Muscle atrophy due to limb immobilization and inactivity is a common consequence of many diseases and treatment processes. One of the systems activated in inflammatory conditions is the renin-angiotensin system (RAS). The present study was conducted with
Sima Seifi+11 more
doaj +1 more source
Protein corona critically affects the bio-behaviors of SARS-CoV-2 [PDF]
The outbreak of the coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has become a worldwide public health crisis. When the SARS-CoV-2 enters the biological fluids in the human body, different types of biomolecules (in particular proteins) may adsorb on its surface and alter its infection ability.
arxiv
The diagnostic and prognostic value of C1orf174 in colorectal cancer [PDF]
Introduction: Colorectal cancer (CRC) is among the lethal cancers, indicating the need for the identification of novel biomarkers for the detection of patients in earlier stages.
Elham Nazari+18 more
doaj +1 more source
Discovering topic structures of a temporally evolving document corpus [PDF]
In this paper we describe a novel framework for the discovery of the topical content of a data corpus, and the tracking of its complex structural changes across the temporal dimension. In contrast to previous work our model does not impose a prior on the rate at which documents are added to the corpus nor does it adopt the Markovian assumption which ...
arxiv
Strabismic syndromes and syndromic strabismus - a brief review [PDF]
Strabismus can be found in association with congenital heart diseases, for examples, in velocardiofacial (DiGeorge) syndrome, Down syndrome, mild dysmorphic features, in CHARGE association, Turner syndrome, Ullrich-Turner syndrome, cardiofaciocutaneous syndrome.1-4 Some types of strabismus is heritable (e.g.
arxiv
Oxysterols in Vascular Cells and Role in Atherosclerosis [PDF]
Atherosclerosis is a major cardiovascular complication of diseases associated with elevated oxidative stress such as type 2 diabetes and metabolic syndrome. In these situations, low density lipoproteins (LDL) undergo oxidation. Oxidized LDL display proatherogenic activities through multiple and complex mechanisms which lead to dysfunctions of vascular ...
arxiv +1 more source
mTOR signaling in Brown and Beige adipocytes: implications for thermogenesis and obesity
Brown and beige adipocytes are mainly responsible for nonshivering thermogenesis or heat production, despite the fact that they have distinguished features in distribution, developmental origin, and functional activation.
Yuqing Ye+3 more
doaj +1 more source
Reply to: vitamin D supplementation and hemoglobin: dosing matters in prevention/treatment of anemia
Seyyed Mostafa Arabi+3 more
doaj +1 more source
Preoperative Vitamin.D Status and Post-Total Thyroidectomy Hypocalcemia [PDF]
Introduction: Hypocalcemia is a common complication of total thyroidectomy (TT). This study was designed to investigate the effect of preoperative vitamin.D (Vit.D) status on the occurrence of post-total thyroidectomy hypocalcemia.Materials and Methods ...
Parvin Layegh+5 more
doaj +1 more source
Peptide strings clues to the genesis and treatment of rheumatoid arthritis: rebuilding self-protective immunity amid fungal ruins [PDF]
A recent application of the peptide strings concept has yielded novel perceptions on cell growth regulation, for instance that of oncoprotein metastasis. Here, this interdisciplinary approach at the boundary between physics and biology has been applied to gain a more profound insight into rheumatoid arthritis.
arxiv