Results 21 to 30 of about 161,779 (333)

HMDB 4.0: the human metabolome database for 2018

Nucleic Acids Res., 2017
The Human Metabolome Database or HMDB (www.hmdb.ca) is a web-enabled metabolomic database containing comprehensive information about human metabolites along with their biological roles, physiological concentrations, disease associations, chemical ...
D. Wishart, Y. D. Feunang, A. Marcu, Anchi Guo, Kevin Y. H. Liang, R. Vázquez-Fresno, Tanvir Sajed, Daniel Johnson, Carin Li, N. Karu, Zinat Sayeeda, Elvis J. Lo, Nazanin Assempour, M. Berjanskii, Sandeep Singhal, David Arndt, Yongjie Liang, Hasan Badran, J. Grant, Arnau Serra-Cayuela, Yifeng Liu, R. Mandal, V. Neveu, Allison Pon, Craig Knox, Michael Wilson, C. Manach, A. Scalbert   +27 more
semanticscholar   +1 more source

Experimental Measurements and Mathematical Modeling of Cytosolic Ca2+ Signatures upon Elicitation by Penta-N-acetylchitopentaose Oligosaccharides in Nicotiana tabacum Cell Cultures

Plants, 2013
Plants have developed sophisticated recognition systems for different kinds of pathogens. Pathogen-associated molecular patterns (PAMPs) can induce various defense mechanisms, e.g., the production of reactive oxygen species (ROS) as an early event. Plant
Kalina Mrozek, Karsten Niehaus, Petra Lutter   +2 more
doaj   +1 more source

Methyl lucidone induces apoptosis and G2/M phase arrest via the PI3K/Akt/NF-κB pathway in ovarian cancer cells

Pharmaceutical Biology, 2020
Context Methyl lucidone (ML) from the dried fruit of Lindera erythrocarpa Makino (Lauraceae) exhibits cytotoxic effects in various cancer cell lines. However, its effects on ovarian cancer cells remain unknown.
Jae-Hwan Yoon, Jong-Woon Shin, Thu-Huyen Pham, Youn-Jin Choi, Hyung-Won Ryu, Sei-Ryang Oh, Jae-Wook Oh, Do-Young Yoon   +7 more
doaj   +1 more source

Mediterranean diet intervention in overweight and obese subjects lowers plasma cholesterol and causes changes in the gut microbiome and metabolome independently of energy intake

Gut, 2020
Objectives This study aimed to explore the effects of an isocaloric Mediterranean diet (MD) intervention on metabolic health, gut microbiome and systemic metabolome in subjects with lifestyle risk factors for metabolic disease.
V. Meslier, M. Laiola, H. Roager, F. De Filippis, H. Roume, B. Quinquis, R. Giacco, I. Mennella, R. Ferracane, N. Pons, Edoardo Pasolli, A. Rivellese, L. Dragsted, P. Vitaglione, S. Ehrlich, D. Ercolini   +15 more
semanticscholar   +1 more source

Identifying metabolites by integrating metabolome databases with mass spectrometry cheminformatics. [PDF]

, 2018
Novel metabolites distinct from canonical pathways can be identified through the integration of three cheminformatics tools: BinVestigate, which queries the BinBase gas chromatography-mass spectrometry (GC-MS) metabolome database to match unknowns with ...
A El-Tayeb, AD Hanson, AL Hartman, Atsushi Ogiwara, C Fattuoni, C Ruttkies, CL Linster, DY Lee, F Allen, Gert Wohlgemuth, GJ Patti, H Sperber, H Tsugawa, H Tsugawa, H Tsugawa, HD Flosadóttir, Hiroshi Tsugawa, I Yamamoto, J Budczies, JG Jeffryes, John Meissen, K Haug, Kohei Takeuchi, M Sud, Masanori Arita, Matthew Mueller, Megan Showalter, MP Styczynski, MR Showalter, O Fiehn, O Fiehn, O Fiehn, O Khersonsky, Oliver Fiehn, Peter Beal, RR da Silva, S Kim, S Kumari, Sajjan Mehta, SE Stein, SM Rappaport, T Kind, Tobias Kind, WR Wikoff, Yuxuan Zheng, Zijuan Lai   +45 more
core   +1 more source

Early antenatal prediction of gestational diabetes in obese women: development of prediction tools for targeted intervention [PDF]

, 2016
All obese women are categorised as being of equally high risk of gestational diabetes (GDM) whereas the majority do not develop the disorder. Lifestyle and pharmacological interventions in unselected obese pregnant women have been unsuccessful in ...
,, Briley, Annette L, Costa Vieira, Matias, Godfrey, Keith M, Lawlor, Debbie A, Nelson, Scott M, Oteng-Ntim, Eugene, Pasupathy, Dharmintra, Poston, Lucilla, Robson, Stephen C, Sattar, Naveed, Seed, Paul T, Welsh, Paul, White, Sara L, Whitworth, Melissa   +14 more
core   +8 more sources

iDMET: network-based approach for integrating differential analysis of cancer metabolomics

BMC Bioinformatics, 2022
Background Comprehensive metabolomic analyses have been conducted in various institutes and a large amount of metabolomic data are now publicly available. To help fully exploit such data and facilitate their interpretation, metabolomic data obtained from
Rira Matsuta, Hiroyuki Yamamoto, Masaru Tomita, Rintaro Saito   +3 more
doaj   +1 more source

Development of a polyphagous leaf beetle on different host plant species and its detoxification of glucosinolates

Frontiers in Ecology and Evolution, 2022
Herbivores face a broad range of defences when feeding on plants. By mixing diets, polyphagous herbivores are assumed to benefit during their development by gaining a better nutritional balance and reducing the intake of toxic compounds from individual ...
Jeanne Friedrichs, Rabea Schweiger, Svenja Geisler, Judith M. Neumann, Sullivan J. M. Sadzik, Karsten Niehaus, Caroline Müller   +6 more
doaj   +1 more source

Sex differences in the human metabolome

Biology of Sex Differences, 2022
Background The sexual dimorphism represents one of the triggers of the metabolic disparities between the organisms, advising about wild implications in research or diagnostics contexts.
M. Costanzo, M. Caterino, G. Sotgiu, M. Ruoppolo, F. Franconi, I. Campesi   +5 more
semanticscholar   +1 more source

mzMatch-ISO: an R tool for the annotation and relative quantification of isotope-labelled mass spectrometry data [PDF]

, 2013
<p>Motivation: Stable isotope-labelling experiments have recently gained increasing popularity in metabolomics studies, providing unique insights into the dynamics of metabolic fluxes, beyond the steady-state information gathered by routine mass ...
Achuthanunni Chokkathukalam, Andris Jankevics, Breitling, Bueschl, Chaneton, Creek, Darren J. Creek, Dunn, Fiona Achcar, Gipson, Jankevics, Kanehisa, Le, Melamud, Michael P. Barrett, Rainer Breitling, Rogers, Scheltema, Smith, t’Kindt, Weber, Wishart   +21 more
core   +6 more sources