Results 181 to 190 of about 149,513 (318)

Fungal endophyte exo-metabolites alter the morphology and metabolome of the plant pathogen Fusarium graminearum: an LC-MS based metabolomics approach to unravel the biocontrol effect [PDF]

open access: yes, 2020
Ameye, Maarten   +5 more
core  

PIK‐III‐Mediated Elevation of Thiamine Re‐Sensitises Renal Cell Carcinoma to Cuproptosis via Activating PDHA1

open access: yesCell Proliferation, EarlyView.
PIK‐III enhancing the efficacy of cuproptosis to kill renal cancer cells through dysregulating thiamine metabolism and dephosphorylation of pyruvate dehydrogenase complex E1 (PDHA1), providing a potential option for treatment of cuproptosis‐resistant renal cancer by the combination of PIK‐III and elesclomol.
Dongdong Xie   +8 more
wiley   +1 more source

Jia Wei Xiao Yao San ameliorates chronic stress-induced depression-like behaviors in mice by regulating the gut microbiome and brain metabolome in relation to purine metabolism

open access: hybrid, 2022
Shuai Ji   +11 more
openalex   +1 more source

Bacterial porphyrins in healthy skin: Microbiota components impact melanogenesis and age‐related processes leading to Porphyr'ageing

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Porphyrins, previously linked only to acne inflammation, are now implicated in skin ageing. Their presence correlates with increased melanin, inflammation, and oxidative stress, contributing to premature ageing signs. This study introduces the concept of “Porphyr'ageing,” highlighting the detrimental effects of bacterial metabolites on skin health and ...
Marie Meunier   +9 more
wiley   +1 more source

Endocrine and metabolic determinants of cardiometabolic risk in mild autonomous cortisol secretion. [PDF]

open access: yesEBioMedicine
Prete A   +51 more
europepmc   +1 more source

Variation in Microbiome Composition and Faecal Metabolites Are Associated With Differential Susceptibility to DSS‐Induced Colitis

open access: yesImmunology, EarlyView.
C57BL/6 mice from Charles River Laboratories (CR) have enhanced mucosal immune action relative to C57BL/6 mice from Jackson Laboratories (JAX). CR mice are more susceptible to severe DSS‐induced colitis than JAX mice. Co‐housing transfers colitis susceptibility from CR mice to JAX mice.
Jessica M. Till   +8 more
wiley   +1 more source

Development and application of a HILIC UHPLC-MS method for polar fecal metabolome profiling

open access: green, 2019
Nina Sillner   +4 more
openalex   +2 more sources

Elevated Salivary Theobromine and Long‐Term Improvement of Periodontal Health in Two Cohort Studies

open access: yesJournal of Clinical Periodontology, EarlyView.
ABSTRACT Background Theobromine, a methylxanthine mainly found in chocolate, has been suggested to possess various health‐promoting properties. This study aimed to investigate the long‐term effect of salivary theobromine levels on periodontitis severity using 7‐ and 10‐year follow‐up data from the prospective Studies of Health in Pomerania (SHIP‐TREND ...
Thomas Kocher   +8 more
wiley   +1 more source

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