Results 11 to 20 of about 5,570,553 (408)
Essays in Biochemistry, 2020 Abstract Metabolism consists of a series of reactions that occur within cells of living organisms to sustain life. The process of metabolism involves many interconnected cellular pathways to ultimately provide cells with the energy required to carry out their function.
Ayesha Judge, Michael S. Dodd
openaire +2 more sources
NAD+ Metabolism, Metabolic Stress, and Infection [PDF]
Frontiers in Molecular Biosciences, 2021 Nicotinamide adenine dinucleotide (NAD+) is an essential metabolite with wide-ranging and significant roles in the cell. Defects in NAD+ metabolism have been associated with many human disorders; it is therefore an emerging therapeutic target. Moreover, NAD+ metabolism is perturbed during colonization by a variety of pathogens, either due to the ...
Groth, Benjamin +2 more
openaire +5 more sources
Fructose Metabolism and Cardiac Metabolic Stress [PDF]
Frontiers in Pharmacology, 2021 Cardiovascular disease is one of the leading causes of mortality in diabetes. High fructose consumption has been linked with the development of diabetes and cardiovascular disease. Serum and cardiac tissue fructose levels are elevated in diabetic patients, and cardiac production of fructose via the intracellular polyol pathway is upregulated.
M. Annandale +11 more
openaire +5 more sources
Glucocorticoids, metabolism and metabolic diseases [PDF]
Molecular and Cellular Endocrinology, 2007 Since the discovery of the beneficial effects of adrenocortical extracts for treating adrenal insufficiency more than 80 years ago, glucocorticoids (GC) and their cognate, intracellular receptor, the glucocorticoid receptor (GR) have been characterized as critical components of the delicate hormonal control system that determines energy homeostasis in ...
Vegiopoulos, Alexandros, Herzig, Stephan
openaire +3 more sources
Lactate metabolism in human health and disease
Signal Transduction and Targeted Therapy, 2022 The current understanding of lactate extends from its origins as a byproduct of glycolysis to its role in tumor metabolism, as identified by studies on the Warburg effect.
Xiaolu Li +9 more
semanticscholar +1 more source
Chapter 10: Glucose control: insulin therapy
South African Family Practice, 2018 Insulin and its analogues lower blood glucose by stimulating peripheral glucose uptake, especially by skeletal muscle and fat, and by inhibiting hepatic glucose production. Insulin inhibits lipolysis and proteolysis, and enhances protein synthesis.
The Society for Endocrinology Metabolism and Diabetes of South Africa
doaj +1 more source
International Journal of Endocrinology, 2022 Background. Tenascin-C (TNC), an extracellular matrix glycoprotein, is elevated in inflammatory and cardiovascular pathologies, whereas alarin, a novel orexigenic peptide, participates in insulin resistance and glycometabolism.
Mingming Li +7 more
doaj +1 more source
Association between cognitive performance and cortical glucose metabolism in patients with mild Alzheimer's disease [PDF]
, 2005 Background: Neuronal and synaptic function in Alzheimer's disease (AD) is measured in vivo by glucose metabolism using positron emission tomography (PET). Objective: We hypothesized that neuronal activation as measured by PET is a more sensitive index of
A. Drzezga +27 more
core +1 more source
Fructose metabolism and metabolic disease [PDF]
Journal of Clinical Investigation, 2018 Increased sugar consumption is increasingly considered to be a contributor to the worldwide epidemics of obesity and diabetes and their associated cardiometabolic risks. As a result of its unique metabolic properties, the fructose component of sugar may be particularly harmful.
Herman, Mark A +3 more
openaire +2 more sources
Glucose Control: non-insulin therapies*
South African Family Practice, 2018 This chapter summarises information for each of the non-insulin drug classes that are used for blood glucose control. Each summary is accompanied by a table of recommendations to guide the clinical use of these medications.
The Society for Endocrinology Metabolism and Diabetes of South Africa
doaj +1 more source