Results 111 to 120 of about 1,692 (289)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Determination of the energetic value of corn, soybean meal and micronized full fat soybean for newly hatched chicks

Brazilian Journal of Poultry Science, 2004
There are some evidences described in the literature showing reduced energy metabolizability of ingredients for newly hatched chicks. Hence, a metabolism trial was carried out with the objective of determining the metabolizable energy of corn grain ...
FA Longo, JFM Menten, AA Pedroso, AN Figueiredo, AMC Racanicci, JB Gaiotto, JOB Sorbara   +6 more
doaj   +1 more source

True Metabolizable Energy of Corn Fractions

Journal of Applied Poultry Research, 1994
Abstract A series of studies was conducted to determine the relative metabolizable energy content of whole corn kernels, broken corn (BC), and foreign material (FM). Samples of yellow corn were obtained from eight different trains and separated into the three fractions which were assayed for proximate composition and nitrogen corrected true ...
Nick Dale, Donald Jackson
openaire   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Moringa leaf meal in diets of slow-growing chickens on metabolizability, performance, carcass, organ biometry and meat colorimetry [PDF]

Revista Brasileira de Saúde e Produção Animal
Two investigations were developed. The first experiment was to determine the metabolizability of Moringa (Moringa oleifera) leaf meal. 120 slow-growing, 21-day-old chickens were used.
José Virgilio Aguilar VÁSQUEZ, Roberta Gomes Marçal Vieira VAZ, Shayanne Batista MACHADO, Kênia Ferreira RODRIGUES, Caroliny Costa ARAÚJO, William Celis PINEDO   +5 more
doaj   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

EFFECT OF RICE DISTILLER DRIED GRAIN WITH SOLUBLES ON GROWTH PERFORMANCE, NUTRIENTS METABOLIZABILITY AND HAEMATO-BIOCHEMISTRY IN BROILER CHICKEN [PDF]

Exploratory Animal and Medical Research
The present study was carried out to investigate the effect of dietary inclusion of rice distiller dried grain with solubles on growth performance, nutrients metabolizability and haemato-biochemistry in broiler chicken.
Bikas Ch. Debnath
doaj   +1 more source

Apparent Metabolizable Energy of Glycerin for Broiler Chickens

Poultry Science, 2008
Three energy balance experiments were conducted to determine AMEn of glycerin using broiler chickens of diverse ages. In experiment 1, two dietary treatments were fed from 4 to 11 d of age. Dietary treatments consisted of a control diet (no added glycerin) and a diet containing 6% glycerin (94% control diet + 6% glycerin).
W A, Dozier, B J, Kerr, A, Corzo, M T, Kidd, T E, Weber, K, Bregendahl, K, Bregendal   +6 more
openaire   +2 more sources

Evaluation of agro-industrial by-products as protein sources for duck production in the Mekong Delta of Vietnam [PDF]

, 2005
This thesis is based on four studies to determine the nutritive value and ileal and total tract amino acid digestibility of agro-industrial by-products, and the effects of inclusion of these by-products in diets on the biological performance of growing ...
Nguyen, Thi Kim Dong
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source