White wines’ oxidative stability is related to a flow of chemical reactions involving a number of native wine compounds comprising their antioxidant metabolome. By applying the combination of powerful and modern analytical approaches (EPR, DPPH, and UPLC-
Rémy Romanet +2 more
doaj +1 more source
Simulated microgravity promotes the formation of tridimensional cultures and stimulates pluripotency and a glycolytic metabolism in human hepatic and biliary tree stem/progenitor cells [PDF]
Many pivotal biological cell processes are affected by gravity. The aim of our study was to evaluate biological and functional effects, differentiation potential and exo-metabolome profile of simulated microgravity (SMG) on human hepatic cell line (HepG2)
Alvaro, Domenico +14 more
core +2 more sources
Cancer Metabolomics and the Human Metabolome Database [PDF]
The application of metabolomics towards cancer research has led to a renewed appreciation of metabolism in cancer development and progression. It has also led to the discovery of metabolite cancer biomarkers and the identification of a number of novel cancer causing metabolites.
David S. Wishart +3 more
openaire +3 more sources
mzMatch-ISO: an R tool for the annotation and relative quantification of isotope-labelled mass spectrometry data [PDF]
<p>Motivation: Stable isotope-labelling experiments have recently gained increasing popularity in metabolomics studies, providing unique insights into the dynamics of metabolic fluxes, beyond the steady-state information gathered by routine mass ...
Achuthanunni Chokkathukalam +21 more
core +6 more sources
Identifying metabolites by integrating metabolome databases with mass spectrometry cheminformatics. [PDF]
Novel metabolites distinct from canonical pathways can be identified through the integration of three cheminformatics tools: BinVestigate, which queries the BinBase gas chromatography-mass spectrometry (GC-MS) metabolome database to match unknowns with ...
A El-Tayeb +45 more
core +1 more source
Microbial metabolomics constitutes an integrated component of systems biology. By studying the complete set of metabolites within a microorganism and monitoring the global outcome of interactions between its development processes and the environment, metabolomics can potentially provide a more accurate snap shot of the actual physiological state of the
openaire +2 more sources
Discovery of food identity markers by metabolomics and machine learning technology
Verification of food authenticity establishes consumer trust in food ingredients and components of processed food. Next to genetic or protein markers, chemicals are unique identifiers of food components.
Alexander Erban +7 more
doaj +1 more source
Monophasic Variant of Salmonella Typhimurium Infection Affects the Serum Metabolome in Swine
Salmonella is the most relevant foodborne zoonotic agent found in swine, and its presence in French herds is significant. Its carriage is asymptomatic, which makes it difficult to detect during rearing, thus increasing the risk of its presence on pork ...
Guillaume Larivière-Gauthier +5 more
doaj +1 more source
Heat treatment of bovine colostrum: effects on colostrum metabolome and serum metabolome of calves
Bovine colostrum is important for neonates' health due to its nutritive and non-nutritive components. Heat treatment of colostrum is a well-established management tool, but it may influence colostrum components and affect the health status of calves.
W. Xu, S. Mann, G. Curone, Á. Kenéz
doaj +1 more source
Changes in the milk metabolome of the Giant Panda (Ailuropoda melanoleuca) with time after birth: three phases in early lactation and progressive individual differences [PDF]
Ursids (bears) in general, and giant pandas in particular, are highly altricial at birth. The components of bear milks and their changes with time may be uniquely adapted to nourish relatively immature neonates, protect them from pathogens, and support ...
Hou, Rong +8 more
core +3 more sources

