Results 31 to 40 of about 161,779 (333)

Metabolomics with severity of radiographic knee osteoarthritis and early phase synovitis in middle-aged women from the Iwaki Health Promotion Project: a cross-sectional study

Arthritis Research & Therapy, 2022
Background Osteoarthritis (OA) is one of the costliest and most disabling forms of arthritis, and it poses a major public health burden; however, its detailed etiology, pathophysiology, and metabolism remain unclear.
Eiji Sasaki, Hiroyuki Yamamoto, Toru Asari, Rira Matsuta, Seiya Ota, Yuka Kimura, Shizuka Sasaki, Kyota Ishibashi, Yuji Yamamoto, Kenjiro Kami, Masataka Ando, Eiichi Tsuda, Yasuyuki Ishibashi   +12 more
doaj   +1 more source

Plant Nitrate Reductases Regulate Nitric Oxide Production and Nitrogen-Fixing Metabolism During the Medicago truncatula–Sinorhizobium meliloti Symbiosis

Frontiers in Plant Science, 2020
Nitrate reductase (NR) is the first enzyme of the nitrogen reduction pathway in plants, leading to the production of ammonia. However, in the nitrogen-fixing symbiosis between legumes and rhizobia, atmospheric nitrogen (N2) is directly reduced to ammonia
Antoine Berger, Antoine Berger, Alexandre Boscari, Natasha Horta Araújo, Mickaël Maucourt, Mohamed Hanchi, Stéphane Bernillon, Dominique Rolin, Dominique Rolin, Alain Puppo, Renaud Brouquisse   +10 more
doaj   +1 more source

Homologs of Circadian Clock Proteins Impact the Metabolic Switch Between Light and Dark Growth in the Cyanobacterium Synechocystis sp. PCC 6803

Frontiers in Plant Science, 2021
The putative circadian clock system of the facultative heterotrophic cyanobacterial strain Synechocystis sp. PCC 6803 comprises the following three Kai-based systems: a KaiABC-based potential oscillator that is linked to the SasA-RpaA two-component ...
Nina M. Scheurer, Yogeswari Rajarathinam, Stefan Timm, Christin Köbler, Joachim Kopka, Martin Hagemann, Annegret Wilde   +6 more
doaj   +1 more source

White Wine Antioxidant Metabolome: Definition and Dynamic Behavior during Aging on Lees in Oak Barrels

Antioxidants, 2023
White wines’ oxidative stability is related to a flow of chemical reactions involving a number of native wine compounds comprising their antioxidant metabolome. By applying the combination of powerful and modern analytical approaches (EPR, DPPH, and UPLC-
Rémy Romanet, Régis D. Gougeon, Maria Nikolantonaki   +2 more
doaj   +1 more source

MS-DIAL: Data Independent MS/MS Deconvolution for Comprehensive Metabolome Analysis

Nature Methods, 2015
Data-independent acquisition (DIA) in liquid chromatography (LC) coupled to tandem mass spectrometry (MS/MS) provides comprehensive untargeted acquisition of molecular data.
H. Tsugawa, T. Cajka, T. Kind, Yan Ma, Brendan Higgins, K. Ikeda, Mitsuhiro Kanazawa, J. VanderGheynst, O. Fiehn, Masanori Arita   +9 more
semanticscholar   +1 more source

Aberrant gut microbiota alters host metabolome and impacts renal failure in humans and rodents

Gut, 2020
Objective Patients with renal failure suffer from symptoms caused by uraemic toxins, possibly of gut microbial origin, as deduced from studies in animals. The aim of the study is to characterise relationships between the intestinal microbiome composition,
Xifan Wang, Songtao Yang, Shenghui Li, Liang Zhao, Y. Hao, J. Qin, Lian Zhang, Chengying Zhang, W. Bian, L. Zuo, Xiu Gao, B. Zhu, X. Lei, Zhenglong Gu, Wei Cui, Xiping Xu, Zhiming Li, B. Zhu, Yuan Li, Shangwu Chen, Huiyuan Guo, Hao Zhang, Jing Sun, Ming Zhang, Yan Hui, Xiaoling Zhang, Xiaoxue Liu, bowen sun, Longjiao Wang, Qinglu Qiu, Yu-Chen Zhang, Xingqi Li, Weiqi Liu, Rui Xue, Hong Wu, Donghua Shao, Junling Li, Yuanjie Zhou, Shaochuan Li, Rentao Yang, O. Pedersen, Zhengquan Yu, S. Ehrlich, F. Ren   +43 more
semanticscholar   +1 more source

MiMeDB: the Human Microbial Metabolome Database

Nucleic Acids Res., 2022
The Human Microbial Metabolome Database (MiMeDB) (https://mimedb.org) is a comprehensive, multi-omic, microbiome resource that connects: (i) microbes to microbial genomes; (ii) microbial genomes to microbial metabolites; (iii) microbial metabolites to ...
D. Wishart, Eponine Oler, Harrison Peters, Anchi Guo, Sagan Girod, Scott Han, Sukanta Saha, Vicki W. Lui, Marcia A. LeVatte, Vasuk Gautam, R. Kaddurah-Daouk, N. Karu   +11 more
semanticscholar   +1 more source

Associations among Wine Grape Microbiome, Metabolome, and Fermentation Behavior Suggest Microbial Contribution to Regional Wine Characteristics. [PDF]

, 2016
UnlabelledRegionally distinct wine characteristics (terroir) are an important aspect of wine production and consumer appreciation. Microbial activity is an integral part of wine production, and grape and wine microbiota present regionally defined ...
Allen, Greg, Bokulich, Nicholas A, Collins, Thomas S, Ebeler, Susan E, Heymann, Hildegarde, Masarweh, Chad, Mills, David A   +6 more
core   +2 more sources

HMDB 3.0—The Human Metabolome Database in 2013

Nucleic Acids Res., 2012
The Human Metabolome Database (HMDB) (www.hmdb.ca) is a resource dedicated to providing scientists with the most current and comprehensive coverage of the human metabolome.
D. Wishart, Timothy Jewison, Anchi Guo, Michael Wilson, Craig Knox, Yifeng Liu, Yannick Djoumbou, R. Mandal, Farid Aziat, Edison Dong, Souhaila Bouatra, I. Sinelnikov, David Arndt, J. Xia, Philip Liu, Faizath Yallou, T. Bjorndahl, R. Perez-Pineiro, Roman Eisner, Felicity Allen, V. Neveu, R. Greiner, A. Scalbert   +22 more
semanticscholar   +1 more source

Metabolomic systems biology of trypanosomes [PDF]

, 2010
Metabolomics analysis, which aims at the systematic identification and quantification of all metabolites in biological systems, is emerging as a powerful new tool to identify biomarkers of disease, report on cellular responses to environmental ...
BARBARA M. BAKKER, Cubbon, MICHAEL P. BARRETT, RAINER BREITLING, Shim   +4 more
core   +9 more sources