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OMICS: A Journal of Integrative Biology, 2013 Abstract Metabolomics technologies enable the examination and identification of endogenous biochemical reaction products, revealing information on the precise metabolic pathways and processes within a living cell. Metabolism is either directly or indirectly involved with every aspect of cell function, and metabolomics is thus believed
Aihua, Zhang +4 more
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A study of the effects of exercise on the urinary metabolome using normalisation to individual metabolic output [PDF]
, 2015 Aerobic exercise, in spite of its multi-organ benefit and potent effect on the metabolome, has yet to be investigated comprehensively via an untargeted metabolomics technology.
Anthony, Nahoum +5 more
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Briefings in Bioinformatics, 2017 Elemental metabolomics is quantification and characterization of total concentration of chemical elements in biological samples and monitoring of their changes. Recent advances in inductively coupled plasma mass spectrometry have enabled simultaneous measurement of concentrations of > 70 elements in biological samples.
Zhang, Ping +2 more
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Antibiotic-Induced Changes in Microbiome-Related Metabolites and Bile Acids in Rat Plasma
Metabolites, 2020 Various environmental factors can alter the gut microbiome’s composition and functionality, and modulate host health. In this study, the effects of oral and parenteral administration of two poorly bioavailable antibiotics (i.e., vancomycin and ...
Véronique de Bruijn +8 more
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Biomedicines, 2023 The minimum sample volume for capillary electrophoresis-Fourier transform mass spectrometry (CE-FTMS) useful for analyzing hydrophilic metabolites was investigated using samples obtained from colorectal cancer patients.
Tetsuo Sugishita +6 more
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Current Protocols in Molecular Biology, 2012 AbstractThe metabolome is the terminal downstream product of the genome and consists of the total complement of all the low‐molecular‐weight molecules (metabolites) in a cell, tissue, or organism. Metabolomics aims to measure a wide breadth of small molecules in the context of physiological stimuli or disease states.
Lee D, Roberts +3 more
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Plants, 2013 Plants have developed sophisticated recognition systems for different kinds of pathogens. Pathogen-associated molecular patterns (PAMPs) can induce various defense mechanisms, e.g., the production of reactive oxygen species (ROS) as an early event. Plant
Kalina Mrozek +2 more
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Isorhamnetin Has Potential for the Treatment of Escherichia coli-Induced Sepsis
Molecules, 2019 Isorhamnetin is a flavonoid that is abundant in the fruit of Hippophae rhamnoides L. It is widely studied for its ability to modulate inflammatory responses. In this study, we evaluated the potential of isorhamnetin to prevent gram-negative sepsis.
Anil Kumar Chauhan +4 more
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Pharmaceutical Biology, 2020 Context Methyl lucidone (ML) from the dried fruit of Lindera erythrocarpa Makino (Lauraceae) exhibits cytotoxic effects in various cancer cell lines. However, its effects on ovarian cancer cells remain unknown.
Jae-Hwan Yoon +7 more
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Metabolomics to unveil and understand phenotypic diversity between pathogen populations [PDF]
, 2010 Visceral leishmaniasis is caused by a parasite called Leishmania donovani, which every year infects about half a million people and claims several thousand lives. Existing treatments are now becoming less effective due to the emergence of drug resistance.
A Kamleh +63 more
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