjing Zhang, Yu Liu   +3 more
doaj   +1 more source

Metabolic Syndrome: Past, Present and Future

Nutrients, 2020
Most clinicians and health professionals have heard or read about metabolic syndrome [...].
I. Lemieux, J. Despres
semanticscholar   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

The impacts of Crocin on serum cytokines concentrations in participants with metabolic syndrome: a double-blind randomized clinical trial study

Scientific Reports
The aim of this study was to investigate the effect of Crocin on the inflammatory cytokines profile in patients with Metabolic syndrome (Mets). Twenty-eight patients with Mets (15 cases and 13 controls) were randomly selected by the International ...
Razie Rezaiee, Hamideh Ghazizadeh, Susan Darroudi, Roshanak Ghaffarian Zirak, Mohadese Rohban, Marziyeh Eidi, Irandokht Nikbakht Jam, Ali Asghar Mahmoudi, Farzin Hadizadeh, Malihe Aghasizadeh, Abbas Mohtashamian, Majid Ghayour-Mobarhan   +11 more
doaj   +1 more source

Time-Restricted Feeding Prevents Obesity and Metabolic Syndrome in Mice Lacking a Circadian Clock.

Cell Metabolism, 2019
Increased susceptibility of circadian clock mutant mice to metabolic diseases has led to the idea that a molecular clock is necessary for metabolic homeostasis. However, these mice often lack a normal feeding-fasting cycle.
A. Chaix, Terry Lin, H. Le, M. Chang, Satchidananda Panda   +4 more
semanticscholar   +1 more source

Role of Hyperinsulinemia and Insulin Resistance in Hypertension: Metabolic Syndrome Revisited.

Canadian Journal of Cardiology, 2020
Hyperinsulinemia and insulin resistance were proposed more than 30 years ago to be important contributors to elevated blood pressure (BP) associated with obesity and the metabolic syndrome, also called syndrome X.
A. D. da Silva, Jussara M. do Carmo, Xuan Li, Zhen Wang, A. Mouton, J. Hall   +5 more
semanticscholar   +1 more source