Results 41 to 50 of about 3,690,314 (381)
Journal of Interventional Cardiology, 2022 Objectives.The effect of insulin therapy on coronary artery disease (CAD) remains controversial. This study aimed to analyze the association between insulin resistance and the morbidity of severe CAD in type 2 diabetes mellitus (T2DM). Methods.
Jing Song +5 more
doaj +1 more source
Macromolecular crowding explains overflow metabolism in cells [PDF]
, 2016 Overflow metabolism is a metabolic phenotype of cells characterized by mixed oxidative phosphorylation (OxPhos) and fermentative glycolysis in the presence of oxygen.
Oltvai, Zoltán N., Vazquez, Alexei
core +1 more source
MicroRNAs in Metabolism and Metabolic Diseases [PDF]
Cold Spring Harbor Symposia on Quantitative Biology, 2011 Aberrant cholesterol/lipid homeostasis is linked to a number of diseases prevalent in the developed world, including metabolic syndrome, type II diabetes, and cardiovascular disease. We have previously uncovered gene regulatory mechanisms of the sterol regulatory element-binding protein (SREBP) family of transcription factors, which control the ...
S H Najafi-Shoushtari +10 more
openaire +3 more sources
Journal of Diabetes Research, 2022 Background. Few studies have specifically observed the relationship of sarcopenia, visceral obesity, or their joint effects with lean NAFLD in patients with diabetes.
Xingxing Zhang +12 more
doaj +1 more source
LC-MS proteomics analysis of the iInsulin/IGF-1-deficient Caenorhabditis elegans daf-2(e1370) mutant reveals extensive restructuring of intermediary metabolism [PDF]
, 2014 The insulin/IGF-1 receptor is a major known determinant of dauer formation, stress resistance, longevity, and metabolism in Caenorhabditis elegans. In the past, whole-genome transcript profiling was used extensively to study differential gene expression ...
Braeckman, Bart +7 more
core +2 more sources
Peripheral Blood Inflammatory Markers Can Predict Benign and Malignant Thyroid Nodules
International Journal of Endocrinology, 2022 Objective. Inflammation is related to the occurrence and development of various cancers. This study was designed to explore the role of peripheral blood platelet count, neutrophil-lymphocyte ratio (NLR), platelet count-lymphocyte count ratio (PLR ...
Yuanyuan Deng +7 more
doaj +1 more source
Final report : verification of bay productivity measurement by remote sensors [PDF]
, 2004 From University of Texas at Austin Marine Science Institute to Texas Water Development BoardInteragency cooperative contract TWDB contract no. IA03-483-003July 2004Ecosystem function in estuarine environments is known to be an important indicator of ...
Montagna, Paul A. +1 more
core +1 more source
The Dynamics of Hybrid Metabolic-Genetic Oscillators [PDF]
Chaos. 2013 Mar;23(1):013132, 2013 The synthetic construction of intracellular circuits is frequently hindered by a poor knowledge of appropriate kinetics and precise rate parameters. Here, we use generalized modeling (GM) to study the dynamical behavior of topological models of a family of hybrid metabolic-genetic circuits known as "metabolators." Under mild assumptions on the kinetics,
arxiv +1 more source
International Journal of Endocrinology, 2022 Background. Testosterone deficiency is reportedly correlated with an elevation of cholesterol in plasma, but the mechanism remains unclear. Our objective was to investigate the effects of testosterone deficiency on cholesterol metabolism and the ...
Yu Yuefeng +11 more
doaj +1 more source
International Journal of Nephrology, 2022 Background. Acute kidney injury (AKI) is a common complication of COVID-19. Several etiologies have been identified, including pigment deposition likely associated with myopathic damage. Nevertheless, the relationship between longitudinal creatine-kinase
Juan M. Soto-Fajardo +8 more
doaj +1 more source