Results 1 to 10 of about 148,249 (221)

Systematic Analysis of Impact of Sampling Regions and Storage Methods on Fecal Gut Microbiome and Metabolome Profiles [PDF]

mSphere, 2020
The contribution of human gastrointestinal (GI) microbiota and metabolites to host health has recently become much clearer. However, many confounding factors can influence the accuracy of gut microbiome and metabolome studies, resulting in ...
Yali Liang, Tianyu Dong, Minjian Chen, Lianping He, Tingzhang Wang, Xingyin Liu, Hang Chang, Jian-Hua Mao, Bo Hang, Antoine M. Snijders, Yankai Xia   +10 more
doaj   +3 more sources

Unraveling anti-inflammatory metabolic signatures of Glycyrrhiza uralensis and isoliquiritigenin through multiomics [PDF]

npj Systems Biology and Applications
Glycyrrhiza uralensis, a key component of over 70% of traditional herbal medicines (Kampo) in Japan, exhibits diverse pharmacological effects, including immunoregulation, anti-tumor, and antioxidant properties.
Saki Kiuchi, Mi Hwa Chung, Hina Sakai, Taiki Nakaya, Katsuya Ohbuchi, Kazuya Tsumagari, Koshi Imami, Yasuhiro Otoguro, Tomoaki Nitta, Hiroyuki Yamamoto, Kazunori Sasaki, Hiroshi Tsugawa   +11 more
doaj   +2 more sources

Capillary Electrophoresis Mass Spectrometry-Based Metabolomics of Plasma Samples from Healthy Subjects in a Cross-Sectional Japanese Population Study

Metabolites, 2021
For large-scale metabolomics, such as in cohort studies, normalization protocols using quality control (QC) samples have been established when using data from gas chromatography and liquid chromatography coupled to mass spectrometry.
Hiroyuki Yamamoto, Makoto Suzuki, Rira Matsuta, Kazunori Sasaki, Moon-Il Kang, Kenjiro Kami, Yota Tatara, Ken Itoh, Shigeyuki Nakaji   +8 more
doaj   +1 more source

Putative imbalanced amino acid metabolism in rainbow trout long term fed a plant-based diet as revealed by 1H-NMR metabolomics

Journal of Nutritional Science, 2021
The long-term effect of a plant (P)-based diet was assessed by proton nuclear magnetic resonance (1H-NMR) metabolomics in rainbow trout fed a marine fish meal (FM)–fish oil (FO) diet (M), a P-based diet and a control commercial-like diet (C) starting ...
Catherine Deborde, Blandine Madji Hounoum, Annick Moing, Mickaël Maucourt, Daniel Jacob, Geneviève Corraze, Françoise Médale, Benoit Fauconneau   +7 more
doaj   +1 more source

Genetic algorithm based two-mode clustering of metabolomics data [PDF]

, 2008
Metabolomics and other omics tools are generally characterized by large data sets with many variables obtained under different environmental conditions.
Berg, R.A., van den, Hageman, J.A., Smilde, A.K., Werf, M.J., van der, Westerhuis, J.A.   +4 more
core   +13 more sources

Integrative Metabolomics for Assessing the Effect of Insect (Hermetia illucens) Protein Extract on Rainbow Trout Metabolism

Metabolites, 2020
Nutrition of high trophic species in aquaculture is faced with the development of sustainable plant-based diets. Insects seem particularly promising for supplementing plant-based diets.
Simon Roques, Catherine Deborde, Laurence Guimas, Yann Marchand, Nadège Richard, Daniel Jacob, Sandrine Skiba-Cassy, Annick Moing, Benoit Fauconneau   +8 more
doaj   +1 more source

Gut Microbiota as Well as Metabolomes of Wistar Rats Recover within Two Weeks after Doripenem Antibiotic Treatment

Microorganisms, 2023
An understanding of the changes in gut microbiome composition and its associated metabolic functions is important to assess the potential implications thereof on host health.
Aishwarya Murali, Franziska Maria Zickgraf, Philipp Ternes, Varun Giri, Hunter James Cameron, Saskia Sperber, Volker Haake, Peter Driemert, Hennicke Kamp, Dorothee Funk Weyer, Shana J. Sturla, Ivonne M. G. M. Rietjens, Bennard van Ravenzwaay   +12 more
doaj   +1 more source

A study of the effects of exercise on the urinary metabolome using normalisation to individual metabolic output [PDF]

, 2015
Aerobic exercise, in spite of its multi-organ benefit and potent effect on the metabolome, has yet to be investigated comprehensively via an untargeted metabolomics technology.
Anthony, Nahoum, Blackburn, Gavin, Daskalaki, Evangelia, Kalna, Gabriela, Watson, David, Zhang, Tong   +5 more
core   +6 more sources

Antibiotic-Induced Changes in Microbiome-Related Metabolites and Bile Acids in Rat Plasma

Metabolites, 2020
Various environmental factors can alter the gut microbiome’s composition and functionality, and modulate host health. In this study, the effects of oral and parenteral administration of two poorly bioavailable antibiotics (i.e., vancomycin and ...
Véronique de Bruijn, Christina Behr, Saskia Sperber, Tilmann Walk, Philipp Ternes, Markus Slopianka, Volker Haake, Karsten Beekmann, Bennard van Ravenzwaay   +8 more
doaj   +1 more source

Determination of the Minimum Sample Amount for Capillary Electrophoresis-Fourier Transform Mass Spectrometry (CE-FTMS)-Based Metabolomics of Colorectal Cancer Biopsies

Biomedicines, 2023
The minimum sample volume for capillary electrophoresis-Fourier transform mass spectrometry (CE-FTMS) useful for analyzing hydrophilic metabolites was investigated using samples obtained from colorectal cancer patients.
Tetsuo Sugishita, Masanori Tokunaga, Kenjiro Kami, Kozue Terai, Hiroyuki Yamamoto, Hajime Shinohara, Yusuke Kinugasa   +6 more
doaj   +1 more source