Results 1 to 10 of about 50 (50)

The Bovine Metabolome [PDF]

Metabolites, 2020
From an animal health perspective, relatively little is known about the typical or healthy ranges of concentrations for many metabolites in bovine biofluids and tissues. Here, we describe the results of a comprehensive, quantitative metabolomic characterization of six bovine biofluids and tissues, including serum, ruminal fluid, liver, Longissimus ...
Hamed Piri-Moghadam, Carolyn Fitzsimmons, Carolyn Fitzsimmons, Rupasri Mandal, David S. Wishart, Jiamin Zheng, Carin Li, An Chi Guo, Le Luo Guan, Aidin Foroutan   +9 more
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Metabolomics in Otorhinolaryngology

Frontiers in Molecular Biosciences, 2022
Otorhinolaryngology (Ear, Nose and Throat-ENT) focuses on inflammatory, immunological, infectious, and neoplastic disorders of the head and neck and on their medical and surgical therapy. The fields of interest of this discipline are the ear, the nose and its paranasal sinuses, the oral cavity, the pharynx, the larynx, and the neck.
Noto, Antonio, Piras, Cristina, Atzori, Luigi, Mussap, Michele, Albera, Andrea, Albera, Roberto, Casani, Augusto Pietro, Capobianco, Silvia, Fanos, Vassilios   +8 more
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Metabolomics [PDF]

Cell Metabolism, 2007
Metabolomics is the systematic identification and quantitation of all metabolites in a given organism or biological sample. The enhanced resolution provided by nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS), along with powerful chemometric software, allows the simultaneous determination and comparison of thousands of chemical ...
Idle, Jeffrey R., Gonzalez, Frank J.
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PLS2 in Metabolomics [PDF]

Metabolites, 2019
Metabolomics is the systematic study of the small-molecule profiles of biological samples produced by specific cellular processes. The high-throughput technologies used in metabolomic investigations generate datasets where variables are strongly correlated and redundancy is present in the data.
Matteo Stocchero, Emanuela Locci, Ernesto d’Aloja, Matteo Nioi, Eugenio Baraldi, Giuseppe Giordano   +5 more
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Cancer Metabolomics and the Human Metabolome Database [PDF]

Metabolites, 2016
The application of metabolomics towards cancer research has led to a renewed appreciation of metabolism in cancer development and progression. It has also led to the discovery of metabolite cancer biomarkers and the identification of a number of novel cancer causing metabolites.
Avalyn Stanislaus, Miguel Ramirez-Gaona, Rupasri Mandal, David S. Wishart   +3 more
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Metabolomics in oncology

Cancer Reports, 2023
AbstractBackgroundOncogenic transformation alters intracellular metabolism and contributes to the growth of malignant cells. Metabolomics, or the study of small molecules, can reveal insight about cancer progression that other biomarker studies cannot.
Gurparsad Singh Suri, Gurleen Kaur, Giuseppina M. Carbone, Dheeraj Shinde   +3 more
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The future of metabolomics in ELIXIR [PDF]

F1000Research, 2017
Metabolomics, the youngest of the major omics technologies, is supported by an active community of researchers and infrastructure developers across Europe. To coordinate and focus efforts around infrastructure building for metabolomics within Europe, a workshop on the “Future of metabolomics in ELIXIR” was organised at Frankfurt Airport in Germany ...
van Rijswijk, M, van Rijswijk, M, Beirnaert, C, Beirnaert, C, Caron, C, Cascante, M, Dominguez, V, Dunn, WB, Ebbels, TMD, Giacomoni, F, Gonzalez-Beltran, A, Hankemeier, T, Haug, K, Haug, K, Izquierdo-Garcia, JL, Jimenez, RC, Jimenez, RC, Jourdan, F, Kale, N, Klapa, MI, Kohlbacher, O, Koort, K, Kultima, K, Le Corguillé, G, Moreno, P, Moschonas, NK, Moschonas, NK, Neumann, S, O'Donovan, C, Reczko, M, Rocca-Serra, P, Rosato, A, Rosato, A, Rosato, A, Salek, RM, Salek, RM, Sansone, S-A, Satagopam, V, Schober, D, Shimmo, R, Spicer, RA, Spicer, RA, Spjuth, O, Spjuth, O, Spjuth, O, Thévenot, EA, Thévenot, EA, Viant, MR, Weber, RJM, Willighagen, EL, Willighagen, EL, Zanetti, G, Steinbeck, C, Steinbeck, C   +53 more
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Computational Metabolomics: A Framework for the Million Metabolome [PDF]

Chemical Research in Toxicology, 2016
"Sola dosis facit venenum." These words of Paracelsus, "the dose makes the poison", can lead to a cavalier attitude concerning potential toxicities of the vast array of low abundance environmental chemicals to which humans are exposed. Exposome research teaches that 80-85% of human disease is linked to environmental exposures.
Ken Liu, Shuzhao Li, Douglas I. Walker, Douglas I. Walker, Young-Mi Go, Karan Uppal, Dean P. Jones   +6 more
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Extraction for Metabolomics: Access to The Metabolome

Phytochemical Analysis, 2014
ABSTRACTIntroductionThe value of information obtained from a metabolomic study depends on how much of the metabolome is present in analysed samples. Thus, only a comprehensive and reproducible extraction method will provide reliable data because the metabolites that will be measured are those that were extracted and all conclusions will be built around
Mushtaq, M.Y., Choi, Y.H., Verpoorte, R., Wilson, E.G.   +3 more
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Xenobiotic Metabolomics: Major Impact on the Metabolome [PDF]

Annual Review of Pharmacology and Toxicology, 2012
Xenobiotics are encountered by humans on a daily basis and include drugs, environmental pollutants, cosmetics, and even components of the diet. These chemicals undergo metabolism and detoxication to produce numerous metabolites, some of which have the potential to cause unintended effects such as toxicity.
Andrew D. Patterson, Frank J. Gonzalez, Caroline H. Johnson, Jeffrey R. Idle   +3 more
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