Results 21 to 30 of about 3,690,314 (381)

NAD+ Metabolism, Metabolic Stress, and Infection [PDF]

open access: yesFrontiers in Molecular Biosciences, 2021
Nicotinamide adenine dinucleotide (NAD+) is an essential metabolite with wide-ranging and significant roles in the cell. Defects in NAD+ metabolism have been associated with many human disorders; it is therefore an emerging therapeutic target. Moreover, NAD+ metabolism is perturbed during colonization by a variety of pathogens, either due to the ...
Groth, Benjamin   +2 more
openaire   +5 more sources

Chapter 10: Glucose control: insulin therapy

open access: yesSouth African Family Practice, 2018
Insulin and its analogues lower blood glucose by stimulating peripheral glucose uptake, especially by skeletal muscle and fat, and by inhibiting hepatic glucose production. Insulin inhibits lipolysis and proteolysis, and enhances protein synthesis.
The Society for Endocrinology, Metabolism and Diabetes of South Africa
doaj   +1 more source

Identification and Functional Characterization of a Novel Variant in the SEMA3A Gene in a Chinese Family with Kallmann Syndrome

open access: yesInternational Journal of Endocrinology, 2022
Background. Kallmann syndrome (KS) is a rare genetic disease characterized by the reproductive system and olfactory dysplasia due to the defective migration of gonadotropin-releasing hormone (GnRH) neurons.
Meng Shu   +7 more
doaj   +1 more source

Chapter 29: Male sexual dysfunction in type 2 diabetes

open access: yesSouth African Family Practice, 2018
No abstract available.
Society for Endocrinology Metabolism and Diabetes of South Africa Type 2 Diabetes Guidelines Expert Committee
doaj   +1 more source

Sodium Butyrate Attenuates Diabetic Kidney Disease Partially via Histone Butyrylation Modification

open access: yesMediators of Inflammation, 2022
Inflammation and fibrosis are the important pathophysiologic processes in diabetic kidney disease (DKD), which is induced by epigenetics, especially histone posttranslational modification (HPTMs).
Tingting Zhou   +11 more
doaj   +1 more source

The Effect of Liraglutide on Epicardial Adipose Tissue in Type 2 Diabetes

open access: yesJournal of Diabetes Research, 2021
Objective. To study the effect of liraglutide on the thickness of epicardial adipose tissue (EAT) in type 2 diabetes mellitus (T2DM) patients with abdominal obesity. Methods.
Na Zhao   +6 more
doaj   +1 more source

Metabolic Games [PDF]

open access: yesFrontiers in Applied Mathematics and Statistics, 2019
Metabolic networks have been used to successfully predict phenotypes based on optimization principles. However, a general framework that would extend to situations not governed by simple optimization, such as multispecies communities, is still lacking. Concepts from evolutionary game theory have been proposed to amend the situation.
Taneli Pusa   +6 more
openaire   +5 more sources

Endoscopic Delivery Method Using a Retrieval Net for Patients with Small-Bowel Capsule Endoscopy Stagnation in the Stomach

open access: yesGastroenterology Research and Practice, 2021
With the increasing use of capsule endoscopy (CE), screening tests for the small bowel can be performed with minimal invasiveness. However, occasionally, the entire small bowel cannot be observed because of decreased peristalsis of the stomach.
Akihiko Sumioka   +10 more
doaj   +1 more source

One-carbon metabolism in cancer [PDF]

open access: yes, 2017
Cells require one-carbon units for nucleotide synthesis, methylation and reductive metabolism, and these pathways support the high proliferative rate of cancer cells.
AJ MacFarlane   +55 more
core   +1 more source

Iron Metabolism in Obesity and Metabolic Syndrome [PDF]

open access: yesInternational Journal of Molecular Sciences, 2020
Obesity is an excessive adipose tissue accumulation that may have detrimental effects on health. Particularly, childhood obesity has become one of the main public health problems in the 21st century, since its prevalence has widely increased in recent years.
Álvaro González-Domínguez   +5 more
openaire   +6 more sources

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