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Systematic Analysis of Impact of Sampling Regions and Storage Methods on Fecal Gut Microbiome and Metabolome Profiles [PDF]
The contribution of human gastrointestinal (GI) microbiota and metabolites to host health has recently become much clearer. However, many confounding factors can influence the accuracy of gut microbiome and metabolome studies, resulting in ...
Yali Liang+10 more
doaj +3 more sources
The gut microbiome-metabolome dataset collection: a curated resource for integrative meta-analysis
Integrative analysis of microbiome and metabolome data obtained from human fecal samples is a promising avenue for better understanding the interplay between bacteria and metabolites in the human gut, in both health and disease.
Efrat Muller+2 more
doaj +2 more sources
HMDB 5.0: the Human Metabolome Database for 2022
The Human Metabolome Database or HMDB (https://hmdb.ca) has been providing comprehensive reference information about human metabolites and their associated biological, physiological and chemical properties since 2007. Over the past 15 years, the HMDB has
D. Wishart+36 more
semanticscholar +1 more source
For large-scale metabolomics, such as in cohort studies, normalization protocols using quality control (QC) samples have been established when using data from gas chromatography and liquid chromatography coupled to mass spectrometry.
Hiroyuki Yamamoto+8 more
doaj +1 more source
The long-term effect of a plant (P)-based diet was assessed by proton nuclear magnetic resonance (1H-NMR) metabolomics in rainbow trout fed a marine fish meal (FM)–fish oil (FO) diet (M), a P-based diet and a control commercial-like diet (C) starting ...
Catherine Deborde+7 more
doaj +1 more source
The core metabolome and root exudation dynamics of three phylogenetically distinct plant species
Root exudates display a diurnal signature, change with growth environment, and can be divided into a core metabolome common to multiple plant species, and specialized exudates produced by distinct species.
Sarah McLaughlin+4 more
semanticscholar +1 more source
Blood metabolome is commonly used in human studies to explore the associations of gut microbiota-derived metabolites with cardiometabolic diseases. Here, in a cohort of 1007 middle-aged and elderly adults with matched fecal metagenomic (149 species and ...
Kui Deng+12 more
semanticscholar +1 more source
Human metabolome variation along the upper intestinal tract
Most processing of the human diet occurs in the small intestine. Metabolites in the small intestine originate from host secretions, plus the ingested exposome^ 1 and microbial transformations.
J. Folz+8 more
semanticscholar +1 more source
An understanding of the changes in gut microbiome composition and its associated metabolic functions is important to assess the potential implications thereof on host health.
Aishwarya Murali+12 more
doaj +1 more source
Faecal metabolome and its determinants in inflammatory bowel disease
Objective Inflammatory bowel disease (IBD) is a multifactorial immune-mediated inflammatory disease of the intestine, comprising Crohn’s disease and ulcerative colitis.
A. Vich Vila+16 more
semanticscholar +1 more source