Results 1 to 10 of about 151,525 (322)

Capillary Electrophoresis Mass Spectrometry-Based Metabolomics of Plasma Samples from Healthy Subjects in a Cross-Sectional Japanese Population Study

Metabolites, 2021
For large-scale metabolomics, such as in cohort studies, normalization protocols using quality control (QC) samples have been established when using data from gas chromatography and liquid chromatography coupled to mass spectrometry.
Hiroyuki Yamamoto, Makoto Suzuki, Rira Matsuta, Kazunori Sasaki, Moon-Il Kang, Kenjiro Kami, Yota Tatara, Ken Itoh, Shigeyuki Nakaji   +8 more
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Putative imbalanced amino acid metabolism in rainbow trout long term fed a plant-based diet as revealed by 1H-NMR metabolomics

Journal of Nutritional Science, 2021
The long-term effect of a plant (P)-based diet was assessed by proton nuclear magnetic resonance (1H-NMR) metabolomics in rainbow trout fed a marine fish meal (FM)–fish oil (FO) diet (M), a P-based diet and a control commercial-like diet (C) starting ...
Catherine Deborde, Blandine Madji Hounoum, Annick Moing, Mickaël Maucourt, Daniel Jacob, Geneviève Corraze, Françoise Médale, Benoit Fauconneau   +7 more
doaj   +1 more source

Integrative Metabolomics for Assessing the Effect of Insect (Hermetia illucens) Protein Extract on Rainbow Trout Metabolism

Metabolites, 2020
Nutrition of high trophic species in aquaculture is faced with the development of sustainable plant-based diets. Insects seem particularly promising for supplementing plant-based diets.
Simon Roques, Catherine Deborde, Laurence Guimas, Yann Marchand, Nadège Richard, Daniel Jacob, Sandrine Skiba-Cassy, Annick Moing, Benoit Fauconneau   +8 more
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Gut Microbiota as Well as Metabolomes of Wistar Rats Recover within Two Weeks after Doripenem Antibiotic Treatment

Microorganisms, 2023
An understanding of the changes in gut microbiome composition and its associated metabolic functions is important to assess the potential implications thereof on host health.
Aishwarya Murali, Franziska Maria Zickgraf, Philipp Ternes, Varun Giri, Hunter James Cameron, Saskia Sperber, Volker Haake, Peter Driemert, Hennicke Kamp, Dorothee Funk Weyer, Shana J. Sturla, Ivonne M. G. M. Rietjens, Bennard van Ravenzwaay   +12 more
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Antibiotic-Induced Changes in Microbiome-Related Metabolites and Bile Acids in Rat Plasma

Metabolites, 2020
Various environmental factors can alter the gut microbiome’s composition and functionality, and modulate host health. In this study, the effects of oral and parenteral administration of two poorly bioavailable antibiotics (i.e., vancomycin and ...
Véronique de Bruijn, Christina Behr, Saskia Sperber, Tilmann Walk, Philipp Ternes, Markus Slopianka, Volker Haake, Karsten Beekmann, Bennard van Ravenzwaay   +8 more
doaj   +1 more source

Determination of the Minimum Sample Amount for Capillary Electrophoresis-Fourier Transform Mass Spectrometry (CE-FTMS)-Based Metabolomics of Colorectal Cancer Biopsies

Biomedicines, 2023
The minimum sample volume for capillary electrophoresis-Fourier transform mass spectrometry (CE-FTMS) useful for analyzing hydrophilic metabolites was investigated using samples obtained from colorectal cancer patients.
Tetsuo Sugishita, Masanori Tokunaga, Kenjiro Kami, Kozue Terai, Hiroyuki Yamamoto, Hajime Shinohara, Yusuke Kinugasa   +6 more
doaj   +1 more source

Experimental Measurements and Mathematical Modeling of Cytosolic Ca2+ Signatures upon Elicitation by Penta-N-acetylchitopentaose Oligosaccharides in Nicotiana tabacum Cell Cultures

Plants, 2013
Plants have developed sophisticated recognition systems for different kinds of pathogens. Pathogen-associated molecular patterns (PAMPs) can induce various defense mechanisms, e.g., the production of reactive oxygen species (ROS) as an early event. Plant
Kalina Mrozek, Karsten Niehaus, Petra Lutter   +2 more
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Isorhamnetin Has Potential for the Treatment of Escherichia coli-Induced Sepsis

Molecules, 2019
Isorhamnetin is a flavonoid that is abundant in the fruit of Hippophae rhamnoides L. It is widely studied for its ability to modulate inflammatory responses. In this study, we evaluated the potential of isorhamnetin to prevent gram-negative sepsis.
Anil Kumar Chauhan, Jieun Kim, Yeongjoon Lee, Pavithra K. Balasubramanian, Yangmee Kim   +4 more
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Methyl lucidone induces apoptosis and G2/M phase arrest via the PI3K/Akt/NF-κB pathway in ovarian cancer cells

Pharmaceutical Biology, 2020
Context Methyl lucidone (ML) from the dried fruit of Lindera erythrocarpa Makino (Lauraceae) exhibits cytotoxic effects in various cancer cell lines. However, its effects on ovarian cancer cells remain unknown.
Jae-Hwan Yoon, Jong-Woon Shin, Thu-Huyen Pham, Youn-Jin Choi, Hyung-Won Ryu, Sei-Ryang Oh, Jae-Wook Oh, Do-Young Yoon   +7 more
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Development of a polyphagous leaf beetle on different host plant species and its detoxification of glucosinolates

Frontiers in Ecology and Evolution, 2022
Herbivores face a broad range of defences when feeding on plants. By mixing diets, polyphagous herbivores are assumed to benefit during their development by gaining a better nutritional balance and reducing the intake of toxic compounds from individual ...
Jeanne Friedrichs, Rabea Schweiger, Svenja Geisler, Judith M. Neumann, Sullivan J. M. Sadzik, Karsten Niehaus, Caroline Müller   +6 more
doaj   +1 more source