Results 101 to 110 of about 639,967 (307)

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Salmonella Typhi and Salmonella Paratyphi A elaborate distinct systemic metabolite signatures during enteric fever. [PDF]

, 2014
The host-pathogen interactions induced by Salmonella Typhi and Salmonella Paratyphi A during enteric fever are poorly understood. This knowledge gap, and the human restricted nature of these bacteria, limit our understanding of the disease and impede the
Thanh, TH, Elin Näsström, Ha Thanh, T, Baker, S, Dolecek, Christiane, Antti, H, Karkey, A, Voong Vinh, P, Thieu, Nga Tran Vu, Stephen Baker, Vinh, Phat Voong, Thieu, NTV, Amit Arjyal, Vinh, PV, Näsström, E, Thwaites, Guy, Vu Thieu, Nga Tran, Anders Johansson, Thwaites, G, Antti, Henrik, Guy Thwaites, Johansson, A, Arjyal, A, Karkey, Abhilasha, Ha Thanh, Tuyen, Buddha Basnyat, Vu Thieu, NT, Basnyat, B, Basnyat, Buddha, Arjyal, Amit, Sabina Dongol, Abhilasha Karkey, Johansson, Anders, Tuyen Ha Thanh, Henrik Antti, Näsström, Elin,, Phat Voong Vinh, Dongol, S, Voong Vinh, Phat, Thanh, Tuyen Ha, Johansson, Anders,, Dongol, Sabina, Nga Tran Vu Thieu, Dolecek, C, Näsström, Elin, Antti, Henrik,, Baker, Stephen, Christiane Dolecek   +47 more
core   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Photodecomposition and Bioconcentration of a Bisphenol A Metabolite in Medaka, Oryzias latipes [PDF]

, 2004
Exposure experiments in medaka and photodecomposition tests were performed using a metabolite of bisphenol A [4-methyl-2,4-bis(p-hydroxyphenyl)-pent-1-ene; MBP], the solubility limit of which is 42 mg/l of water.
Miki Shimazu, Koji Arizono, Ishibashi, Hiroshi, Ishibashi, Yasuhiro, Yuji Takao, Shinich Yoshihara, Nagae, Masaki, Yoshihara, Shinich, Arizono, Koji, Hiroshi Ishibashi, Yasuhiro Ishibashi, Kohra, Shinya, Shinya Kohra, Takao, Yuji, Masaki Nagae, Nobuaki Tominaga, Tominaga, Nobuaki, Shimazu, Miki   +17 more
core   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Metabolomics analysis of CEF cells infected with avian leukosis virus subgroup J based on UHPLC-QE-MS

Poultry Science
: Avian leukosis virus subgroup J (ALV-J) is a retrovirus that can cause immunosuppression and tumors in chicken. However, relative pathogenesis is still not clear.
Menglu Xu, Kun Qian, Hongxia Shao, Yongxiu Yao, Venugopal Nair, Jianqiang Ye, Aijian Qin   +6 more
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Metabolite SERS fingerprints: Fityk .fit and .peaks files

Two folders containing .fit and .peaks from Fityk software. Files are regarding the SERS (Surface-Enhanced Raman Spectroscopy) spectra of metabolites, published by Sherman et al.
Amelia Carolina Sparavigna
core   +1 more source

Estrogenic Potency of a Bisphenol A Metabolite on Vitellogenin Synthesis in Medaka, Oryzias latipes [PDF]

, 2005
We investigated the estrogenic activity of a bisphenol A (BPA) metabolite (4-methyl-2,4-bis(p-hydroxyphenyl)-pent-1-ene; MBP) in male medaka (Oryzias latipes) using vitellogenin (Vg, Vg1 and Vg2) as a biomarker.
Inoue, Mihoka, Ishibashi, Yasuhiro, Yoshihara, Shin'Ichi, Kohra, Shinya, Shiroyama, Ken'Ichirou, Hara, Akihiko, Takao, Yuji, Tominaga, Nobuaki, Nagae, Masaki, Arizono, Koji   +9 more
core   +1 more source

Pre-Analytical Factors that Affect Metabolite Stability in Human Urine, Plasma, and Serum: A Review

Metabolites, 2019
Metabolomics provides a comprehensive assessment of numerous small molecules in biological samples. As it integrates the effects of exogenous exposures, endogenous metabolism, and genetic variation, metabolomics is well-suited for studies examining ...
Victoria L. Stevens, Elise Hoover, Ying Wang, Krista A. Zanetti   +3 more
doaj   +1 more source