Results 81 to 90 of about 6,426,940 (341)

Circadian rhythms and the gut microbiota: from the metabolic syndrome to cancer

Nature Reviews Endocrinology, 2020
The metabolic syndrome is prevalent in developed nations and accounts for the largest burden of non-communicable diseases worldwide. The metabolic syndrome has direct effects on health and increases the risk of developing cancer.
F. Bishehsari, R. Voigt, A. Keshavarzian
semanticscholar   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Association between isolated minor ST-segment and T wave changes with 10 years all-cause and stroke mortality

Scientific Reports
Minor ST segment and T wave (ST-T) abnormalities are commonly seen on the resting electrocardiograms (ECGs) of healthy individuals, but the long-term effects of these findings, particularly in the general population, have not been thoroughly assessed. As
Sara Saffar Soflaei, Farima Farsi, Alireza Heidari-Bakavoli, Marzieh Kohantorabi, Parsa Mearaji Far, Reza Eftekhar, Reyhaneh Saffar-Khorasani, Habibollah Esmaily, Gordon A. Ferns, Mohesn Moohebati#, Majid Ghayour Mobarhan#, Mohsen Moohebati, Majid Ghayour-Mobarhan   +12 more
doaj   +1 more source

Obesity, metabolic syndrome, and primary hypertension

Pediatric nephrology (Berlin, West), 2020
Primary hypertension is the dominant form of arterial hypertension in adolescents. Disturbed body composition with, among other things, increased visceral fat deposition, accelerated biological maturation, metabolic abnormalities typical for metabolic ...
M. Litwin, Z. Kułaga
semanticscholar   +1 more source

Pediatric Mediastinal Gray Zone Lymphoma With Germline TET2 Heterozygous Variant

Pediatric Blood &Cancer, EarlyView.
Matthew R. Schuelke, Julia Wang, Haley Newman, Evelyn Kurpiewski, Anne Reilly, Susan R. Rheingold, Gerald Wertheim, Moe Takeda, Daniel J. Zheng, Kaitlin Devine   +9 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Nutrients and pharmacological management of Metabolic syndrome

, 2021
Metabolic syndrome is a public health problem defined by a cluster of interconnected components that increase the risk of cardiovascular atherosclerotic diseases and T2DM.
Ghim, Nayoung
core  

Emerging roles of TRIO and F-actin-binding protein in human diseases

Cell Communication and Signaling, 2018
TRIO and F-actin-binding protein (TRIOBP) also referred to as Tara, was originally isolated as a cytoskeleton remodeling protein. TRIOBP-1 is important for regulating F-actin filament reorganization. TRIOBP variants are broadly classified as variant-1 or 
Sungjin Park, Hyunji Lee, Minhee Kim, Jisoo Park, Seon-Hwan Kim, Jongsun Park   +5 more
doaj   +1 more source

Bone morphogenetic protein 2 is a new molecular target linked to non-alcoholic fatty liver disease with potential value as non-invasive screening tool

Biomarker Research, 2022
Background Non-alcoholic fatty liver disease (NAFLD) is the commonest cause of chronic liver disease worldwide, being non-alcoholic steatohepatitis (NASH) its most clinically relevant form.
Patricia Marañón, Carlos Ernesto Fernández-García, Stephania C. Isaza, Esther Rey, Rocío Gallego-Durán, Rocío Montero-Vallejo, Javier Rodríguez de Cía, Javier Ampuero, Manuel Romero-Gómez, Carmelo García-Monzón, Águeda González-Rodríguez   +10 more
doaj   +1 more source

Metabolic Syndrome and Migraine [PDF]

Frontiers in Neurology, 2012
Migraine and metabolic syndrome are highly prevalent and costly conditions. The two conditions coexist, but it is unclear what relationship may exist between the two processes. Metabolic syndrome involves a number of findings, including insulin resistance, systemic hypertension, obesity, a proinflammatory state, and a prothrombotic state.
Sachdev, Amit, Marmura, Michael J
openaire   +3 more sources