Results 81 to 90 of about 342,953 (254)

The Metabolic Cardiovascular Syndrome: Syndrome X, Reavenʼs Syndrome, Insulin Resistance Syndrome, Atherothrombogenic Syndrome

open access: yesJournal of Cardiovascular Pharmacology, 1992
A short review of the metabolic cardiovascular risk syndrome (MCVS) is given. Traditionally, cardiovascular risk has been associated with three so-called "main" risk factors; hypercholesterolemia, hypertension, and smoking. In addition, the association between diabetes and cardiovascular disease has been known for many years in clinical medicine ...
openaire   +3 more sources

Oxidative stress: new insights on the association of nonalcoholic fatty liver disease and atherosclerosis [PDF]

open access: yes, 2015
Non-alcoholic fatty liver disease (NAFLD) represents the most common and emerging chronic liver disease worldwide. It includes a wide spectrum of liver diseases ranging from simple fatty liver to non-alcoholic steatohepatitis (NASH), which may progress ...
Albanese, Fabiana   +7 more
core   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento   +3 more
wiley   +1 more source

Liver Pathology and the Metabolic Syndrome X in Severe Obesity [PDF]

open access: yesThe Journal of Clinical Endocrinology & Metabolism, 1999
The metabolic syndrome X, characterized by insulin resistance, dyslipidemia, hypertension, and a male, visceral distribution of adipose tissue, is associated with increased morbidity and mortality from several prevalent diseases, such as diabetes, cancers, myocardial infarction, and stroke.
P, Marceau   +6 more
openaire   +2 more sources

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni   +19 more
wiley   +1 more source

Physiological conditions influencing regenerative potential of stem cells [PDF]

open access: yes, 2016
Stem cells are being used in the treatment of cardivovascular diseases. Here, we review the physiologic and pathologic conditions that impact the regenerative potential of stem cells in the treatment of cardiovascular diseases which include the influence
Avitabile, Daniele   +3 more
core   +1 more source

Role of Prednisone and 25‐Hydroxyvitamin D on Bone Mineral Density and Osteoporosis in Systemic Lupus Erythematosus

open access: yesArthritis Care &Research, EarlyView.
Objective We evaluated the role of 25‐hydroxyvitamin D (25[OH]D), prednisone, and other risk factors for bone mineral density (BMD) loss and osteoporosis in systemic lupus erythematosus (SLE). Methods We calculated the association between 25(OH)D levels and other potential risk factors and BMD measures (spine T scores) and osteoporosis (defined as a T ...
Nima Madanchi   +4 more
wiley   +1 more source

Association of Apolipoprotein A-V Gene Polymorphisms and Lipid Metabolism in Mongolian Patients with Metabolic Syndrome

open access: yesCentral Asian Journal of Medical Sciences, 2017
Objectives: Our study determined the genetic effect of Apolipoprotein A-V (APOA5) gene polymorphisms on lipid parameters in patients with metabolic syndrome (MetS).
Ariunbold Chuluun-Erdene   +4 more
doaj   +1 more source

The relations of metabolic syndrome to anxiety and depression symptoms in children and adults [PDF]

open access: yes, 2017
Metabolic syndrome is a cluster of five factors (elevated systolic blood pressure, elevated blood glucose, elevated triglycerides, large waist circumference, and decreased HDL) that are related to a greater chance of heart disease, stroke, and diabetes ...
Michael, Jennifer R
core   +1 more source

Effects of physical exercise on adiponectin, leptin, and inflammatory markers in childhood obesity: systematic review and meta-analysis [PDF]

open access: yes, 2018
Background: New findings on adipose tissue physiology and obesity-Associated inflammation status suggest that modification of the adipokine level can be relevant for the long-Term prevention of obesity-Associated chronic disease. Objectives: The scope of
Bianco, Antonio   +7 more
core   +2 more sources

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